MUC17

The protein encoded by this gene is a membrane-bound mucin that provides protection to gut epithelial cells. The encoded protein contains about 60 tandem repeats, with each repeat being around 60 aa. N-glycosylation enables the encoded protein to localize on the cell surface, while the C-terminus interacts with the scaffold protein PDZ domain containing 1 (PDZK1). Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015]

Description

Mucin 17, cell surface associated

Tissue specificity

Tissue enriched (intestine)

Predicted location

Membrane

Protein family

Cancer-related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted membrane proteins
Protein evidence (Kim et al 2014)

Chromosome

7 (101020072 - 101058859)

Ensembl ID

ENSG00000169876  (ver. 103.38)

Orthologs

Mouse Muc3: ENSMUSG00000037390

UniProt

Q685J3

neXtProt

NX_Q685J3

Human splice variants
Mouse splice variants

Protein structure