Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11029-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11029-1-AP, RRID:AB_2172040
- Product name
- PSMB4 antibody
- Antibody type
- Polyclonal
- Description
- PSMB4 antibody (Cat. #11029-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Hepatocyte-specific Wtap deficiency promotes hepatocellular carcinoma by activating GRB2-ERK depending on downregulation of proteasome-related genes.
Downregulation of hepatic METTL3 contributes to APAP-induced liver injury in mice.
PSMB4 Degrades the Porcine Reproductive and Respiratory Syndrome Virus Nsp1α Protein via the Autolysosome Pathway and Induces the Production of Type I Interferon.
PSMB4 overexpression enhances the cell growth and viability of breast cancer cells leading to a poor prognosis.
Comparative oncogenomics identifies PSMB4 and SHMT2 as potential cancer driver genes.
Li X, Liu C, Zhang Z, Li X, Yao Z, Dong Y, Wang X, Chen Z
The Journal of biological chemistry 2023 Nov;299(11):105301
The Journal of biological chemistry 2023 Nov;299(11):105301
Downregulation of hepatic METTL3 contributes to APAP-induced liver injury in mice.
Liu C, Li X, Gao M, Dong Y, Chen Z
JHEP reports : innovation in hepatology 2023 Aug;5(8):100766
JHEP reports : innovation in hepatology 2023 Aug;5(8):100766
PSMB4 Degrades the Porcine Reproductive and Respiratory Syndrome Virus Nsp1α Protein via the Autolysosome Pathway and Induces the Production of Type I Interferon.
Yi H, Wang Q, Lu L, Ye R, Xie E, Yu Z, Sun Y, Chen Y, Cai M, Qiu Y, Wu Q, Peng J, Wang H, Zhang G
Journal of virology 2023 Apr 27;97(4):e0026423
Journal of virology 2023 Apr 27;97(4):e0026423
PSMB4 overexpression enhances the cell growth and viability of breast cancer cells leading to a poor prognosis.
Wang H, He Z, Xia L, Zhang W, Xu L, Yue X, Ru X, Xu Y
Oncology reports 2018 Oct;40(4):2343-2352
Oncology reports 2018 Oct;40(4):2343-2352
Comparative oncogenomics identifies PSMB4 and SHMT2 as potential cancer driver genes.
Lee GY, Haverty PM, Li L, Kljavin NM, Bourgon R, Lee J, Stern H, Modrusan Z, Seshagiri S, Zhang Z, Davis D, Stokoe D, Settleman J, de Sauvage FJ, Neve RM
Cancer research 2014 Jun 1;74(11):3114-26
Cancer research 2014 Jun 1;74(11):3114-26
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human placenta tissue were subjected to SDS PAGE followed by western blot with 11029-1-AP(PSMB4 antibody) at dilution of 1:300
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using PSMB4 antibody 11029-1-AP at 1:50 dilution and FITC-labeled donkey anti-rabbit IgG(green). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 11029-1-AP(PSMB4 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue