PAB2301

antibody from Abnova Corporation

Targeting: PAK4

Western blot (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PAB2301

Provider

Abnova Corporation

Proper citation

Abnova Corporation Cat#PAB2301, RRID:AB_1578387

Product name

PAK4 polyclonal antibody

Antibody type

Polyclonal

Description

Rabbit polyclonal antibody raised against synthetic peptide of PAK4.

Storage

Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.

References

Submitted references

p21-activated protein kinase 4 (PAK4) interacts with the keratinocyte growth factor receptor and participates in keratinocyte growth factor-mediated inhibition of oxidant-induced cell death.

Lu Y, Pan ZZ, Devaux Y, Ray P
The Journal of biological chemistry 2003 Mar 21;278(12):10374-80

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Pak to the future.

Bagrodia S, Cerione RA
Trends in cell biology 1999 Sep;9(9):350-5

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PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia.

Abo A, Qu J, Cammarano MS, Dan C, Fritsch A, Baud V, Belisle B, Minden A
The EMBO journal 1998 Nov 16;17(22):6527-40

Western blot

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

The PAK4 polyclonal antibody (Cat # PAB2301) is used in Western blot to detect PAK4 in mouse small intestine tissue lysate.

Immunohistochemistry

Supportive validation

Submitted by

Abnova Corporation (provider)

Main image

Experimental details

Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with the PAK4 polyclonal antibody (Cat # PAB2301) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.

Validation comment

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)