Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- NBP2-29403 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP2-29403, RRID:AB_2800458
- Product name
- Mouse Monoclonal S100A1 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A purified. S100 belongs to the family of calcium binding proteins. S100A and S100B proteins are two members of the S100 family. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. S-100 protein has been found in normal melanocytes, Langerhans cells, histiocytes, chondrocytes, lipocytes, skeletal and cardiac muscle, Schwann cells, epithelial and myoepithelial cells of the breast, salivary and sweat glands, as well as in glial cells. Neoplasms derived from these cells also express S-100 protein, albeit non-uniformly. A large number of well-differentiated tumors of the salivary gland, adipose and cartilaginous tissue, and Schwann cell-derived tumors express S-100 protein. Almost all malignant melanomas and cases of histiocytosis X are positive for S-100 protein. Despite the fact that S-100 protein is an ubiquitous substance, its demonstration is of great value in the identification of several neoplasms, particularly melanomas and their metastases.
- Reactivity
- Human, Mouse, Rat, Bovine
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C.
Submitted references Ex Vivo Assay of Electrical Stimulation to Rat Sciatic Nerves: Cell Behaviors and Growth Factor Expression.
Adipocyte-derived and dedifferentiated fat cells promoting facial nerve regeneration in a rat model.
Recurrent solitary fibrous tumour in the cerebellopontine angle.
Du Z, Bondarenko O, Wang D, Rouabhia M, Zhang Z
Journal of cellular physiology 2016 Jun;231(6):1301-12
Journal of cellular physiology 2016 Jun;231(6):1301-12
Adipocyte-derived and dedifferentiated fat cells promoting facial nerve regeneration in a rat model.
Matsumine H, Takeuchi Y, Sasaki R, Kazama T, Kano K, Matsumoto T, Sakurai H, Miyata M, Yamato M
Plastic and reconstructive surgery 2014 Oct;134(4):686-97
Plastic and reconstructive surgery 2014 Oct;134(4):686-97
Recurrent solitary fibrous tumour in the cerebellopontine angle.
Bikmaz K, Cosar M, Kurtkaya-Yapicier O, Iplikcioglu AC, Gokduman CA
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2005 Sep;12(7):829-32
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2005 Sep;12(7):829-32
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: S100A1 Antibody (4C4.9) [NBP2-29403] - Analysis of human brain lysate using S100 antibody at 1 ug/ml.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: S100A1 Antibody (4C4.9) [NBP2-29403] - Formalin-fixed, paraffin-embedded human melanoma stained with S100 4C4.9 antibody at 1:200 using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: S100A1 Antibody (4C4.9) [NBP2-29403] - Formalin-fixed, paraffin-embedded human melanoma stained with S100 Ab (4C4.9).