BS4663

antibody from Bioworld Technology, Inc
Targeting: CASR FHH, GPRC2A, HHC, HHC1, NSHPT
Provider product page for BS4663

Antibody data

Product number
BS4663 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CaSR (phospho T888) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic phosphopeptide derived from human CaSR around the phosphorylation site of Threonine 888.
Description
The calcium sensing receptor (CaSR) has been shown to play a major role in regulating parathyroid hormone secretion and subsequently influencing the calcium concentration of extracellular fluids. Based on sequence analysis of cDNA clones it appears that the CaSR is similar to the 7-transmembranedomain G-protein-coupled receptor superfamily. Changes in extracellular calcium are thought to modulate a balance between proliferation and differentiation in a variety of cell types. In normal primary keratinocytes and breast epithelial cells, proliferation is inhibited and elevated extracellular calcium levels trigger differentiation. Malignant transformations of these cell types are accompanied by a loss of responsiveness to the anti-proliferative effects of elevated extracellular calcium.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CASR protein structure - BS4663 shown in red.