19125-1-AP

antibody from Proteintech Group

Targeting: CASR FHH, GPRC2A, HHC, HHC1, NSHPT

Provider product page for 19125-1-AP

Western blot

ELISA

Immunocytochemistry

Antibody data

Antibody Data
Antigen structure
References [18]
Comments [0]
Validations
Western blot [1]
Immunocytochemistry [1]

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Product number: 19125-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#19125-1-AP, RRID:AB_10646434
Product name: Calcium Sensing Receptor antibody
Antibody type: Polyclonal
Description: KD/KO validated Calcium Sensing Receptor antibody (Cat. #19125-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB, ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

CASR protein structure - 19125-1-AP shown in red.

Submitted references Calcium-sensing Receptor, a Potential Biomarker Revealed by Large-scale Public Databases and Experimental Verification in Metastatic Breast Cancer.

Xie W, Xu H, Cheng Y, Lin X, Zeng J, Sun Y
Technology in cancer research & treatment 2024 Jan-Dec;23:15330338241254219

High-dose remifentanil exacerbates myocardial ischemia-reperfusion injury through activation of calcium-sensing receptor-mediated pyroptosis.

Zhu Y, Chi J, Cai S, Liu S, Yuan J, Xu H, Zhou H
International journal of medical sciences 2023;20(12):1570-1583

miR-135 protects against atrial fibrillation by suppressing intracellular calcium-mediated NLRP3 inflammasome activation.

Yu Y, Fan Z, Han Y, Sun X, Dong C, Liu G, Yin X, Liu L, Bai Y, Yang B
Journal of cell communication and signaling 2023 Sep;17(3):813-825

Investigation into Antiepileptic Effect of Ganoderic Acid A and Its Mechanism in Seizure Rats Induced by Pentylenetetrazole.

Pang W, Lu S, Zheng R, Li X, Yang S, Feng Y, Wang S, Guo J, Zhou S
BioMed research international 2022;2022:5940372

Calcium-sensing receptor and CPAP-induced neonatal airway hyperreactivity in mice.

Mayer CA, Roos B, Teske J, Wells N, Martin RJ, Chang W, Pabelick CM, Prakash YS, MacFarlane PM
Pediatric research 2022 May;91(6):1391-1398

Calcium released by osteoclastic resorption stimulates autocrine/paracrine activities in local osteogenic cells to promote coupled bone formation.

Ahmed ASI, Sheng MHC, Lau KW, Wilson SM, Wongworawat MD, Tang X, Ghahramanpouri M, Nehme A, Xu Y, Abdipour A, Zhang XB, Wasnik S, Baylink DJ
American journal of physiology. Cell physiology 2022 May 1;322(5):C977-C990

Panaxytriol upregulates CYP3A4 expression based on the interaction of PXR, CAR, HSP90α, and RXRα.

Zhang L, Yan J, Liu J, Meng C, Liu F, Xia C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul;101:154097

The expression of nutrient chemosensing gate molecules in the ileum and colon is altered for goats fed on a high-grain diet.

Tian C, Wu J, Jiao J, Zhou C, Tan Z
Animal science journal = Nihon chikusan Gakkaiho 2022 Jan-Dec;93(1):e13754

Constitutive Androstane Receptor-Mediated Inhibition of Metformin on Phase II Metabolic Enzyme SULT2A1.

Hu X, Li M, Zhang C, Pang S
International journal of endocrinology 2021;2021:8867218

Effects of Sodium Ferulate on Cardiac Hypertrophy Are via the CaSR-Mediated Signaling Pathway.

Chen P, Wen Z, Shi W, Li Z, Chen X, Gao Y, Xu S, Gong Q, Deng J
Frontiers in pharmacology 2021;12:674570

Fructus Ligustri Lucidi aqueous extract promotes calcium balance and short-chain fatty acids production in ovariectomized rats.

Chen B, Wei J, Zhu R, Zhang H, Xia B, Liu Y, Dai X, Ye Z, Tian Y, Li R, Zhao D, Mo F, Orekhov AN, Gao S, Brὃmme D, Wang L, Zhang D
Journal of ethnopharmacology 2021 Oct 28;279:114348

Ginsenoside Rg1 attenuates mechanical stress-induced cardiac injury via calcium sensing receptor-related pathway.

Lu ML, Wang J, Sun Y, Li C, Sun TR, Hou XW, Wang HX
Journal of ginseng research 2021 Nov;45(6):683-694

Renal tubular injury induced by glyphosate combined with hard water: the role of cytosolic phospholipase A2.

Wang R, Chen J, Ding F, Zhang L, Wu X, Wan Y, Hu J, Zhang X, Wu Q
Annals of translational medicine 2021 Jan;9(2):130

Astragaloside IV attenuates myocardial ischemia/reperfusion injury in rats via inhibition of calcium-sensing receptor-mediated apoptotic signaling pathways.

Yin B, Hou XW, Lu ML
Acta pharmacologica Sinica 2019 May;40(5):599-607

miR-429 and miR-424-5p inhibit cell proliferation and Ca(2+) influx by downregulating CaSR in pulmonary artery smooth muscle cells.

Li C, Qin F, Xue M, Lei Y, Hu F, Xu H, Sun G, Wang T, Guo M
American journal of physiology. Cell physiology 2019 Jan 1;316(1):C111-C120

Calhex(231) Alleviates High Glucose-Induced Myocardial Fibrosis via Inhibiting Itch-Ubiquitin Proteasome Pathway in Vitro.

Yuan H, Xu J, Xu X, Gao T, Wang Y, Fan Y, Hu J, Shao Y, Zhao B, Li H, Sun J, Xu C
Biological & pharmaceutical bulletin 2019 Aug 1;42(8):1337-1344

Calcium Sensing Receptor-Related Pathway Contributes to Cardiac Injury and the Mechanism of Astragaloside IV on Cardioprotection.

Lu M, Leng B, He X, Zhang Z, Wang H, Tang F
Frontiers in pharmacology 2018;9:1163

Role of autophagy in cadmium-induced testicular injury.

Wang YJ, Yan J, Yin F, Li L, Qin YG, Meng CY, Lu RF, Guo L
Human & experimental toxicology 2017 Oct;36(10):1039-1048

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: HL-60 cells were subjected to SDS PAGE followed by western blot with 19125-1-AP(CASR antibody) at dilution of 1:400
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunofluorescent analysis of Hela cells, using CASR antibody 19125-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
Sample type: cell line