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Learn10298-1-AP
antibody from Proteintech Group
Targeting: LMNA
CMD1A, HGPS, LGMD1B, LMN1, LMNL1, MADA, PRO1
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ELISAAntibody data
- Antibody Data
- Antigen structure
- References [102]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
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- Product number
- 10298-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10298-1-AP, RRID:AB_2296961
- Product name
- Lamin A/C antibody
- Antibody type
- Polyclonal
- Description
- Lamin A/C antibody (Cat. #10298-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 150ul
Submitted references The Pharmacological Effect and Mechanism of Lanthanum Hydroxide on Vascular Calcification Caused by Chronic Renal Failure Hyperphosphatemia.
Hepatitis B Surface Antigen Suppresses the Activation of Nuclear Factor Kappa B Pathway via Interaction With the TAK1-TAB2 Complex.
Autophagy-Induced HDAC6 Activity During Hypoxia Regulates Mitochondrial Energy Metabolism Through the β-Catenin/COUP-TFII Axis in Hepatocellular Carcinoma Cells.
miR-1258 Attenuates Tumorigenesis Through Targeting E2F1 to Inhibit PCNA and MMP2 Transcription in Glioblastoma.
Adipocyte-Specific Deletion of Lamin A/C Largely Models Human Familial Partial Lipodystrophy Type 2.
Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicing.
Long non-coding RNA NR2F1-AS1 induces breast cancer lung metastatic dormancy by regulating NR2F1 and ΔNp63.
The Retinoblastoma Tumor Suppressor Is Required for the NUP98-HOXA9-Induced Aberrant Nuclear Envelope Phenotype.
Bortezomib potentiates antitumor activity of mitoxantrone through dampening Wnt/β-catenin signal pathway in prostate cancer cells.
Arsenic trioxide induces expression of BCL-2 expression via NF-κB and p38 MAPK signaling pathways in BEAS-2B cells during apoptosis.
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
The miR-378c-Samd1 circuit promotes phenotypic modulation of vascular smooth muscle cells and foam cells formation in atherosclerosis lesions.
The role of LR-TIMAP/PP1c complex in the occurrence and development of no-reflow.
EEF1A2 interacts with HSP90AB1 to promote lung adenocarcinoma metastasis via enhancing TGF-β/SMAD signalling.
Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway.
Virus-inducible IGFALS facilitates innate immune responses by mediating IRAK1 and TRAF6 activation.
Formin-like protein 2 promotes cell proliferation by a p27-related mechanism in human breast cancer cells.
Novel Mutation and Deletion in SUN5 Cause Male Infertility with Acephalic Spermatozoa Syndrome.
Inducible ATP1B1 Upregulates Antiviral Innate Immune Responses by the Ubiquitination of TRAF3 and TRAF6.
Cryptotanshinone, a novel PDK 4 inhibitor, suppresses bladder cancer cell invasiveness via the mTOR/β‑catenin/N‑cadherin axis.
Role of IL-6-IL-27 Complex in Host Antiviral Immune Response.
Nuclear Factor-κB Signaling Mediates Antimony-induced Astrocyte Activation.
Hsa_circ_0005273 facilitates breast cancer tumorigenesis by regulating YAP1-hippo signaling pathway.
Syndecan 4 contributes to osteoclast differentiation induced by RANKL through enhancing autophagy.
Carnosic acid protects against ferroptosis in PC12 cells exposed to erastin through activation of Nrf2 pathway.
Prenylated xanthones from mangosteen (Garcinia mangostana) activate the AhR and Nrf2 pathways and protect intestinal barrier integrity in HT-29 cells.
The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice.
hsa_circ_0068631 promotes breast cancer progression through c-Myc by binding to EIF4A3.
A novel homozygous missense mutation in AK7 causes multiple morphological anomalies of the flagella and oligoasthenoteratozoospermia.
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.
Epiregulin (EREG) and Myocardin Related Transcription Factor A (MRTF-A) Form a Feedforward Loop to Drive Hepatic Stellate Cell Activation.
Heme Oxygenase-1 Suppresses Wnt Signaling Pathway in Nonalcoholic Steatohepatitis-Related Liver Fibrosis.
Single-cell RNA-sequencing analysis identifies host long noncoding RNA MAMDC2-AS1 as a co-factor for HSV-1 nuclear transport.
Hepatitis B Core Antigen Impairs the Polarization While Promoting the Production of Inflammatory Cytokines of M2 Macrophages via the TLR2 Pathway.
Nuclear pore blockade reveals that HIV-1 completes reverse transcription and uncoating in the nucleus.
Inhibition of protein phosphatase methylesterase 1 dysregulates MAP kinase signaling and attenuates muscle cell differentiation.
p62/SQSTM1 accumulation due to degradation inhibition and transcriptional activation plays a critical role in silica nanoparticle-induced airway inflammation via NF-κB activation.
Osteopetrosis-Associated Transmembrane Protein 1 Recruits RNA Exosome To Restrict Hepatitis B Virus Replication.
Overexpression of NRF1-742 or NRF1-772 Reduces Arsenic-Induced Cytotoxicity and Apoptosis in Human HaCaT Keratinocytes.
Cytoplasmic PCNA is located in the actin belt and involved in osteoclast differentiation.
α-Ketoglutarate Modulates Macrophage Polarization Through Regulation of PPARγ Transcription and mTORC1/p70S6K Pathway to Ameliorate ALI/ARDS.
Translation Efficiency and Degradation of ER-Associated mRNAs Modulated by ER-Anchored poly(A)-Specific Ribonuclease (PARN).
Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis.
SSEA3 and Sialyl Lewis a Glycan Expression Is Controlled by B3GALT5 LTR through Lamin A-NFYA and SIRT1-STAT3 Signaling in Human ES Cells.
LL-37 restored glucocorticoid sensitivity impaired by virus dsRNA in lung.
Tissue-Resident Alveolar Macrophages Do Not Rely on Glycolysis for LPS-induced Inflammation.
SOX2 Represses Hepatitis B Virus Replication by Binding to the Viral EnhII/Cp and Inhibiting the Promoter Activation.
N-myc downstream-regulated gene 2 promotes the protein stability of estrogen receptor beta via inhibition of ubiquitin-protein ligase E3A to suppress colorectal cancer.
SARS-CoV-2 Nucleocapsid Protein Interacts with RIG-I and Represses RIG-Mediated IFN-β Production.
Eukaryotic Translation Elongation Factor 1 Delta Inhibits the Nuclear Import of the Nucleoprotein and PA-PB1 Heterodimer of Influenza A Virus.
Torsin ATPases influence chromatin interaction of the Torsin regulator LAP1.
Interplay of m6A and H3K27 trimethylation restrains inflammation during bacterial infection.
Effects of mevalonate kinase interference on cell differentiation, apoptosis, prenylation and geranylgeranylation of human keratinocytes are attenuated by farnesyl pyrophosphate or geranylgeranyl pyrophosphate.
HuR stabilizes HTT mRNA via interacting with its exon 11 in a mutant HTT-dependent manner.
The CDK inhibitor p57Kip2 enhances the activity of the transcriptional coactivator FHL2.
MiR-27a-regulated FOXO1 promotes pancreatic ductal adenocarcinoma cell progression by enhancing Wnt/β-catenin signaling activity.
Inhibition of Influenza A Virus Replication by TRIM14 via Its Multifaceted Protein-Protein Interaction With NP.
miR‑494‑3p regulates lipopolysaccharide‑induced inflammatory responses in RAW264.7 cells by targeting PTEN.
PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma.
Lamin A mutation impairs interaction with nucleoporin NUP155 and disrupts nucleocytoplasmic transport in atrial fibrillation.
Deficiency of heat shock protein A12A promotes browning of white adipose tissues in mice.
YAP mediates the positive regulation of hnRNPK on the lung adenocarcinoma H1299 cell growth.
JNK activation-mediated nuclear SIRT1 protein suppression contributes to silica nanoparticle-induced pulmonary damage via p53 acetylation and cytoplasmic localisation.
HSPA12A Is a Novel Player in Nonalcoholic Steatohepatitis via Promoting Nuclear PKM2-Mediated M1 Macrophage Polarization.
Angiomotin-p130 inhibits β-catenin stability by competing with Axin for binding to tankyrase in breast cancer.
HSF1 phosphorylation by cyclosporin A confers hyperthermia sensitivity through suppression of HSP expression.
Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex.
CRABP2 regulates invasion and metastasis of breast cancer through hippo pathway dependent on ER status.
NAC1 Potentiates Cellular Antiviral Signaling by Bridging MAVS and TBK1.
SKP2 Promotes Hepatocellular Carcinoma Progression Through Nuclear AMPK-SKP2-CARM1 Signaling Transcriptionally Regulating Nutrient-Deprived Autophagy Induction.
Calycosin alleviates allergic contact dermatitis by repairing epithelial tight junctions via down-regulating HIF-1α.
Matrix stiffness mediates stemness characteristics via activating the Yes-associated protein in colorectal cancer cells.
Role of c-Abl-GSK3β Signaling in MPP+-Induced Autophagy-Lysosomal Dysfunction.
Paracrine HGF/c-MET enhances the stem cell-like potential and glycolysis of pancreatic cancer cells via activation of YAP/HIF-1α.
Functional interplay between liver X receptor and AMP-activated protein kinase α inhibits atherosclerosis in apolipoprotein E-deficient mice - a new anti-atherogenic strategy.
SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis.
Activation of hepatic Nogo-B receptor expression-A new anti-liver steatosis mechanism of statins.
Ubiquitination Regulates the Proteasomal Degradation and Nuclear Translocation of the Fat Mass and Obesity-Associated (FTO) Protein.
Baicalein protects human vitiligo melanocytes from oxidative stress through activation of NF-E2-related factor2 (Nrf2) signaling pathway.
Hypoxia-Induced Mitogenic Factor Promotes Cardiac Hypertrophy via Calcium-Dependent and Hypoxia-Inducible Factor-1α Mechanisms.
DExD/H-Box Helicase 36 Signaling via Myeloid Differentiation Primary Response Gene 88 Contributes to NF-κB Activation to Type 2 Porcine Reproductive and Respiratory Syndrome Virus Infection.
PADI2-Mediated Citrullination Promotes Prostate Cancer Progression.
Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20.
ERK1/2-mediated Cytoplasmic Accumulation of hnRNPK Antagonizes TRAIL-induced Apoptosis through Upregulation of XIAP in H1299 Cells.
Highly expressed lncRNA CCND2-AS1 promotes glioma cell proliferation through Wnt/β-catenin signaling.
CRB3 regulates contact inhibition by activating the Hippo pathway in mammary epithelial cells.
TRAIL facilitates cytokine expression and macrophage migration during hypoxia/reoxygenation via ER stress-dependent NF-κB pathway.
TRIM52: A nuclear TRIM protein that positively regulates the nuclear factor-kappa B signaling pathway.
Cluster of Differentiation 36 Deficiency Aggravates Macrophage Infiltration and Hepatic Inflammation by Upregulating Monocyte Chemotactic Protein-1 Expression of Hepatocytes Through Histone Deacetylase 2-Dependent Pathway.
Nuclear retention of the lncRNA SNHG1 by doxorubicin attenuates hnRNPC-p53 protein interactions.
CRB3 downregulation confers breast cancer stem cell traits through TAZ/β-catenin.
Biallelic SUN5 Mutations Cause Autosomal-Recessive Acephalic Spermatozoa Syndrome.
Dicer interacts with SIRT7 and regulates H3K18 deacetylation in response to DNA damaging agents.
Set7 facilitates hepatitis C virus replication via enzymatic activity-dependent attenuation of the IFN-related pathway.
miR-206 modulates lipopolysaccharide-mediated inflammatory cytokine production in human astrocytes.
Novel function of PITH domain-containing 1 as an activator of internal ribosomal entry site to enhance RUNX1 expression and promote megakaryocyte differentiation.
Protective effect of astaxanthin on liver fibrosis through modulation of TGF-β1 expression and autophagy.
FHL2-driven molecular network mediated Septin2 knockdown inducing apoptosis in mesangial cell.
Novel function of the chromosome 7 open reading frame 41 gene to promote leukemic megakaryocyte differentiation by modulating TPA-induced signaling.
UDP-glucose dehydrogenase modulates proteoglycan synthesis in articular chondrocytes: its possible involvement and regulation in osteoarthritis.
Proteomic analysis of primary duck hepatocytes infected with duck hepatitis B virus.
Proteomic analysis of protein complexes in human SH-SY5Y neuroblastoma cells by using blue-native gel electrophoresis: an increase in lamin A/C associated with heat shock protein 90 in response to 6-hydroxydopamine-induced oxidative stress.
Zhao L, Wang S, Liu H, Du X, Bu R, Li B, Han R, Gao J, Liu Y, Hao J, Zhao J, Meng Y, Li G
Frontiers in cell and developmental biology 2021;9:639127
Frontiers in cell and developmental biology 2021;9:639127
Hepatitis B Surface Antigen Suppresses the Activation of Nuclear Factor Kappa B Pathway via Interaction With the TAK1-TAB2 Complex.
Deng F, Xu G, Cheng Z, Huang Y, Ma C, Luo C, Yu C, Wang J, Xu X, Liu S, Zhu Y
Frontiers in immunology 2021;12:618196
Frontiers in immunology 2021;12:618196
Autophagy-Induced HDAC6 Activity During Hypoxia Regulates Mitochondrial Energy Metabolism Through the β-Catenin/COUP-TFII Axis in Hepatocellular Carcinoma Cells.
Yan X, Qu X, Liu B, Zhao Y, Xu L, Yu S, Wang J, Wang L, Su J
Frontiers in oncology 2021;11:742460
Frontiers in oncology 2021;11:742460
miR-1258 Attenuates Tumorigenesis Through Targeting E2F1 to Inhibit PCNA and MMP2 Transcription in Glioblastoma.
Qin H, Gui Y, Ma R, Zhang H, Guo Y, Ye Y, Li J, Zhao L, Wang Y
Frontiers in oncology 2021;11:671144
Frontiers in oncology 2021;11:671144
Adipocyte-Specific Deletion of Lamin A/C Largely Models Human Familial Partial Lipodystrophy Type 2.
Corsa CAS, Walsh CM, Bagchi DP, Foss Freitas MC, Li Z, Hardij J, Granger K, Mori H, Schill RL, Lewis KT, Maung JN, Azaria RD, Rothberg AE, Oral EA, MacDougald OA
Diabetes 2021 Sep;70(9):1970-1984
Diabetes 2021 Sep;70(9):1970-1984
Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicing.
Zhang Q, Zhang J, Ye J, Li X, Liu H, Ma X, Wang C, He K, Zhang W, Yuan J, Zhao Y, Xu H, Liu Q
Molecular neurodegeneration 2021 Sep 22;16(1):66
Molecular neurodegeneration 2021 Sep 22;16(1):66
Long non-coding RNA NR2F1-AS1 induces breast cancer lung metastatic dormancy by regulating NR2F1 and ΔNp63.
Liu Y, Zhang P, Wu Q, Fang H, Wang Y, Xiao Y, Cong M, Wang T, He Y, Ma C, Tian P, Liang Y, Qin LX, Yang Q, Yang Q, Liao L, Hu G
Nature communications 2021 Sep 2;12(1):5232
Nature communications 2021 Sep 2;12(1):5232
The Retinoblastoma Tumor Suppressor Is Required for the NUP98-HOXA9-Induced Aberrant Nuclear Envelope Phenotype.
Vaz M, Fahrenkrog B
Cells 2021 Oct 22;10(11)
Cells 2021 Oct 22;10(11)
Bortezomib potentiates antitumor activity of mitoxantrone through dampening Wnt/β-catenin signal pathway in prostate cancer cells.
Zhang Y, Liu Q, Wei W, Zhang G, Yan S, Dai R, Sun Y, Su D, Lv S, Xia Y, Li J, Li C
BMC cancer 2021 Oct 13;21(1):1101
BMC cancer 2021 Oct 13;21(1):1101
Arsenic trioxide induces expression of BCL-2 expression via NF-κB and p38 MAPK signaling pathways in BEAS-2B cells during apoptosis.
Tang J, Yao C, Liu Y, Yuan J, Wu L, Hosoi K, Yu S, Huang C, Wei H, Chen G
Ecotoxicology and environmental safety 2021 Oct 1;222:112531
Ecotoxicology and environmental safety 2021 Oct 1;222:112531
HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma.
Tian T, Hong F, Wang Z, Hu J, Chen N, Lv L, Yi Q
Cell death discovery 2021 Nov 8;7(1):341
Cell death discovery 2021 Nov 8;7(1):341
The miR-378c-Samd1 circuit promotes phenotypic modulation of vascular smooth muscle cells and foam cells formation in atherosclerosis lesions.
Tian S, Cao Y, Wang J, Bi Y, Zhong J, Meng X, Sun W, Yang R, Gan L, Wang X, Li H, Wang R
Scientific reports 2021 May 18;11(1):10548
Scientific reports 2021 May 18;11(1):10548
The role of LR-TIMAP/PP1c complex in the occurrence and development of no-reflow.
Quan X, Liu X, Qin X, Wang Y, Sun T, Li Z, Zhu L, Chen J, Zhou Y, Singh S, Dong H, Zhang Z, Zhang H
EBioMedicine 2021 Mar;65:103251
EBioMedicine 2021 Mar;65:103251
EEF1A2 interacts with HSP90AB1 to promote lung adenocarcinoma metastasis via enhancing TGF-β/SMAD signalling.
Jia L, Ge X, Du C, Chen L, Zhou Y, Xiong W, Xiang J, Li G, Xiao G, Fang L, Li Z
British journal of cancer 2021 Mar;124(7):1301-1311
British journal of cancer 2021 Mar;124(7):1301-1311
Extracellular vesicles derived from oesophageal cancer containing P4HB promote muscle wasting via regulating PHGDH/Bcl-2/caspase-3 pathway.
Gao X, Wang Y, Lu F, Chen X, Yang D, Cao Y, Zhang W, Chen J, Zheng L, Wang G, Fu M, Ma L, Song Y, Zhan Q
Journal of extracellular vesicles 2021 Mar;10(5):e12060
Journal of extracellular vesicles 2021 Mar;10(5):e12060
Virus-inducible IGFALS facilitates innate immune responses by mediating IRAK1 and TRAF6 activation.
Xu G, Deng F, Zuo Q, Liu L, Dou K, Cheng Z, Cao W, Luo C, Yu C, Liu S, Zhu Y
Cellular & molecular immunology 2021 Jun;18(6):1587-1589
Cellular & molecular immunology 2021 Jun;18(6):1587-1589
Formin-like protein 2 promotes cell proliferation by a p27-related mechanism in human breast cancer cells.
Jiao X, Wang B, Feng C, Song S, Tian B, Zhou C, Gao X, Sun W, Liu P
BMC cancer 2021 Jun 30;21(1):760
BMC cancer 2021 Jun 30;21(1):760
Novel Mutation and Deletion in SUN5 Cause Male Infertility with Acephalic Spermatozoa Syndrome.
Xiang M, Wang Y, Wang K, Kong S, Lu M, Zhang J, Duan Z, Zha X, Shi X, Wang F, Cao Y, Zhu F
Reproductive sciences (Thousand Oaks, Calif.) 2021 Jun 22;
Reproductive sciences (Thousand Oaks, Calif.) 2021 Jun 22;
Inducible ATP1B1 Upregulates Antiviral Innate Immune Responses by the Ubiquitination of TRAF3 and TRAF6.
Cao W, Guo Y, Cheng Z, Xu G, Zuo Q, Nie L, Huang Y, Liu S, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2668-2681
Journal of immunology (Baltimore, Md. : 1950) 2021 Jun 1;206(11):2668-2681
Cryptotanshinone, a novel PDK 4 inhibitor, suppresses bladder cancer cell invasiveness via the mTOR/β‑catenin/N‑cadherin axis.
Kim CJ, Terado T, Tambe Y, Mukaisho KI, Kageyama S, Kawauchi A, Inoue H
International journal of oncology 2021 Jul;59(1)
International journal of oncology 2021 Jul;59(1)
Role of IL-6-IL-27 Complex in Host Antiviral Immune Response.
Zuo Q, Cheng Z, Zhang G, Xia Y, Xu G, Cao W, Yang X, Fu Y, He R, Fang P, Guo Y, Nie L, Huang Y, Liu L, Zhan J, Liu S, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 15;207(2):577-589
Journal of immunology (Baltimore, Md. : 1950) 2021 Jul 15;207(2):577-589
Nuclear Factor-κB Signaling Mediates Antimony-induced Astrocyte Activation.
Zhang T, Zheng YD, Jiao M, Zhi Y, Xu SY, Zhu PY, Zhao XY, Wu QY
Biomedical and environmental sciences : BES 2021 Jan 20;34(1):29-39
Biomedical and environmental sciences : BES 2021 Jan 20;34(1):29-39
Hsa_circ_0005273 facilitates breast cancer tumorigenesis by regulating YAP1-hippo signaling pathway.
Wang X, Ji C, Hu J, Deng X, Zheng W, Yu Y, Hua K, Zhou X, Fang L
Journal of experimental & clinical cancer research : CR 2021 Jan 12;40(1):29
Journal of experimental & clinical cancer research : CR 2021 Jan 12;40(1):29
Syndecan 4 contributes to osteoclast differentiation induced by RANKL through enhancing autophagy.
Li J, Sun Z, Lin Y, Yan Y, Yan H, Jing B, Han Z
International immunopharmacology 2021 Feb;91:107275
International immunopharmacology 2021 Feb;91:107275
Carnosic acid protects against ferroptosis in PC12 cells exposed to erastin through activation of Nrf2 pathway.
Cheng J, Xu T, Xun C, Guo H, Cao R, Gao S, Sheng W
Life sciences 2021 Feb 1;266:118905
Life sciences 2021 Feb 1;266:118905
Prenylated xanthones from mangosteen (Garcinia mangostana) activate the AhR and Nrf2 pathways and protect intestinal barrier integrity in HT-29 cells.
Tocmo R, Le B, Heun A, van Pijkeren JP, Parkin K, Johnson JJ
Free radical biology & medicine 2021 Feb 1;163:102-115
Free radical biology & medicine 2021 Feb 1;163:102-115
The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice.
Xu Q, Fu Q, Li Z, Liu H, Wang Y, Lin X, He R, Zhang X, Ju Z, Campisi J, Kirkland JL, Sun Y
Nature metabolism 2021 Dec;3(12):1706-1726
Nature metabolism 2021 Dec;3(12):1706-1726
hsa_circ_0068631 promotes breast cancer progression through c-Myc by binding to EIF4A3.
Wang X, Chen M, Fang L
Molecular therapy. Nucleic acids 2021 Dec 3;26:122-134
Molecular therapy. Nucleic acids 2021 Dec 3;26:122-134
A novel homozygous missense mutation in AK7 causes multiple morphological anomalies of the flagella and oligoasthenoteratozoospermia.
Xiang M, Wang Y, Xu W, Zheng N, Deng H, Zhang J, Duan Z, Zha X, Zhang W, Song G, Shi X, Wang F, Cao Y, Zhu F
Journal of assisted reproduction and genetics 2021 Dec 2;
Journal of assisted reproduction and genetics 2021 Dec 2;
AKR1B10 negatively regulates autophagy through reducing GAPDH upon glucose starvation in colon cancer.
Li W, Liu C, Huang Z, Shi L, Zhong C, Zhou W, Meng P, Li Z, Wang S, Luo F, Yan J, Wu T
Journal of cell science 2021 Apr 15;134(8)
Journal of cell science 2021 Apr 15;134(8)
Epiregulin (EREG) and Myocardin Related Transcription Factor A (MRTF-A) Form a Feedforward Loop to Drive Hepatic Stellate Cell Activation.
Wu X, Dong W, Zhang T, Ren H, Wang J, Shang L, Zhu Z, Zhu W, Shi X, Xu Y
Frontiers in cell and developmental biology 2020;8:591246
Frontiers in cell and developmental biology 2020;8:591246
Heme Oxygenase-1 Suppresses Wnt Signaling Pathway in Nonalcoholic Steatohepatitis-Related Liver Fibrosis.
Du J, Ren W, Zhang Q, Fu N, Han F, Cui P, Li W, Kong L, Zhao S, Wang R, Zhang Y, Yang L, Kong L, Nan Y
BioMed research international 2020;2020:4910601
BioMed research international 2020;2020:4910601
Single-cell RNA-sequencing analysis identifies host long noncoding RNA MAMDC2-AS1 as a co-factor for HSV-1 nuclear transport.
Wang Y, Huang L, Wang Y, Luo W, Li F, Xiao J, Qin S, Wang Z, Song X, Wang Y, Jin F, Wang Y
International journal of biological sciences 2020;16(9):1586-1603
International journal of biological sciences 2020;16(9):1586-1603
Hepatitis B Core Antigen Impairs the Polarization While Promoting the Production of Inflammatory Cytokines of M2 Macrophages via the TLR2 Pathway.
Yi H, Zhang Y, Yang X, Li M, Hu H, Xiong J, Wang N, Jin J, Zhang Y, Song Y, Wang X, Chen L, Lian J
Frontiers in immunology 2020;11:535
Frontiers in immunology 2020;11:535
Nuclear pore blockade reveals that HIV-1 completes reverse transcription and uncoating in the nucleus.
Dharan A, Bachmann N, Talley S, Zwikelmaier V, Campbell EM
Nature microbiology 2020 Sep;5(9):1088-1095
Nature microbiology 2020 Sep;5(9):1088-1095
Inhibition of protein phosphatase methylesterase 1 dysregulates MAP kinase signaling and attenuates muscle cell differentiation.
Labuzan SA, Lynch SA, Cooper LM, Waddell DS
Gene 2020 May 20;739:144515
Gene 2020 May 20;739:144515
p62/SQSTM1 accumulation due to degradation inhibition and transcriptional activation plays a critical role in silica nanoparticle-induced airway inflammation via NF-κB activation.
Wu Y, Jin Y, Sun T, Zhu P, Li J, Zhang Q, Wang X, Jiang J, Chen G, Zhao X
Journal of nanobiotechnology 2020 May 19;18(1):77
Journal of nanobiotechnology 2020 May 19;18(1):77
Osteopetrosis-Associated Transmembrane Protein 1 Recruits RNA Exosome To Restrict Hepatitis B Virus Replication.
Ma C, Xu W, Yang Q, Liu W, Xiang Q, Chen J, Zhang Q, Liu Y, Wu K, Wu J
Journal of virology 2020 May 18;94(11)
Journal of virology 2020 May 18;94(11)
Overexpression of NRF1-742 or NRF1-772 Reduces Arsenic-Induced Cytotoxicity and Apoptosis in Human HaCaT Keratinocytes.
Wang S, Cheng H, Wang L, Zhao R, Guan D
International journal of molecular sciences 2020 Mar 16;21(6)
International journal of molecular sciences 2020 Mar 16;21(6)
Cytoplasmic PCNA is located in the actin belt and involved in osteoclast differentiation.
Tang D, Liu X, Chen K, Li Z, Dai Y, Xu J, Zhang HT, Gao X, Liu L
Aging 2020 Jun 27;12(13):13297-13317
Aging 2020 Jun 27;12(13):13297-13317
α-Ketoglutarate Modulates Macrophage Polarization Through Regulation of PPARγ Transcription and mTORC1/p70S6K Pathway to Ameliorate ALI/ARDS.
Liu M, Chen Y, Wang S, Zhou H, Feng D, Wei J, Shi X, Wu L, Zhang P, Yang H, Lv X
Shock (Augusta, Ga.) 2020 Jan;53(1):103-113
Shock (Augusta, Ga.) 2020 Jan;53(1):103-113
Translation Efficiency and Degradation of ER-Associated mRNAs Modulated by ER-Anchored poly(A)-Specific Ribonuclease (PARN).
Duan TL, Jiao H, He GJ, Yan YB
Cells 2020 Jan 9;9(1)
Cells 2020 Jan 9;9(1)
Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis.
Feng J, Dai W, Mao Y, Wu L, Li J, Chen K, Yu Q, Kong R, Li S, Zhang J, Ji J, Wu J, Mo W, Xu X, Guo C
Journal of experimental & clinical cancer research : CR 2020 Jan 30;39(1):24
Journal of experimental & clinical cancer research : CR 2020 Jan 30;39(1):24
SSEA3 and Sialyl Lewis a Glycan Expression Is Controlled by B3GALT5 LTR through Lamin A-NFYA and SIRT1-STAT3 Signaling in Human ES Cells.
Cai BH, Lee HY, Chou CK, Wu PH, Huang HC, Chao CC, Chung HY, Kannagi R
Cells 2020 Jan 10;9(1)
Cells 2020 Jan 10;9(1)
LL-37 restored glucocorticoid sensitivity impaired by virus dsRNA in lung.
Li K, Tao N, Zheng L, Sun T
International immunopharmacology 2020 Feb;79:106057
International immunopharmacology 2020 Feb;79:106057
Tissue-Resident Alveolar Macrophages Do Not Rely on Glycolysis for LPS-induced Inflammation.
Woods PS, Kimmig LM, Meliton AY, Sun KA, Tian Y, O'Leary EM, Gökalp GA, Hamanaka RB, Mutlu GM
American journal of respiratory cell and molecular biology 2020 Feb;62(2):243-255
American journal of respiratory cell and molecular biology 2020 Feb;62(2):243-255
SOX2 Represses Hepatitis B Virus Replication by Binding to the Viral EnhII/Cp and Inhibiting the Promoter Activation.
Yang H, Mo J, Xiang Q, Zhao P, Song Y, Yang G, Wu K, Liu Y, Liu W, Wu J
Viruses 2020 Feb 29;12(3)
Viruses 2020 Feb 29;12(3)
N-myc downstream-regulated gene 2 promotes the protein stability of estrogen receptor beta via inhibition of ubiquitin-protein ligase E3A to suppress colorectal cancer.
Zhu J, Lv Y, Hao J, Shi T, Wang S, Wang K, Fan X, Guo Y, Zhang J, Li J
Journal of gastrointestinal oncology 2020 Dec;11(6):1200-1213
Journal of gastrointestinal oncology 2020 Dec;11(6):1200-1213
SARS-CoV-2 Nucleocapsid Protein Interacts with RIG-I and Represses RIG-Mediated IFN-β Production.
Chen K, Xiao F, Hu D, Ge W, Tian M, Wang W, Pan P, Wu K, Wu J
Viruses 2020 Dec 30;13(1)
Viruses 2020 Dec 30;13(1)
Eukaryotic Translation Elongation Factor 1 Delta Inhibits the Nuclear Import of the Nucleoprotein and PA-PB1 Heterodimer of Influenza A Virus.
Gao Q, Yang C, Ren C, Zhang S, Gao X, Jin M, Chen H, Ma W, Zhou H
Journal of virology 2020 Dec 22;95(2)
Journal of virology 2020 Dec 22;95(2)
Torsin ATPases influence chromatin interaction of the Torsin regulator LAP1.
Luithle N, de Bos JU, Hovius R, Maslennikova D, Lewis RT, Ungricht R, Fierz B, Kutay U
eLife 2020 Dec 15;9
eLife 2020 Dec 15;9
Interplay of m6A and H3K27 trimethylation restrains inflammation during bacterial infection.
Wu C, Chen W, He J, Jin S, Liu Y, Yi Y, Gao Z, Yang J, Yang J, Cui J, Zhao W
Science advances 2020 Aug;6(34):eaba0647
Science advances 2020 Aug;6(34):eaba0647
Effects of mevalonate kinase interference on cell differentiation, apoptosis, prenylation and geranylgeranylation of human keratinocytes are attenuated by farnesyl pyrophosphate or geranylgeranyl pyrophosphate.
Li M, Min W, Wang J, Wang L, Li Y, Zhou N, Yang Z, Qian Q
Experimental and therapeutic medicine 2020 Apr;19(4):2861-2870
Experimental and therapeutic medicine 2020 Apr;19(4):2861-2870
HuR stabilizes HTT mRNA via interacting with its exon 11 in a mutant HTT-dependent manner.
Zhao Q, Li C, Yu M, Sun Y, Wang J, Ma L, Sun X, Lu B
RNA biology 2020 Apr;17(4):500-516
RNA biology 2020 Apr;17(4):500-516
The CDK inhibitor p57Kip2 enhances the activity of the transcriptional coactivator FHL2.
Kullmann MK, Podmirseg SR, Roilo M, Hengst L
Scientific reports 2020 Apr 28;10(1):7140
Scientific reports 2020 Apr 28;10(1):7140
MiR-27a-regulated FOXO1 promotes pancreatic ductal adenocarcinoma cell progression by enhancing Wnt/β-catenin signaling activity.
Ling J, Dong X, Wang L, Xue Y, Jia X, Song W, Li Q
American journal of translational research 2019;11(5):3069-3080
American journal of translational research 2019;11(5):3069-3080
Inhibition of Influenza A Virus Replication by TRIM14 via Its Multifaceted Protein-Protein Interaction With NP.
Wu X, Wang J, Wang S, Wu F, Chen Z, Li C, Cheng G, Qin FX
Frontiers in microbiology 2019;10:344
Frontiers in microbiology 2019;10:344
miR‑494‑3p regulates lipopolysaccharide‑induced inflammatory responses in RAW264.7 cells by targeting PTEN.
Zhang S, He K, Zhou W, Cao J, Jin Z
Molecular medicine reports 2019 May;19(5):4288-4296
Molecular medicine reports 2019 May;19(5):4288-4296
PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma.
Feng J, Wu L, Ji J, Chen K, Yu Q, Zhang J, Chen J, Mao Y, Wang F, Dai W, Xu L, Wu J, Guo C
Journal of experimental & clinical cancer research : CR 2019 May 17;38(1):204
Journal of experimental & clinical cancer research : CR 2019 May 17;38(1):204
Lamin A mutation impairs interaction with nucleoporin NUP155 and disrupts nucleocytoplasmic transport in atrial fibrillation.
Han M, Zhao M, Cheng C, Huang Y, Han S, Li W, Tu X, Luo X, Yu X, Liu Y, Chen Q, Ren X, Wang QK, Ke T
Human mutation 2019 Mar;40(3):310-325
Human mutation 2019 Mar;40(3):310-325
Deficiency of heat shock protein A12A promotes browning of white adipose tissues in mice.
Cheng H, Qi T, Zhang X, Kong Q, Min X, Mao Q, Cao X, Liu L, Ding Z
Biochimica et biophysica acta. Molecular basis of disease 2019 Jun 1;1865(6):1451-1459
Biochimica et biophysica acta. Molecular basis of disease 2019 Jun 1;1865(6):1451-1459
YAP mediates the positive regulation of hnRNPK on the lung adenocarcinoma H1299 cell growth.
Xu L, Zhang T, Huang W, Liu X, Lu J, Gao X, Zhang YF, Liu L
Acta biochimica et biophysica Sinica 2019 Jul 10;51(7):677-687
Acta biochimica et biophysica Sinica 2019 Jul 10;51(7):677-687
JNK activation-mediated nuclear SIRT1 protein suppression contributes to silica nanoparticle-induced pulmonary damage via p53 acetylation and cytoplasmic localisation.
Zhao X, Wu Y, Li J, Li D, Jin Y, Zhu P, Liu Y, Zhuang Y, Yu S, Cao W, Wei H, Wang X, Han Y, Chen G
Toxicology 2019 Jul 1;423:42-53
Toxicology 2019 Jul 1;423:42-53
HSPA12A Is a Novel Player in Nonalcoholic Steatohepatitis via Promoting Nuclear PKM2-Mediated M1 Macrophage Polarization.
Kong Q, Li N, Cheng H, Zhang X, Cao X, Qi T, Dai L, Zhang Z, Chen X, Li C, Li Y, Xue B, Fang L, Liu L, Ding Z
Diabetes 2019 Feb;68(2):361-376
Diabetes 2019 Feb;68(2):361-376
Angiomotin-p130 inhibits β-catenin stability by competing with Axin for binding to tankyrase in breast cancer.
Yang J, Zhang X, Chen Z, Shen Y, Wang F, Wang Y, Liu Y, Liu P, Yang J
Cell death & disease 2019 Feb 21;10(3):179
Cell death & disease 2019 Feb 21;10(3):179
HSF1 phosphorylation by cyclosporin A confers hyperthermia sensitivity through suppression of HSP expression.
Shao J, Han B, Cao P, Zhang B, Liu M, Li D, Zhou N, Hao Q, Duan X, Chang Y, Nakai A, Fan Y, Tan K
Biochimica et biophysica acta. Gene regulatory mechanisms 2019 Aug;1862(8):846-857
Biochimica et biophysica acta. Gene regulatory mechanisms 2019 Aug;1862(8):846-857
Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex.
Xu G, Xia Z, Deng F, Liu L, Wang Q, Yu Y, Wang F, Zhu C, Liu W, Cheng Z, Zhu Y, Zhou L, Zhang Y, Lu M, Liu S
PLoS pathogens 2019 Aug;15(8):e1008002
PLoS pathogens 2019 Aug;15(8):e1008002
CRABP2 regulates invasion and metastasis of breast cancer through hippo pathway dependent on ER status.
Feng X, Zhang M, Wang B, Zhou C, Mu Y, Li J, Liu X, Wang Y, Song Z, Liu P
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):361
Journal of experimental & clinical cancer research : CR 2019 Aug 16;38(1):361
NAC1 Potentiates Cellular Antiviral Signaling by Bridging MAVS and TBK1.
Xia Z, Xu G, Nie L, Liu L, Peng N, He Q, Zuo Q, Zhou Y, Cao Z, Liu S, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2019 Aug 15;203(4):1001-1011
Journal of immunology (Baltimore, Md. : 1950) 2019 Aug 15;203(4):1001-1011
SKP2 Promotes Hepatocellular Carcinoma Progression Through Nuclear AMPK-SKP2-CARM1 Signaling Transcriptionally Regulating Nutrient-Deprived Autophagy Induction.
Wei X, Li X, Yan W, Zhang X, Sun Y, Zhang F
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(6):2484-2497
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(6):2484-2497
Calycosin alleviates allergic contact dermatitis by repairing epithelial tight junctions via down-regulating HIF-1α.
Jia Z, Wang X, Wang X, Wei P, Li L, Wu P, Hong M
Journal of cellular and molecular medicine 2018 Sep;22(9):4507-4521
Journal of cellular and molecular medicine 2018 Sep;22(9):4507-4521
Matrix stiffness mediates stemness characteristics via activating the Yes-associated protein in colorectal cancer cells.
Tan F, Huang Y, Pei Q, Liu H, Pei H, Zhu H
Journal of cellular biochemistry 2018 Sep 14;
Journal of cellular biochemistry 2018 Sep 14;
Role of c-Abl-GSK3β Signaling in MPP+-Induced Autophagy-Lysosomal Dysfunction.
Ren Y, Chen J, Wu X, Gui C, Mao K, Zou F, Li W
Toxicological sciences : an official journal of the Society of Toxicology 2018 Sep 1;165(1):232-243
Toxicological sciences : an official journal of the Society of Toxicology 2018 Sep 1;165(1):232-243
Paracrine HGF/c-MET enhances the stem cell-like potential and glycolysis of pancreatic cancer cells via activation of YAP/HIF-1α.
Yan B, Jiang Z, Cheng L, Chen K, Zhou C, Sun L, Qian W, Li J, Cao J, Xu Q, Ma Q, Lei J
Experimental cell research 2018 Oct 1;371(1):63-71
Experimental cell research 2018 Oct 1;371(1):63-71
Functional interplay between liver X receptor and AMP-activated protein kinase α inhibits atherosclerosis in apolipoprotein E-deficient mice - a new anti-atherogenic strategy.
Ma C, Zhang W, Yang X, Liu Y, Liu L, Feng K, Zhang X, Yang S, Sun L, Yu M, Yang J, Li X, Hu W, Miao RQ, Zhu Y, Li L, Han J, Chen Y, Duan Y
British journal of pharmacology 2018 May;175(9):1486-1503
British journal of pharmacology 2018 May;175(9):1486-1503
SET1A-Mediated Mono-Methylation at K342 Regulates YAP Activation by Blocking Its Nuclear Export and Promotes Tumorigenesis.
Fang L, Teng H, Wang Y, Liao G, Weng L, Li Y, Wang X, Jin J, Jiao C, Chen L, Peng X, Chen J, Yang Y, Fang H, Han D, Li C, Jin X, Zhang S, Liu Z, Liu M, Wei Q, Liao L, Ge X, Zhao B, Zhou D, Qin HL, Zhou J, Wang P
Cancer cell 2018 Jul 9;34(1):103-118.e9
Cancer cell 2018 Jul 9;34(1):103-118.e9
Activation of hepatic Nogo-B receptor expression-A new anti-liver steatosis mechanism of statins.
Zhang W, Yang X, Chen Y, Hu W, Liu L, Zhang X, Liu M, Sun L, Liu Y, Yu M, Li X, Li L, Zhu Y, Miao QR, Han J, Duan Y
Biochimica et biophysica acta. Molecular and cell biology of lipids 2018 Feb;1863(2):177-190
Biochimica et biophysica acta. Molecular and cell biology of lipids 2018 Feb;1863(2):177-190
Ubiquitination Regulates the Proteasomal Degradation and Nuclear Translocation of the Fat Mass and Obesity-Associated (FTO) Protein.
Zhu T, Yong XLH, Xia D, Widagdo J, Anggono V
Journal of molecular biology 2018 Feb 2;430(3):363-371
Journal of molecular biology 2018 Feb 2;430(3):363-371
Baicalein protects human vitiligo melanocytes from oxidative stress through activation of NF-E2-related factor2 (Nrf2) signaling pathway.
Ma J, Li S, Zhu L, Guo S, Yi X, Cui T, He Y, Chang Y, Liu B, Li C, Jian Z
Free radical biology & medicine 2018 Dec;129:492-503
Free radical biology & medicine 2018 Dec;129:492-503
Hypoxia-Induced Mitogenic Factor Promotes Cardiac Hypertrophy via Calcium-Dependent and Hypoxia-Inducible Factor-1α Mechanisms.
Kumar S, Wang G, Liu W, Ding W, Dong M, Zheng N, Ye H, Liu J
Hypertension (Dallas, Tex. : 1979) 2018 Aug;72(2):331-342
Hypertension (Dallas, Tex. : 1979) 2018 Aug;72(2):331-342
DExD/H-Box Helicase 36 Signaling via Myeloid Differentiation Primary Response Gene 88 Contributes to NF-κB Activation to Type 2 Porcine Reproductive and Respiratory Syndrome Virus Infection.
Jing H, Zhou Y, Fang L, Ding Z, Wang D, Ke W, Chen H, Xiao S
Frontiers in immunology 2017;8:1365
Frontiers in immunology 2017;8:1365
PADI2-Mediated Citrullination Promotes Prostate Cancer Progression.
Wang L, Song G, Zhang X, Feng T, Pan J, Chen W, Yang M, Bai X, Pang Y, Yu J, Han J, Han B
Cancer research 2017 Nov 1;77(21):5755-5768
Cancer research 2017 Nov 1;77(21):5755-5768
Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20.
Liu G, Zhou L, Zhang H, Chen R, Zhang Y, Li L, Lu JY, Jiang H, Liu D, Qi S, Jiang YM, Yin K, Xie Z, Shi Y, Liu Y, Cao X, Chen YX, Zou D, Zhang WJ
Nature communications 2017 Mar 22;8:14824
Nature communications 2017 Mar 22;8:14824
ERK1/2-mediated Cytoplasmic Accumulation of hnRNPK Antagonizes TRAIL-induced Apoptosis through Upregulation of XIAP in H1299 Cells.
Huang WS, Xu FM, Zeng QZ, Liu XH, Gao XJ, Liu LX
Biomedical and environmental sciences : BES 2017 Jul;30(7):473-481
Biomedical and environmental sciences : BES 2017 Jul;30(7):473-481
Highly expressed lncRNA CCND2-AS1 promotes glioma cell proliferation through Wnt/β-catenin signaling.
Zhang H, Wei DL, Wan L, Yan SF, Sun YH
Biochemical and biophysical research communications 2017 Jan 22;482(4):1219-1225
Biochemical and biophysical research communications 2017 Jan 22;482(4):1219-1225
CRB3 regulates contact inhibition by activating the Hippo pathway in mammary epithelial cells.
Mao X, Li P, Wang Y, Liang Z, Liu J, Li J, Jiang Y, Bao G, Li L, Zhu B, Ren Y, Zhao X, Zhang J, Liu Y, Yang J, Liu P
Cell death & disease 2017 Jan 12;8(1):e2546
Cell death & disease 2017 Jan 12;8(1):e2546
TRAIL facilitates cytokine expression and macrophage migration during hypoxia/reoxygenation via ER stress-dependent NF-κB pathway.
Jiang Y, Chen X, Fan M, Li H, Zhu W, Chen X, Cao C, Xu R, Wang Y, Ma Y
Molecular immunology 2017 Feb;82:123-136
Molecular immunology 2017 Feb;82:123-136
TRIM52: A nuclear TRIM protein that positively regulates the nuclear factor-kappa B signaling pathway.
Fan W, Liu T, Li X, Zhou Y, Wu M, Cui X, Chen H, Qian P
Molecular immunology 2017 Feb;82:114-122
Molecular immunology 2017 Feb;82:114-122
Cluster of Differentiation 36 Deficiency Aggravates Macrophage Infiltration and Hepatic Inflammation by Upregulating Monocyte Chemotactic Protein-1 Expression of Hepatocytes Through Histone Deacetylase 2-Dependent Pathway.
Zhong S, Zhao L, Wang Y, Zhang C, Liu J, Wang P, Zhou W, Yang P, Varghese Z, Moorhead JF, Chen Y, Ruan XZ
Antioxidants & redox signaling 2017 Aug 1;27(4):201-214
Antioxidants & redox signaling 2017 Aug 1;27(4):201-214
Nuclear retention of the lncRNA SNHG1 by doxorubicin attenuates hnRNPC-p53 protein interactions.
Shen Y, Liu S, Fan J, Jin Y, Tian B, Zheng X, Fu H
EMBO reports 2017 Apr;18(4):536-548
EMBO reports 2017 Apr;18(4):536-548
CRB3 downregulation confers breast cancer stem cell traits through TAZ/β-catenin.
Li P, Wang Y, Mao X, Jiang Y, Liu J, Li J, Wang J, Wang R, She J, Zhang J, Yang J, Liu Y, Liu P
Oncogenesis 2017 Apr 24;6(4):e322
Oncogenesis 2017 Apr 24;6(4):e322
Biallelic SUN5 Mutations Cause Autosomal-Recessive Acephalic Spermatozoa Syndrome.
Zhu F, Wang F, Yang X, Zhang J, Wu H, Zhang Z, Zhang Z, He X, Zhou P, Wei Z, Gecz J, Cao Y
American journal of human genetics 2016 Oct 6;99(4):942-949
American journal of human genetics 2016 Oct 6;99(4):942-949
Dicer interacts with SIRT7 and regulates H3K18 deacetylation in response to DNA damaging agents.
Zhang PY, Li G, Deng ZJ, Liu LY, Chen L, Tang JZ, Wang YQ, Cao ST, Fang YX, Wen F, Xu Y, Chen X, Shi KQ, Li WF, Xie C, Tang KF
Nucleic acids research 2016 May 5;44(8):3629-42
Nucleic acids research 2016 May 5;44(8):3629-42
Set7 facilitates hepatitis C virus replication via enzymatic activity-dependent attenuation of the IFN-related pathway.
Han T, Wan Y, Wang J, Zhao P, Yuan Y, Wang L, She Y, Broering R, Lu M, Ye L, Zhu Y
Journal of immunology (Baltimore, Md. : 1950) 2015 Mar 15;194(6):2757-68
Journal of immunology (Baltimore, Md. : 1950) 2015 Mar 15;194(6):2757-68
miR-206 modulates lipopolysaccharide-mediated inflammatory cytokine production in human astrocytes.
Duan X, Zohaib A, Li Y, Zhu B, Ye J, Wan S, Xu Q, Song Y, Chen H, Cao S
Cellular signalling 2015 Jan;27(1):61-8
Cellular signalling 2015 Jan;27(1):61-8
Novel function of PITH domain-containing 1 as an activator of internal ribosomal entry site to enhance RUNX1 expression and promote megakaryocyte differentiation.
Lu B, Sun X, Chen Y, Jin Q, Liang Q, Liu S, Li Y, Zhou Y, Li W, Huang Z
Cellular and molecular life sciences : CMLS 2015 Feb;72(4):821-32
Cellular and molecular life sciences : CMLS 2015 Feb;72(4):821-32
Protective effect of astaxanthin on liver fibrosis through modulation of TGF-β1 expression and autophagy.
Shen M, Chen K, Lu J, Cheng P, Xu L, Dai W, Wang F, He L, Zhang Y, Chengfen W, Li J, Yang J, Zhu R, Zhang H, Zheng Y, Zhou Y, Guo C
Mediators of inflammation 2014;2014:954502
Mediators of inflammation 2014;2014:954502
FHL2-driven molecular network mediated Septin2 knockdown inducing apoptosis in mesangial cell.
Lu Y, Cai G, Cui S, Geng W, Chen D, Wen J, Zhang Y, Zhang F, Xie Y, Fu B, Chen X
Proteomics 2014 Nov;14(21-22):2485-97
Proteomics 2014 Nov;14(21-22):2485-97
Novel function of the chromosome 7 open reading frame 41 gene to promote leukemic megakaryocyte differentiation by modulating TPA-induced signaling.
Sun X, Lu B, Hu B, Xiao W, Li W, Huang Z
Blood cancer journal 2014 Mar 28;4:e198
Blood cancer journal 2014 Mar 28;4:e198
UDP-glucose dehydrogenase modulates proteoglycan synthesis in articular chondrocytes: its possible involvement and regulation in osteoarthritis.
Wen Y, Li J, Wang L, Tie K, Magdalou J, Chen L, Wang H
Arthritis research & therapy 2014 Dec 3;16(6):484
Arthritis research & therapy 2014 Dec 3;16(6):484
Proteomic analysis of primary duck hepatocytes infected with duck hepatitis B virus.
Zhao Y, Ben H, Qu S, Zhou X, Yan L, Xu B, Zhou S, Lou Q, Ye R, Zhou T, Yang P, Qu D
Proteome science 2010 Jun 7;8:28
Proteome science 2010 Jun 7;8:28
Proteomic analysis of protein complexes in human SH-SY5Y neuroblastoma cells by using blue-native gel electrophoresis: an increase in lamin A/C associated with heat shock protein 90 in response to 6-hydroxydopamine-induced oxidative stress.
Nakamura M, Morisawa H, Imajoh-Ohmi S, Takamura C, Fukuda H, Toda T
Experimental gerontology 2009 Jun-Jul;44(6-7):375-82
Experimental gerontology 2009 Jun-Jul;44(6-7):375-82
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 10298-1-AP(lamin-A antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using LMNA antibody 10298-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-lamin-A (IP:10298-1-AP, 3ug; Detection:10298-1-AP 1:1000) with A375 cells lysate 800ug.
- Sample type
- cell line
