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LearnMA1-06102
antibody from Invitrogen Antibodies
Targeting: LMNA
CMD1A, HGPS, LGMD1B, LMN1, LMNL1, MADA, PRO1
Western blot
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [3]
- Chromatin Immunoprecipitation [1]
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- Product number
- MA1-06102 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Lamin A/C Monoclonal Antibody (131C3)
- Antibody type
- Monoclonal
- Antigen
- Purifed from natural sources
- Description
- MA1-06102 detects lamin A and C in human, mouse, rat, bovine, hamster, sheep, and canine samples. MA1-06102 has sucessfully been used in immunocytochemistry, immunohistochemistry, FACs and Western blotting procedures. The MA1-06102 immunogen is purified rat liver lamins.
- Reactivity
- Human, Mouse, Rat, Bovine, Canine, Hamster
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 131C3
- Vial size
- 100 µg
- Concentration
- 1 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references Nuclear envelope rupture is induced by actin-based nucleus confinement.
Elevated PTEN levels account for the increased sensitivity of ethanol-exposed cells to tumor necrosis factor-induced cytotoxicity.
Hatch EM, Hetzer MW
The Journal of cell biology 2016 Oct 10;215(1):27-36
The Journal of cell biology 2016 Oct 10;215(1):27-36
Elevated PTEN levels account for the increased sensitivity of ethanol-exposed cells to tumor necrosis factor-induced cytotoxicity.
Shulga N, Hoek JB, Pastorino JG
The Journal of biological chemistry 2005 Mar 11;280(10):9416-24
The Journal of biological chemistry 2005 Mar 11;280(10):9416-24
No comments: Submit comment
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of Lamin A-C in human fibroblast lysate using Lamin A-C monoclonal antibody (Product # MA1-06102)
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunostaining of lamin A and C from human kidney using Product # MA1-06102.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemistry on frozen tissue section of human colon showing nuclear lamina staining in epithelial and connective tissue cells stained with Lamin A-C monoclonal antibody (Product # MA1-06102).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemistry analysis of Lamin A-C in frozen sections of swine skin using a Lamin A/C Monoclonal Antibody (131C3) (Product # MA1-06102), showing strong positive staining in nuclei of the epidermal cells and to a lesser extent in the connective tissue. Dilution 1:500.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemistry on frozen tissue section of human colon showing nuclear lamina staining in epithelial and connective tissue cells stained with Lamin A-C monoclonal antibody (Product # MA1-06102).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Chromatin Immunoprecipitation-Western Blot (ChIP-WB) of endogenous Lamin A/C proteins using Anti-Lamin A/C Antibody: ChIP was performed using Lamin A/C Mouse Monoclonal Antibody (Product # MA1-06102, 10 µg) (lane 2) on sheared chromatin from 4 million formaldehyde fixed HeLa cells. Normal Rabbit IgG (lane 1) was used as negative IP control. Western blot analysis of immunoprecipitated proteins was performed using Lamin A/C Mouse Monoclonal Antibody (Product # MA1-5820, 1:200 dilution).
