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LearnNB100-56649
antibody from Novus Biologicals
Targeting: LMNA
CMD1A, HGPS, LGMD1B, LMN1, LMNL1, MADA, PRO1
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Flow cytometry [1]
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- Product number
- NB100-56649 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-56649, RRID:AB_838524
- Product name
- Rabbit Polyclonal Lamin A + C Antibody
- Antibody type
- Polyclonal
- Description
- Unpurified. Because of immunogen's 100% homology with Isoforms 1, 4, 5, 6, ADelta10 and C of Prelamin-A/C, this antibody is expected to detect multiple bands in WB.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.2 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Proteasomal inhibition triggers viral oncoprotein degradation via autophagy-lysosomal pathway.
Laminopathy-inducing mutations reduce nuclear import of expressed prelamin A.
Phosphoproteomic profiling of human SH-SY5Y neuroblastoma cells during response to 6-hydroxydopamine-induced oxidative stress.
S/MAR-binding properties of Sox2 and its involvement in apoptosis of human NT2 neural precursors.
DBC2 significantly influences cell-cycle, apoptosis, cytoskeleton and membrane-trafficking pathways.
Gain C, Malik S, Bhattacharjee S, Ghosh A, Robertson ES, Das BB, Saha A
PLoS pathogens 2020 Feb;16(2):e1008105
PLoS pathogens 2020 Feb;16(2):e1008105
Laminopathy-inducing mutations reduce nuclear import of expressed prelamin A.
Kiel T, Busch A, Meyer-Rachner A, Hübner S
The international journal of biochemistry & cell biology 2014 Aug;53:271-80
The international journal of biochemistry & cell biology 2014 Aug;53:271-80
Phosphoproteomic profiling of human SH-SY5Y neuroblastoma cells during response to 6-hydroxydopamine-induced oxidative stress.
Nakamura M, Yamada M, Ohsawa T, Morisawa H, Nishine T, Nishimura O, Toda T
Biochimica et biophysica acta 2006 Sep;1763(9):977-89
Biochimica et biophysica acta 2006 Sep;1763(9):977-89
S/MAR-binding properties of Sox2 and its involvement in apoptosis of human NT2 neural precursors.
Lei JX, Liu QY, Sodja C, LeBlanc J, Ribecco-Lutkiewicz M, Smith B, Charlebois C, Walker PR, Sikorska M
Cell death and differentiation 2005 Nov;12(11):1368-77
Cell death and differentiation 2005 Nov;12(11):1368-77
DBC2 significantly influences cell-cycle, apoptosis, cytoskeleton and membrane-trafficking pathways.
Siripurapu V, Meth J, Kobayashi N, Hamaguchi M
Journal of molecular biology 2005 Feb 11;346(1):83-9
Journal of molecular biology 2005 Feb 11;346(1):83-9
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Lamin A + C Antibody [NB100-56649] - Analysis of human Lamin A + C in 15 ug of HeLa cell lysate using NB100-56649 at 1:1000.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow (Intracellular): Lamin A + C Antibody [NB100-56649] - Intracellular staining of HeLa cells (1 x 10^6 cells/mL) with Lamin A+C antibody (orange) stained at 1:1000. Detected with a GtxRb DyLight 488 secondary. Shown with the secondary only control (blue).
