Antibody data
- Antibody Data
- Antigen structure
- References [16]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 15841-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15841-1-AP, RRID:AB_2103801
- Product name
- Fibrinogen Gamma Chain antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Fibrinogen Gamma Chain antibody (Cat. #15841-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A novel missense mutation (FGG c.1168G > T) in the gamma chain of fibrinogen causing congenital hypodysfibrinogenemia with bleeding phenotype.
Identification of differentially expressed proteins in heart of mouse death from smother based on label-free proteomics.
Myelin Debris Impairs Tight Junctions and Promotes the Migration of Microvascular Endothelial Cells in the Injured Spinal Cord.
Tocilizumab promotes repair of spinal cord injury by facilitating the restoration of tight junctions between vascular endothelial cells.
Comparative Proteomics Reveals Prolonged Corneal Preservation Impaired Ocular Surface Immunity Accompanied by Fibrosis in Human Stroma.
Imatinib inhibits pericyte-fibroblast transition and inflammation and promotes axon regeneration by blocking the PDGF-BB/PDGFRβ pathway in spinal cord injury.
M1 macrophages impair tight junctions between endothelial cells after spinal cord injury.
Tear dynamics testing and quantitative proteomics analysis in patients with chronic renal failure.
Accelerated accumulation of fibrinogen peptide chains with Aβ deposition in Alzheimer's disease (AD) mice and human AD brains.
Integrated analysis reveals lung fibrinogen gamma chain as a biomarker for chronic obstructive pulmonary disease.
FTY720 Attenuates Neuropathic Pain after Spinal Cord Injury by Decreasing Systemic and Local Inflammation in a Rat Spinal Cord Compression Model.
C-reactive protein (CRP) recognizes uric acid crystals and recruits proteases C1 and MASP1.
Fibrinogen Chains Intrinsic to the Brain.
Quantitative iTRAQ-based proteomic analysis of piperine protected cerebral ischemia/reperfusion injury in rat brain.
Chronic liver injury drives non-traditional intrahepatic fibrin(ogen) crosslinking via tissue transglutaminase.
Fibrinogen β-derived Bβ(15-42) peptide protects against kidney ischemia/reperfusion injury.
Xu N, Zheng L, Dai Z, Zhu J, Xie P, Yang S, Chen F
Hereditas 2024 Jan 18;161(1):4
Hereditas 2024 Jan 18;161(1):4
Identification of differentially expressed proteins in heart of mouse death from smother based on label-free proteomics.
Zheng Z, Zhang L, Zhao C, Xiong H, Li J
Legal medicine (Tokyo, Japan) 2023 Nov;65:102302
Legal medicine (Tokyo, Japan) 2023 Nov;65:102302
Myelin Debris Impairs Tight Junctions and Promotes the Migration of Microvascular Endothelial Cells in the Injured Spinal Cord.
Yao F, Luo Y, Chen Y, Li Y, Hu X, You X, Li Z, Yu S, Tian D, Zheng M, Cheng L, Jing J
Cellular and molecular neurobiology 2023 Mar;43(2):741-756
Cellular and molecular neurobiology 2023 Mar;43(2):741-756
Tocilizumab promotes repair of spinal cord injury by facilitating the restoration of tight junctions between vascular endothelial cells.
Luo Y, Yao F, Shi Y, Zhu Z, Xiao Z, You X, Liu Y, Yu S, Tian D, Cheng L, Zheng M, Jing J
Fluids and barriers of the CNS 2023 Jan 9;20(1):1
Fluids and barriers of the CNS 2023 Jan 9;20(1):1
Comparative Proteomics Reveals Prolonged Corneal Preservation Impaired Ocular Surface Immunity Accompanied by Fibrosis in Human Stroma.
Wu PS, Liu HY, Wong TH, Lin JT, Hu FR, Lin MH
Journal of proteome research 2023 Dec 1;22(12):3730-3741
Journal of proteome research 2023 Dec 1;22(12):3730-3741
Imatinib inhibits pericyte-fibroblast transition and inflammation and promotes axon regeneration by blocking the PDGF-BB/PDGFRβ pathway in spinal cord injury.
Yao F, Luo Y, Liu YC, Chen YH, Li YT, Hu XY, You XY, Yu SS, Li ZY, Chen L, Tian DS, Zheng MG, Cheng L, Jing JH
Inflammation and regeneration 2022 Sep 26;42(1):44
Inflammation and regeneration 2022 Sep 26;42(1):44
M1 macrophages impair tight junctions between endothelial cells after spinal cord injury.
Luo Y, Yao F, Hu X, Li Y, Chen Y, Li Z, Zhu Z, Yu S, Tian D, Cheng L, Zheng M, Jing J
Brain research bulletin 2022 Mar;180:59-72
Brain research bulletin 2022 Mar;180:59-72
Tear dynamics testing and quantitative proteomics analysis in patients with chronic renal failure.
Zong RR, Zhu FF, Han W, Wang YX, Wang GL, Wang YZ, Mao YB, Guan TJ, Liu ZG, Xue YH, Li C
Journal of proteomics 2021 Sep 30;248:104351
Journal of proteomics 2021 Sep 30;248:104351
Accelerated accumulation of fibrinogen peptide chains with Aβ deposition in Alzheimer's disease (AD) mice and human AD brains.
Bian Z, Yamashita T, Shi X, Feng T, Yu H, Hu X, Hu X, Bian Y, Sun H, Tadokoro K, Takemoto M, Omote Y, Morihara R, Abe K
Brain research 2021 Sep 15;1767:147569
Brain research 2021 Sep 15;1767:147569
Integrated analysis reveals lung fibrinogen gamma chain as a biomarker for chronic obstructive pulmonary disease.
Zhang H, Li C, Song X, Cheng L, Liu Q, Zhang N, Wei L, Chung K, Adcock IM, Ling C, Li F
Annals of translational medicine 2021 Dec;9(24):1765
Annals of translational medicine 2021 Dec;9(24):1765
FTY720 Attenuates Neuropathic Pain after Spinal Cord Injury by Decreasing Systemic and Local Inflammation in a Rat Spinal Cord Compression Model.
Yamazaki K, Kawabori M, Seki T, Takamiya S, Tateno T, Konno K, Watanabe M, Houkin K
Journal of neurotrauma 2020 Aug 1;37(15):1720-1728
Journal of neurotrauma 2020 Aug 1;37(15):1720-1728
C-reactive protein (CRP) recognizes uric acid crystals and recruits proteases C1 and MASP1.
Alberts A, Klingberg A, Wessig AK, Combes C, Witte T, Brand K, Pich A, Neumann K
Scientific reports 2020 Apr 14;10(1):6391
Scientific reports 2020 Apr 14;10(1):6391
Fibrinogen Chains Intrinsic to the Brain.
Golanov EV, Sharpe MA, Regnier-Golanov AS, Del Zoppo GJ, Baskin DS, Britz GW
Frontiers in neuroscience 2019;13:541
Frontiers in neuroscience 2019;13:541
Quantitative iTRAQ-based proteomic analysis of piperine protected cerebral ischemia/reperfusion injury in rat brain.
Zou Y, Gong P, Zhao W, Zhang J, Wu X, Xin C, Xiong Z, Li Z, Wu X, Wan Q, Li X, Chen J
Neurochemistry international 2019 Mar;124:51-61
Neurochemistry international 2019 Mar;124:51-61
Chronic liver injury drives non-traditional intrahepatic fibrin(ogen) crosslinking via tissue transglutaminase.
Poole LG, Pant A, Baker KS, Kopec AK, Cline-Fedewa HM, Iismaa SE, Flick MJ, Luyendyk JP
Journal of thrombosis and haemostasis : JTH 2019 Jan;17(1):113-125
Journal of thrombosis and haemostasis : JTH 2019 Jan;17(1):113-125
Fibrinogen β-derived Bβ(15-42) peptide protects against kidney ischemia/reperfusion injury.
Krishnamoorthy A, Ajay AK, Hoffmann D, Kim TM, Ramirez V, Campanholle G, Bobadilla NA, Waikar SS, Vaidya VS
Blood 2011 Aug 18;118(7):1934-42
Blood 2011 Aug 18;118(7):1934-42
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human spleen tissue were subjected to SDS PAGE followed by western blot with 15841-1-AP(FGG antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Fibrinogen gamma chain antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Fibrinogen gamma chain. This antibody recognizes human,mouse,rat antigen. The Fibrinogen gamma chain antibody has been validated for the following applications: ELISA, WB, IHC analysis.