ABIN561009

antibody from antibodies-online

Targeting: GBA GBA1, GLUC

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN561009

Provider

antibodies-online

Product name

anti-Glucosidase, Beta, Acid (GBA) (AA 146-235) antibody

Antibody type

Monoclonal

Antigen

GBA (NP_000148, 146 a.a. ~ 235 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: SYFSEEGIGYNIIRVPMASC DFSIRTYTYADTPDDFQLHN FSLPEEDTKLKIPLIHRALQ LAQRPVSLLASPWTSPTWLK TNGAVNGKGS

Reactivity

Human

Host

Mouse

Epitope

AA 146-235

Isotype

IgG

Antibody clone number

2E2

Vial size

100 μg

Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References

Submitted references

Reduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson's disease.

Murphy KE, Gysbers AM, Abbott SK, Tayebi N, Kim WS, Sidransky E, Cooper A, Garner B, Halliday GM
Brain : a journal of neurology 2014 Mar;137(Pt 3):834-48

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Parkin-mediated ubiquitination of mutant glucocerebrosidase leads to competition with its substrates PARIS and ARTS.

Bendikov-Bar I, Rapaport D, Larisch S, Horowitz M
Orphanet journal of rare diseases 2014 Jun 16;9:86

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Gaucher disease paradigm: from ERAD to comorbidity.

Bendikov-Bar I, Horowitz M
Human mutation 2012 Oct;33(10):1398-407

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Characterization of the ERAD process of the L444P mutant glucocerebrosidase variant.

Bendikov-Bar I, Ron I, Filocamo M, Horowitz M
Blood cells, molecules & diseases 2011 Jan 15;46(1):4-10

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Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome.

Campeau PM, Rafei M, Boivin MN, Sun Y, Grabowski GA, Galipeau J
Blood 2009 Oct 8;114(15):3181-90