Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10245-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10245-1-AP, RRID:AB_2183801
- Product name
- S100A6 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated S100A6 antibody (Cat. #10245-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references c-Myc Upregulated by High Glucose Inhibits HaCaT Differentiation by S100A6 Transcriptional Activation.
Genetic screening of ANXA11 revealed novel mutations linked to amyotrophic lateral sclerosis.
Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function.
ZEB1 and IL-6/11-STAT3 signalling cooperate to define invasive potential of pancreatic cancer cells via differential regulation of the expression of S100 proteins.
Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis.
S100A6 promotes cell proliferation in human nasopharyngeal carcinoma via the p38/MAPK signaling pathway.
S100A6 as a potential serum prognostic biomarker and therapeutic target in gastric cancer.
Protein profiling the differences between diabetic and normal mouse cumulus cells.
Ca(2+) /S100 proteins regulate HCV virus NS5A-FKBP8/FKBP38 interaction and HCV virus RNA replication.
S100 proteins regulate the interaction of Hsp90 with Cyclophilin 40 and FKBP52 through their tetratricopeptide repeats.
Proteomic analysis of lung tissue of rats exposed to cigarette smoke and radon.
Radon-induced proteomic profile of lung tissue in rats.
Zhang J, Yang P, Liu D, Gao M, Wang J, Wang X, Liu Y, Zhang X
Frontiers in endocrinology 2021;12:676403
Frontiers in endocrinology 2021;12:676403
Genetic screening of ANXA11 revealed novel mutations linked to amyotrophic lateral sclerosis.
Teyssou E, Muratet F, Amador MD, Ferrien M, Lautrette G, Machat S, Boillée S, Larmonier T, Saker S, Leguern E, Cazeneuve C, Marie Y, Guegan J, Gyorgy B, Cintas P, Meininger V, Le Forestier N, Salachas F, Couratier P, Camu W, Seilhean D, Millecamps S
Neurobiology of aging 2021 Mar;99:102.e11-102.e20
Neurobiology of aging 2021 Mar;99:102.e11-102.e20
Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function.
Wang L, Yu P, Zhou B, Song J, Li Z, Zhang M, Guo G, Wang Y, Chen X, Han L, Hu S
Nature cell biology 2020 Jan;22(1):108-119
Nature cell biology 2020 Jan;22(1):108-119
ZEB1 and IL-6/11-STAT3 signalling cooperate to define invasive potential of pancreatic cancer cells via differential regulation of the expression of S100 proteins.
Al-Ismaeel Q, Neal CP, Al-Mahmoodi H, Almutairi Z, Al-Shamarti I, Straatman K, Jaunbocus N, Irvine A, Issa E, Moreman C, Dennison AR, Emre Sayan A, McDearmid J, Greaves P, Tulchinsky E, Kriajevska M
British journal of cancer 2019 Jul;121(1):65-75
British journal of cancer 2019 Jul;121(1):65-75
Mutations in the vesicular trafficking protein annexin A11 are associated with amyotrophic lateral sclerosis.
Smith BN, Topp SD, Fallini C, Shibata H, Chen HJ, Troakes C, King A, Ticozzi N, Kenna KP, Soragia-Gkazi A, Miller JW, Sato A, Dias DM, Jeon M, Vance C, Wong CH, de Majo M, Kattuah W, Mitchell JC, Scotter EL, Parkin NW, Sapp PC, Nolan M, Nestor PJ, Simpson M, Weale M, Lek M, Baas F, Vianney de Jong JM, Ten Asbroek ALMA, Redondo AG, Esteban-Pérez J, Tiloca C, Verde F, Duga S, Leigh N, Pall H, Morrison KE, Al-Chalabi A, Shaw PJ, Kirby J, Turner MR, Talbot K, Hardiman O, Glass JD, De Belleroche J, Maki M, Moss SE, Miller C, Gellera C, Ratti A, Al-Sarraj S, Brown RH Jr, Silani V, Landers JE, Shaw CE
Science translational medicine 2017 May 3;9(388)
Science translational medicine 2017 May 3;9(388)
S100A6 promotes cell proliferation in human nasopharyngeal carcinoma via the p38/MAPK signaling pathway.
Li A, Shi D, Xu B, Wang J, Tang YL, Xiao W, Shen G, Deng W, Zhao C
Molecular carcinogenesis 2017 Mar;56(3):972-984
Molecular carcinogenesis 2017 Mar;56(3):972-984
S100A6 as a potential serum prognostic biomarker and therapeutic target in gastric cancer.
Zhang J, Zhang K, Jiang X, Zhang J
Digestive diseases and sciences 2014 Sep;59(9):2136-44
Digestive diseases and sciences 2014 Sep;59(9):2136-44
Protein profiling the differences between diabetic and normal mouse cumulus cells.
Jiang GJ, Ma JY, Zhang GL, Mo FF, Zhang DW, Gao SH, Li XL
Molecular reproduction and development 2014 Dec;81(12):1080-5
Molecular reproduction and development 2014 Dec;81(12):1080-5
Ca(2+) /S100 proteins regulate HCV virus NS5A-FKBP8/FKBP38 interaction and HCV virus RNA replication.
Tani J, Shimamoto S, Mori K, Kato N, Moriishi K, Matsuura Y, Tokumitsu H, Tsuchiya M, Fujimoto T, Kato K, Miyoshi H, Masaki T, Kobayashi R
Liver international : official journal of the International Association for the Study of the Liver 2013 Aug;33(7):1008-18
Liver international : official journal of the International Association for the Study of the Liver 2013 Aug;33(7):1008-18
S100 proteins regulate the interaction of Hsp90 with Cyclophilin 40 and FKBP52 through their tetratricopeptide repeats.
Shimamoto S, Kubota Y, Tokumitsu H, Kobayashi R
FEBS letters 2010 Mar 19;584(6):1119-25
FEBS letters 2010 Mar 19;584(6):1119-25
Proteomic analysis of lung tissue of rats exposed to cigarette smoke and radon.
Xu NY, Zhang SP, Dong L, Nie JH, Tong J
Journal of toxicology and environmental health. Part A 2009;72(11-12):752-8
Journal of toxicology and environmental health. Part A 2009;72(11-12):752-8
Radon-induced proteomic profile of lung tissue in rats.
Xu NY, Zhang SP, Nie JH, Li JX, Tong J
Journal of toxicology and environmental health. Part A 2008;71(6):361-6
Journal of toxicology and environmental health. Part A 2008;71(6):361-6
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 10245-1-AP(S100A6 antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using S100A6 antibody 10245-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung cancer using 10245-1-AP(S100A6 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue