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- Antibody Data
- Antigen structure
- References [33]
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- Immunohistochemistry [1]
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- Product number
- NB300-101 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB300-101, RRID:AB_2200633
- Product name
- Rabbit Polyclonal NK1R Antibody
- Antibody type
- Polyclonal
- Description
- Unpurified. NB300-101 is specific to the NK-1 receptor. Specificity was verified by the localization of immunohistochemical staining with NB300-101 in the neurons of mouse brain tissue.
- Reactivity
- Human, Mouse, Rat, Guinea Pig
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Tachykinin upregulation in atopic dermatitis.
Neurokinin-1 receptor antagonism improves postoperative neurocognitive disorder in mice.
Botulinum toxin type A and gabapentin attenuate postoperative pain and NK1 receptor internalization in rats.
Hypoxia-induced increases in serotonin-immunoreactive nerve fibers in the medulla oblongata of the rat.
Antinociceptive effects of endomorphin-2: suppression of substance P release in the inflammatory pain model rat.
N-acetyl-L-tryptophan delays disease onset and extends survival in an amyotrophic lateral sclerosis transgenic mouse model.
Astrocytes in the rat nucleus tractus solitarii are critical for cardiovascular reflex control.
Substance P alterations in skin and brain of chronically stressed atopic-like mice.
Effects of four antitussives on airway neurogenic inflammation in a guinea pig model of chronic cough induced by cigarette smoke exposure.
Substance P participates in immune-mediated hepatic injury induced by concanavalin A in mice and stimulates cytokine synthesis in Kupffer cells.
Neurokinin-1 receptor, a new modulator of lymphangiogenesis in obese-asthma phenotype.
Sudden death and myocardial lesions after damage to catecholamine neurons of the nucleus tractus solitarii in rat.
Substance P receptor activation induces downregulation of the AMPA receptor functionality in cortical neurons from a genetic model of Amyotrophic Lateral Sclerosis.
Locally collateralizing glutamate neurons in the dorsal raphe nucleus responsive to substance P contain vesicular glutamate transporter 3 (VGLUT3).
Substance P provides neuroprotection in cerebellar granule cells through Akt and MAPK/Erk activation: evidence for the involvement of the delayed rectifier potassium current.
Expression of NK-1 and NK-3 tachykinin receptors in pancreatic acinar cells after acute experimental pancreatitis in rats.
Immunocytochemical distribution of NK-1 and NK-3 tachykinin receptors in isolated pancreatic acini of guinea pigs and rats.
A neurochemically distinct dorsal raphe-limbic circuit with a potential role in affective disorders.
The expression of neurokinin-1 receptor at striatal and pallidal levels in normal human brain.
The expression of neurokinin-1 receptor at striatal and pallidal levels in normal human brain.
Paraventricular vasopressin-containing neurons project to brain stem and spinal cord respiratory-related sites.
Paraventricular vasopressin-containing neurons project to brain stem and spinal cord respiratory-related sites.
Temporal decrease in renal sensory responses in rats after chronic ligation of the bile duct.
Localization of NK1 and NK3 receptors in guinea-pig brain.
Localization of NK1 and NK3 receptors in guinea-pig brain.
Phosphorylated cAMP response element binding protein increases in neurokinin-1 receptor-immunoreactive neurons in rat spinal cord in response to formalin-induced nociception.
Phosphorylated cAMP response element binding protein increases in neurokinin-1 receptor-immunoreactive neurons in rat spinal cord in response to formalin-induced nociception.
Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport.
Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport.
Localisation of tachykinin NK1 and NK3 receptors in the human prefrontal and visual cortex.
Localisation of tachykinin NK1 and NK3 receptors in the human prefrontal and visual cortex.
Neurokinin-1 receptor immunoreactivity in the nucleus of the solitary tract in the hamster.
Neurokinin-1 receptor immunoreactivity in the nucleus of the solitary tract in the hamster.
Lönndahl L, Rasul A, Lonne-Rahm SB, Holst M, Johansson B, El-Nour H, Radu Djurfeldt D, Nordlind K
Immunopharmacology and immunotoxicology 2019 Feb;41(1):117-122
Immunopharmacology and immunotoxicology 2019 Feb;41(1):117-122
Neurokinin-1 receptor antagonism improves postoperative neurocognitive disorder in mice.
Li Z, Luo T, Ning X, Xiong C, Wu A
Neuroscience letters 2018 Nov 20;687:189-195
Neuroscience letters 2018 Nov 20;687:189-195
Botulinum toxin type A and gabapentin attenuate postoperative pain and NK1 receptor internalization in rats.
Li X, Guo R, Sun Y, Li H, Ma D, Zhang C, Guan Y, Li J, Wang Y
Neurochemistry international 2018 Jun;116:52-62
Neurochemistry international 2018 Jun;116:52-62
Hypoxia-induced increases in serotonin-immunoreactive nerve fibers in the medulla oblongata of the rat.
Morinaga R, Nakamuta N, Yamamoto Y
Acta histochemica 2016 Oct;118(8):806-817
Acta histochemica 2016 Oct;118(8):806-817
Antinociceptive effects of endomorphin-2: suppression of substance P release in the inflammatory pain model rat.
Wu XN, Zhang T, Qian NS, Guo XD, Yang HJ, Huang KB, Luo GQ, Xiang W, Deng WT, Dai GH, Peng KR, Pan SY
Neurochemistry international 2015 Mar;82:1-9
Neurochemistry international 2015 Mar;82:1-9
N-acetyl-L-tryptophan delays disease onset and extends survival in an amyotrophic lateral sclerosis transgenic mouse model.
Li W, Fotinos A, Wu Q, Chen Y, Zhu Y, Baranov S, Tu Y, Zhou EW, Sinha B, Kristal BS, Wang X
Neurobiology of disease 2015 Aug;80:93-103
Neurobiology of disease 2015 Aug;80:93-103
Astrocytes in the rat nucleus tractus solitarii are critical for cardiovascular reflex control.
Lin LH, Moore SA, Jones SY, McGlashon J, Talman WT
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Nov 20;33(47):18608-17
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013 Nov 20;33(47):18608-17
Substance P alterations in skin and brain of chronically stressed atopic-like mice.
Grip L, Lonne-Rahm SB, Holst M, Johansson B, Nordlind K, Theodorsson E, El-Nour H
Journal of the European Academy of Dermatology and Venereology : JEADV 2013 Feb;27(2):199-205
Journal of the European Academy of Dermatology and Venereology : JEADV 2013 Feb;27(2):199-205
Effects of four antitussives on airway neurogenic inflammation in a guinea pig model of chronic cough induced by cigarette smoke exposure.
Luo YL, Li PB, Zhang CC, Zheng YF, Wang S, Nie YC, Zhang KJ, Su WW
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2013 Dec;62(12):1053-61
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2013 Dec;62(12):1053-61
Substance P participates in immune-mediated hepatic injury induced by concanavalin A in mice and stimulates cytokine synthesis in Kupffer cells.
Yang Y, Yan M, Zhang H, Wang X
Experimental and therapeutic medicine 2013 Aug;6(2):459-464
Experimental and therapeutic medicine 2013 Aug;6(2):459-464
Neurokinin-1 receptor, a new modulator of lymphangiogenesis in obese-asthma phenotype.
Ramalho R, Almeida J, Fernandes R, Costa R, Pirraco A, Guardão L, Delgado L, Moreira A, Soares R
Life sciences 2013 Aug 6;93(4):169-77
Life sciences 2013 Aug 6;93(4):169-77
Sudden death and myocardial lesions after damage to catecholamine neurons of the nucleus tractus solitarii in rat.
Talman WT, Dragon DN, Jones SY, Moore SA, Lin LH
Cellular and molecular neurobiology 2012 Oct;32(7):1119-26
Cellular and molecular neurobiology 2012 Oct;32(7):1119-26
Substance P receptor activation induces downregulation of the AMPA receptor functionality in cortical neurons from a genetic model of Amyotrophic Lateral Sclerosis.
Caioli S, Curcio L, Pieri M, Antonini A, Marolda R, Severini C, Zona C
Neurobiology of disease 2011 Oct;44(1):92-101
Neurobiology of disease 2011 Oct;44(1):92-101
Locally collateralizing glutamate neurons in the dorsal raphe nucleus responsive to substance P contain vesicular glutamate transporter 3 (VGLUT3).
Commons KG
Journal of chemical neuroanatomy 2009 Dec;38(4):273-81
Journal of chemical neuroanatomy 2009 Dec;38(4):273-81
Substance P provides neuroprotection in cerebellar granule cells through Akt and MAPK/Erk activation: evidence for the involvement of the delayed rectifier potassium current.
Amadoro G, Pieri M, Ciotti MT, Carunchio I, Canu N, Calissano P, Zona C, Severini C
Neuropharmacology 2007 May;52(6):1366-77
Neuropharmacology 2007 May;52(6):1366-77
Expression of NK-1 and NK-3 tachykinin receptors in pancreatic acinar cells after acute experimental pancreatitis in rats.
Broccardo M, Linari G, Agostini S, Amadoro G, Carpino F, Ciotti MT, Petrella C, Petrozza V, Severini C, Improta G
American journal of physiology. Gastrointestinal and liver physiology 2006 Sep;291(3):G518-24
American journal of physiology. Gastrointestinal and liver physiology 2006 Sep;291(3):G518-24
Immunocytochemical distribution of NK-1 and NK-3 tachykinin receptors in isolated pancreatic acini of guinea pigs and rats.
Broccardo M, Ciotti MT, Linari G, Agostini S, Petrella C, Amadoro G, Severini C, Improta G
Peptides 2005 Nov;26(11):2351-4
Peptides 2005 Nov;26(11):2351-4
A neurochemically distinct dorsal raphe-limbic circuit with a potential role in affective disorders.
Commons KG, Connolley KR, Valentino RJ
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003 Feb;28(2):206-15
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2003 Feb;28(2):206-15
The expression of neurokinin-1 receptor at striatal and pallidal levels in normal human brain.
Mounir S, Parent A
Neuroscience research 2002 Sep;44(1):71-81
Neuroscience research 2002 Sep;44(1):71-81
The expression of neurokinin-1 receptor at striatal and pallidal levels in normal human brain.
Mounir S, Parent A
Neuroscience research 2002 Sep;44(1):71-81
Neuroscience research 2002 Sep;44(1):71-81
Paraventricular vasopressin-containing neurons project to brain stem and spinal cord respiratory-related sites.
Kc P, Haxhiu MA, Tolentino-Silva FP, Wu M, Trouth CO, Mack SO
Respiratory physiology & neurobiology 2002 Oct 23;133(1-2):75-88
Respiratory physiology & neurobiology 2002 Oct 23;133(1-2):75-88
Paraventricular vasopressin-containing neurons project to brain stem and spinal cord respiratory-related sites.
Kc P, Haxhiu MA, Tolentino-Silva FP, Wu M, Trouth CO, Mack SO
Respiratory physiology & neurobiology 2002 Oct 23;133(1-2):75-88
Respiratory physiology & neurobiology 2002 Oct 23;133(1-2):75-88
Temporal decrease in renal sensory responses in rats after chronic ligation of the bile duct.
Ma MC, Huang HS, Chien CT, Wu MS, Chen CF
American journal of physiology. Renal physiology 2002 Jul;283(1):F164-72
American journal of physiology. Renal physiology 2002 Jul;283(1):F164-72
Localization of NK1 and NK3 receptors in guinea-pig brain.
Yip J, Chahl LA
Regulatory peptides 2001 Apr 2;98(1-2):55-62
Regulatory peptides 2001 Apr 2;98(1-2):55-62
Localization of NK1 and NK3 receptors in guinea-pig brain.
Yip J, Chahl LA
Regulatory peptides 2001 Apr 2;98(1-2):55-62
Regulatory peptides 2001 Apr 2;98(1-2):55-62
Phosphorylated cAMP response element binding protein increases in neurokinin-1 receptor-immunoreactive neurons in rat spinal cord in response to formalin-induced nociception.
Anderson LE, Seybold VS
Neuroscience letters 2000 Mar 31;283(1):29-32
Neuroscience letters 2000 Mar 31;283(1):29-32
Phosphorylated cAMP response element binding protein increases in neurokinin-1 receptor-immunoreactive neurons in rat spinal cord in response to formalin-induced nociception.
Anderson LE, Seybold VS
Neuroscience letters 2000 Mar 31;283(1):29-32
Neuroscience letters 2000 Mar 31;283(1):29-32
Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport.
Setou M, Nakagawa T, Seog DH, Hirokawa N
Science (New York, N.Y.) 2000 Jun 9;288(5472):1796-802
Science (New York, N.Y.) 2000 Jun 9;288(5472):1796-802
Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport.
Setou M, Nakagawa T, Seog DH, Hirokawa N
Science (New York, N.Y.) 2000 Jun 9;288(5472):1796-802
Science (New York, N.Y.) 2000 Jun 9;288(5472):1796-802
Localisation of tachykinin NK1 and NK3 receptors in the human prefrontal and visual cortex.
Tooney PA, Au GG, Chahl LA
Neuroscience letters 2000 Apr 14;283(3):185-8
Neuroscience letters 2000 Apr 14;283(3):185-8
Localisation of tachykinin NK1 and NK3 receptors in the human prefrontal and visual cortex.
Tooney PA, Au GG, Chahl LA
Neuroscience letters 2000 Apr 14;283(3):185-8
Neuroscience letters 2000 Apr 14;283(3):185-8
Neurokinin-1 receptor immunoreactivity in the nucleus of the solitary tract in the hamster.
Davis BJ, Smith HM
Neuroreport 1999 Apr 6;10(5):1003-6
Neuroreport 1999 Apr 6;10(5):1003-6
Neurokinin-1 receptor immunoreactivity in the nucleus of the solitary tract in the hamster.
Davis BJ, Smith HM
Neuroreport 1999 Apr 6;10(5):1003-6
Neuroreport 1999 Apr 6;10(5):1003-6
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: Neurokinin 1 Receptor Antibody [NB300-101] - Immunohistochemical analysis of Neurokinin 1 Receptor in mouse brain (selected cells, axon & dendrites) using NB300-101.
