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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [17]
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- Western blot [2]
- Immunohistochemistry [4]
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- Product number
- NBP2-24911 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal S100A7/Psoriasin Antibody
- Antibody type
- Monoclonal
- Description
- Protein G purified. In confluent MCF10A cells, an 11 kDa band is observed.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Placental transcriptomes in the common aneuploidies reveal critical regions on the trisomic chromosomes and genome-wide effects.
Expression of S100 protein family members in normal skin and sweat gland tumors.
The expression of Psoriasin (S100A7) and CD24 is linked and related to the differentiation of mammary epithelial cells.
Psoriasin (S100A7) increases the expression of ROS and VEGF and acts through RAGE to promote endothelial cell proliferation.
Expression and regulation of antimicrobial peptide psoriasin (S100A7) at the ocular surface and in the lacrimal apparatus.
S100A7/psoriasin expression in the human lung: unchanged in patients with COPD, but upregulated upon positive S. aureus detection.
Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1{alpha}, and TNF-{alpha} Recapitulates Some Features of Psoriasis.
Mammalian clock gene Cryptochrome regulates arthritis via proinflammatory cytokine TNF-alpha.
Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes.
Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes.
Chemotactic activity of S100A7 (Psoriasin) is mediated by the receptor for advanced glycation end products and potentiates inflammation with highly homologous but functionally distinct S100A15.
Chemotactic activity of S100A7 (Psoriasin) is mediated by the receptor for advanced glycation end products and potentiates inflammation with highly homologous but functionally distinct S100A15.
Expression patterns of S100A7 (psoriasin) and S100A9 (calgranulin-B) in keratinocyte differentiation.
IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes.
IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes.
Antimicrobial psoriasin (S100A7) protects human skin from Escherichia coli infection.
Molecular markers in ductal carcinoma in situ of the breast.
Bianco K, Gormley M, Farrell J, Zhou Y, Oliverio O, Tilden H, McMaster M, Fisher SJ
Prenatal diagnosis 2016 Sep;36(9):812-22
Prenatal diagnosis 2016 Sep;36(9):812-22
Expression of S100 protein family members in normal skin and sweat gland tumors.
Zhu L, Okano S, Takahara M, Chiba T, Tu Y, Oda Y, Furue M
Journal of dermatological science 2013 Jun;70(3):211-9
Journal of dermatological science 2013 Jun;70(3):211-9
The expression of Psoriasin (S100A7) and CD24 is linked and related to the differentiation of mammary epithelial cells.
Vegfors J, Petersson S, Kovács A, Polyak K, Enerbäck C
PloS one 2012;7(12):e53119
PloS one 2012;7(12):e53119
Psoriasin (S100A7) increases the expression of ROS and VEGF and acts through RAGE to promote endothelial cell proliferation.
Shubbar E, Vegfors J, Carlström M, Petersson S, Enerbäck C
Breast cancer research and treatment 2012 Jul;134(1):71-80
Breast cancer research and treatment 2012 Jul;134(1):71-80
Expression and regulation of antimicrobial peptide psoriasin (S100A7) at the ocular surface and in the lacrimal apparatus.
Garreis F, Gottschalt M, Schlorf T, Gläser R, Harder J, Worlitzsch D, Paulsen FP
Investigative ophthalmology & visual science 2011 Jul 1;52(7):4914-22
Investigative ophthalmology & visual science 2011 Jul 1;52(7):4914-22
S100A7/psoriasin expression in the human lung: unchanged in patients with COPD, but upregulated upon positive S. aureus detection.
Andresen E, Lange C, Strodthoff D, Goldmann T, Fischer N, Sahly H, Branscheid D, Heine H
BMC pulmonary medicine 2011 Feb 15;11:10
BMC pulmonary medicine 2011 Feb 15;11:10
Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1{alpha}, and TNF-{alpha} Recapitulates Some Features of Psoriasis.
Guilloteau K, Paris I, Pedretti N, Boniface K, Juchaux F, Huguier V, Guillet G, Bernard FX, Lecron JC, Morel F
Journal of immunology (Baltimore, Md. : 1950) 2010 May 1;184(9):5263-5270
Journal of immunology (Baltimore, Md. : 1950) 2010 May 1;184(9):5263-5270
Mammalian clock gene Cryptochrome regulates arthritis via proinflammatory cytokine TNF-alpha.
Hashiramoto A, Yamane T, Tsumiyama K, Yoshida K, Komai K, Yamada H, Yamazaki F, Doi M, Okamura H, Shiozawa S
Journal of immunology (Baltimore, Md. : 1950) 2010 Feb 1;184(3):1560-5
Journal of immunology (Baltimore, Md. : 1950) 2010 Feb 1;184(3):1560-5
Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes.
Pène J, Chevalier S, Preisser L, Vénéreau E, Guilleux MH, Ghannam S, Molès JP, Danger Y, Ravon E, Lesaux S, Yssel H, Gascan H
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 1;180(11):7423-30
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 1;180(11):7423-30
Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes.
Pène J, Chevalier S, Preisser L, Vénéreau E, Guilleux MH, Ghannam S, Molès JP, Danger Y, Ravon E, Lesaux S, Yssel H, Gascan H
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 1;180(11):7423-30
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 1;180(11):7423-30
Chemotactic activity of S100A7 (Psoriasin) is mediated by the receptor for advanced glycation end products and potentiates inflammation with highly homologous but functionally distinct S100A15.
Wolf R, Howard OM, Dong HF, Voscopoulos C, Boeshans K, Winston J, Divi R, Gunsior M, Goldsmith P, Ahvazi B, Chavakis T, Oppenheim JJ, Yuspa SH
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 15;181(2):1499-506
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 15;181(2):1499-506
Chemotactic activity of S100A7 (Psoriasin) is mediated by the receptor for advanced glycation end products and potentiates inflammation with highly homologous but functionally distinct S100A15.
Wolf R, Howard OM, Dong HF, Voscopoulos C, Boeshans K, Winston J, Divi R, Gunsior M, Goldsmith P, Ahvazi B, Chavakis T, Oppenheim JJ, Yuspa SH
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 15;181(2):1499-506
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 15;181(2):1499-506
Expression patterns of S100A7 (psoriasin) and S100A9 (calgranulin-B) in keratinocyte differentiation.
Martinsson H, Yhr M, Enerbäck C
Experimental dermatology 2005 Mar;14(3):161-8
Experimental dermatology 2005 Mar;14(3):161-8
IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes.
Boniface K, Bernard FX, Garcia M, Gurney AL, Lecron JC, Morel F
Journal of immunology (Baltimore, Md. : 1950) 2005 Mar 15;174(6):3695-702
Journal of immunology (Baltimore, Md. : 1950) 2005 Mar 15;174(6):3695-702
IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes.
Boniface K, Bernard FX, Garcia M, Gurney AL, Lecron JC, Morel F
Journal of immunology (Baltimore, Md. : 1950) 2005 Mar 15;174(6):3695-702
Journal of immunology (Baltimore, Md. : 1950) 2005 Mar 15;174(6):3695-702
Antimicrobial psoriasin (S100A7) protects human skin from Escherichia coli infection.
Gläser R, Harder J, Lange H, Bartels J, Christophers E, Schröder JM
Nature immunology 2005 Jan;6(1):57-64
Nature immunology 2005 Jan;6(1):57-64
Molecular markers in ductal carcinoma in situ of the breast.
Porter D, Lahti-Domenici J, Keshaviah A, Bae YK, Argani P, Marks J, Richardson A, Cooper A, Strausberg R, Riggins GJ, Schnitt S, Gabrielson E, Gelman R, Polyak K
Molecular cancer research : MCR 2003 Mar;1(5):362-75
Molecular cancer research : MCR 2003 Mar;1(5):362-75
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Simple Western: S100A7/Psoriasin Antibody (47C1068) - Azide Free [NBP2-24911] - Simple Western lane view shows a specific band for Psoriasin/S100A7 in 0.05 mg/ml of MCF-7 lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: S100A7/Psoriasin Antibody (47C1068) - Azide Free [NBP2-24911] - analysis of psoriasin in A) MCF10A and B) MCF7 cell lysate using psoriasin antibody at 1 ug/ml.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: S100A7/Psoriasin Antibody (47C1068) - Azide Free [NBP2-24911] - Analysis using Azide/BSA FREE version of NBP2-24911. IHC analysis of formalin-fixed paraffin-embedded tissue section of human esophageal squamous cell carcinoma (SCC) using 5 ug/ml concentration of Psoriasin/S100A7 antibody (clone 47C1068). Diffused to granular cytoplasmic immunostaining was observed all over the tissue section with highest expression levels in the areas with cancer cells especially in the developing squamous keratin pearls.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: S100A7/Psoriasin Antibody (47C1068) - Azide Free [NBP2-24911] - IHC analysis of formalin-fixed paraffin-embedded tissue section of human lymph node cancer using 5 ug/ml concentration of Psoriasin/S100A7 antibody (clone 47C1068). Very strong cytoplasmic immunopositivity of Psoriasin/S100A7 protein was observed in the cancer cells.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: S100A7/Psoriasin Antibody (47C1068) - Azide Free [NBP2-24911] - Formalin-fixed, paraffin-embedded human breast tissue stained with psoriasin antibody at 1:200 using peroxidase-conjugate and DAB chromogen. Antigen retrieval with citrate buffer, pH 6.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: S100A7/Psoriasin Antibody (47C1068) - Azide Free [NBP2-24911] - Staining of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
