Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- MAB1785 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB1785, RRID:AB_1711845
- Product name
- PGR (phospho S190) monoclonal antibody, clone 1154
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against synthetic phosphopeptide of PGR.
- Isotype
- IgG
- Antibody clone number
- 1154
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Regulation of signal transduction pathways by estrogen and progesterone.
Distinct molecular pathways mediate progesterone-induced growth inhibition and focal adhesion.
Differential hormone-dependent phosphorylation of progesterone receptor A and B forms revealed by a phosphoserine site-specific monoclonal antibody.
Edwards DP
Annual review of physiology 2005;67:335-76
Annual review of physiology 2005;67:335-76
Distinct molecular pathways mediate progesterone-induced growth inhibition and focal adhesion.
Lin VC, Woon CT, Aw SE, Guo C
Endocrinology 2003 Dec;144(12):5650-7
Endocrinology 2003 Dec;144(12):5650-7
Differential hormone-dependent phosphorylation of progesterone receptor A and B forms revealed by a phosphoserine site-specific monoclonal antibody.
Clemm DL, Sherman L, Boonyaratanakornkit V, Schrader WT, Weigel NL, Edwards DP
Molecular endocrinology (Baltimore, Md.) 2000 Jan;14(1):52-65
Molecular endocrinology (Baltimore, Md.) 2000 Jan;14(1):52-65
No comments: Submit comment
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot of whole cell T-47D lysate prepared from cells that had been inubated in the presence of the synthetic progestin agonist R5020 (500 nM) showing specific immunolabeling of the ~90k PGR-A isoform and the ~120 PGR-B isoform of the PGR phosphorylated at Ser190. The immunolabeling is specifically blocked by the phosphopeptide used as the antigen (not shown).