Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 10-7550-25 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-Galectin 13 Antibody
- Antibody type
- Monoclonal
- Description
- Galectin-13 (Gal-13) is a glycan-binding protein that regulates innate and adaptive immune responses. It is predominantly expressed by the syncytiotrophoblast and released from the placenta into the maternal circulation. It has the ability to induce apoptosis of activated T cells in vitro, and divert and kill T cells as well as macrophages in the maternal decidua. Gal-13 with its anti-inflammatory functions plays a role in regulation of maternal immune system, a lack of gal-13 contribute to an imbalance in inflammation processes in the placenta during pregnancy and therefore influences development of gestational diabetes mellitus (GDM). Gal-13 levels are low in the first trimester of pregnancy that confers a higher risk for developing pre-eclampsia later in pregnancy.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
A full length human Galectin-13 pro
tein was used as the immunogen for
this antibody.- Isotype
- IgG
- Antibody clone number
- ABM4E42
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
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Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of Galectin 13. Anti- Galectin 13 antibody (Clone: ABM4E42) was tested at 2.0 µg/ml on h Testis lysate.
- Protocol
- Protocol
Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of Galectin 13 in human placenta tissue using Galectin 13 antibody (Clone: ABM4E42) at 5 µg/ml.
- Protocol
- Protocol