Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS6896 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- REG3A polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human REG3A.
- Description
- The regeneration (REG) family consists of secretory proteins involved in liver, pancreatic, gastric and intestinal cell proliferation or differentiation. Members of the REG family are divided into four subclasses, designated types I, II, III and IV. They have been implicated in the regulation of cell growth, tumorigenesis and the progression of cancer. Specifically, increased expression of Reg IIIa results in pancreatic inflammation and liver carcinogenesis. Reg IIIa, also de-signated pancreatitis-associated protein, localizes to the apical region of pancreatic acinar cells and is similar to the C-type lectin superfamily. The Reg IIIa protein is mainly expressed in the intestine, with lower expression detected in healthy pancreas. It is also detected in pancreatic juice as a result of pancreatic inflammation.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- Western blot analysis of extracts of 293 cell lines, using REG3A antibody.