BS7845
antibody from Bioworld Technology, Inc
Targeting: NR5A2
B1F2, FTF, FTZ-F1, FTZ-F1beta, hB1F, hB1F-2, LRH-1, LRH1
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS7845 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- NR5A2 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human NR5A2.
- Description
- NR5A2 (nuclear receptor subfamily 5, group A, member 2), also designated B1-binding factor (B1F or B1F2), CYP7A promoter-binding factor (CPF), fetoprotein-alpha 1 (AFP) transcription factor (FTF, FTZ-F1 or FTZ-F1ÉÇ) and liver receptor homolog 1 (LRH-1), is a pre-adipocyte-specific nuclear receptor that regulates expression of aromatase in adipose tissue. NR5A2 belongs to the fushi tarazu factor-1 subfamily of orphan nuclear receptors. NR5A2 transcripts are abundant in the human ovary and testis and are predominantly expressed in tissues of endodermal origin. NR5A2 is a positive transcription factor for ABCG5 and ABCG8 and regulates genes involved in sterol and bile acid secretion from liver and intestine. It induces cell proliferation through the concomitant induction of cyclin D1 and E1, an effect that is potentiated by its interaction with ÉÇ-catenin.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- WesternBlot (WB) analysis of NR5A2 polyclonal antibody