Antibody data
- Antibody Data
- Antigen structure
- References [22]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 10194-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10194-1-AP, RRID:AB_2069179
- Product name
- CAPG antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CAPG antibody (Cat. #10194-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Tumor vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA): Suppresses macrophage capping protein beyond STING activation.
Integrative multi-omic profiling of adult mouse brain endothelial cells and potential implications in Alzheimer's disease.
A novel polypeptide CAPG-171aa encoded by circCAPG plays a critical role in triple-negative breast cancer.
Deposition of platelet-derived microparticles in podocytes contributes to diabetic nephropathy.
Facile discovery of red blood cell deformation and compromised membrane/skeleton assembly in Prader-Willi syndrome.
CAPG Is Required for Ebola Virus Infection by Controlling Virus Egress from Infected Cells.
Exogenous extracellular matrix proteins decrease cardiac fibroblast activation in stiffening microenvironment through CAPG.
Functional analysis of the CXCR1a gene response to SGIV viral infection in grouper.
Analysis of a Sardinian Multiplex Family with Autism Spectrum Disorder Points to Post-Synaptic Density Gene Variants and Identifies CAPG as a Functionally Relevant Candidate Gene.
Function of the macrophage-capping protein in colorectal carcinoma.
Effects of quercetin on the expression of MCP-1, MMP-9 and VEGF in rats with diabetic retinopathy.
Gelsolin-like actin-capping protein is associated with patient prognosis, cellular apoptosis and proliferation in prostate cancer.
Propofol Attenuates Lipopolysaccharide-Induced Monocyte Chemoattractant Protein-1 Production Through Enhancing apoM and foxa2 Expression in HepG2 Cells.
Acquisition of useful sero-diagnostic autoantibodies using the same patients'sera and tumor tissues.
Differential proteomic analysis of synovial fluid from rheumatoid arthritis and osteoarthritis patients.
Proteomic identification of the macrophage-capping protein as a protein contributing to the malignant features of hepatocellular carcinoma.
Laser microdissection and two-dimensional difference gel electrophoresis reveal the role of a novel macrophage-capping protein in lymph node metastasis in gastric cancer.
Macrophage-capping protein as a tissue biomarker for prediction of response to gemcitabine treatment and prognosis in cholangiocarcinoma.
Quantitative protein and mRNA profiling shows selective post-transcriptional control of protein expression by vasopressin in kidney cells.
Up-regulation of two actin-associated proteins prompts pulmonary artery smooth muscle cell migration under hypoxia.
Proteomics-based identification of two novel direct targets of hypoxia-inducible factor-1 and their potential roles in migration/invasion of cancer cells.
MnSOD marks cord blood late outgrowth endothelial cells and accompanies robust resistance to oxidative stress.
Xiao Z, Cui X, Liu F, Wang Y, Liu X, Zhou W, Zhang Y
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167149
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167149
Integrative multi-omic profiling of adult mouse brain endothelial cells and potential implications in Alzheimer's disease.
Yu M, Nie Y, Yang J, Yang S, Li R, Rao V, Hu X, Fang C, Li S, Song D, Guo F, Snyder MP, Chang HY, Kuo CJ, Xu J, Chang J
Cell reports 2023 Nov 28;42(11):113392
Cell reports 2023 Nov 28;42(11):113392
A novel polypeptide CAPG-171aa encoded by circCAPG plays a critical role in triple-negative breast cancer.
Song R, Guo P, Ren X, Zhou L, Li P, Rahman NA, Wołczyński S, Li X, Zhang Y, Liu M, Liu J, Li X
Molecular cancer 2023 Jul 5;22(1):104
Molecular cancer 2023 Jul 5;22(1):104
Deposition of platelet-derived microparticles in podocytes contributes to diabetic nephropathy.
Huang SJ, Zhang Y, Wang GH, Lu J, Chen PP, Zhang JX, Li XQ, Yuan BY, Liu XQ, Jiang TT, Wang MY, Liu WT, Ruan XZ, Liu BC, Ma KL
International urology and nephrology 2023 Feb;55(2):355-366
International urology and nephrology 2023 Feb;55(2):355-366
Facile discovery of red blood cell deformation and compromised membrane/skeleton assembly in Prader-Willi syndrome.
Yang Y, Li G, Wang Y, Sun Y, Xu C, Wei Z, Zhang S, Gao L, Liu S, Zhao J
Frontiers of medicine 2022 Dec;16(6):946-956
Frontiers of medicine 2022 Dec;16(6):946-956
CAPG Is Required for Ebola Virus Infection by Controlling Virus Egress from Infected Cells.
Mori H, Connell JP, Donahue CJ, Boytz R, Nguyen YTK, Leung DW, LaCount DJ, Davey RA
Viruses 2022 Aug 28;14(9)
Viruses 2022 Aug 28;14(9)
Exogenous extracellular matrix proteins decrease cardiac fibroblast activation in stiffening microenvironment through CAPG.
Wang X, Pierre V, Liu C, Senapati S, Park PS, Senyo SE
Journal of molecular and cellular cardiology 2021 Oct;159:105-119
Journal of molecular and cellular cardiology 2021 Oct;159:105-119
Functional analysis of the CXCR1a gene response to SGIV viral infection in grouper.
Wang Q, Yang M, Li C, Wang S, Wang Y, Lin F, Zheng L, Yu Y, Qin Q
Fish & shellfish immunology 2019 May;88:217-224
Fish & shellfish immunology 2019 May;88:217-224
Analysis of a Sardinian Multiplex Family with Autism Spectrum Disorder Points to Post-Synaptic Density Gene Variants and Identifies CAPG as a Functionally Relevant Candidate Gene.
Bacchelli E, Loi E, Cameli C, Moi L, Vega-Benedetti AF, Blois S, Fadda A, Bonora E, Mattu S, Fadda R, Chessa R, Maestrini E, Doneddu G, Zavattari P
Journal of clinical medicine 2019 Feb 7;8(2)
Journal of clinical medicine 2019 Feb 7;8(2)
Function of the macrophage-capping protein in colorectal carcinoma.
Wu W, Chen J, Ding Q, Yang S, Wang J, Yu H, Lin J
Oncology letters 2017 Nov;14(5):5549-5555
Oncology letters 2017 Nov;14(5):5549-5555
Effects of quercetin on the expression of MCP-1, MMP-9 and VEGF in rats with diabetic retinopathy.
Chen B, He T, Xing Y, Cao T
Experimental and therapeutic medicine 2017 Dec;14(6):6022-6026
Experimental and therapeutic medicine 2017 Dec;14(6):6022-6026
Gelsolin-like actin-capping protein is associated with patient prognosis, cellular apoptosis and proliferation in prostate cancer.
Li T, Hong X, Zhao J, Teng Y, Zheng J, Chen H, Chen H, Li H
Biomarkers in medicine 2016 Dec;10(12):1251-1260
Biomarkers in medicine 2016 Dec;10(12):1251-1260
Propofol Attenuates Lipopolysaccharide-Induced Monocyte Chemoattractant Protein-1 Production Through Enhancing apoM and foxa2 Expression in HepG2 Cells.
Ma X, Zhao JY, Zhao ZL, Ye J, Li SF, Fang HH, Gu MN, Hu YW, Qin ZS
Inflammation 2015;38(3):1329-36
Inflammation 2015;38(3):1329-36
Acquisition of useful sero-diagnostic autoantibodies using the same patients'sera and tumor tissues.
Kobayashi M, Nagashio R, Ryuge S, Murakami Y, Yanagita K, Nakashima H, Matsumoto T, Jiang SX, Saegusa M, Satoh Y, Masuda N, Sato Y
Biomedical research (Tokyo, Japan) 2014;35(2):133-43
Biomedical research (Tokyo, Japan) 2014;35(2):133-43
Differential proteomic analysis of synovial fluid from rheumatoid arthritis and osteoarthritis patients.
Balakrishnan L, Bhattacharjee M, Ahmad S, Nirujogi RS, Renuse S, Subbannayya Y, Marimuthu A, Srikanth SM, Raju R, Dhillon M, Kaur N, Jois R, Vasudev V, Ramachandra Y, Sahasrabuddhe NA, Prasad TsK, Mohan S, Gowda H, Shankar S, Pandey A
Clinical proteomics 2014 Jan 6;11(1):1
Clinical proteomics 2014 Jan 6;11(1):1
Proteomic identification of the macrophage-capping protein as a protein contributing to the malignant features of hepatocellular carcinoma.
Kimura K, Ojima H, Kubota D, Sakumoto M, Nakamura Y, Tomonaga T, Kosuge T, Kondo T
Journal of proteomics 2013 Jan 14;78:362-73
Journal of proteomics 2013 Jan 14;78:362-73
Laser microdissection and two-dimensional difference gel electrophoresis reveal the role of a novel macrophage-capping protein in lymph node metastasis in gastric cancer.
Ichikawa H, Kanda T, Kosugi S, Kawachi Y, Sasaki H, Wakai T, Kondo T
Journal of proteome research 2013 Aug 2;12(8):3780-91
Journal of proteome research 2013 Aug 2;12(8):3780-91
Macrophage-capping protein as a tissue biomarker for prediction of response to gemcitabine treatment and prognosis in cholangiocarcinoma.
Morofuji N, Ojima H, Onaya H, Okusaka T, Shimada K, Sakamoto Y, Esaki M, Nara S, Kosuge T, Asahina D, Ushigome M, Hiraoka N, Nagino M, Kondo T
Journal of proteomics 2012 Feb 16;75(5):1577-89
Journal of proteomics 2012 Feb 16;75(5):1577-89
Quantitative protein and mRNA profiling shows selective post-transcriptional control of protein expression by vasopressin in kidney cells.
Khositseth S, Pisitkun T, Slentz DH, Wang G, Hoffert JD, Knepper MA, Yu MJ
Molecular & cellular proteomics : MCP 2011 Jan;10(1):M110.004036
Molecular & cellular proteomics : MCP 2011 Jan;10(1):M110.004036
Up-regulation of two actin-associated proteins prompts pulmonary artery smooth muscle cell migration under hypoxia.
Zhang R, Zhou L, Li Q, Liu J, Yao W, Wan H
American journal of respiratory cell and molecular biology 2009 Oct;41(4):467-75
American journal of respiratory cell and molecular biology 2009 Oct;41(4):467-75
Proteomics-based identification of two novel direct targets of hypoxia-inducible factor-1 and their potential roles in migration/invasion of cancer cells.
Liao SH, Zhao XY, Han YH, Zhang J, Wang LS, Xia L, Zhao KW, Zheng Y, Guo M, Chen GQ
Proteomics 2009 Aug;9(15):3901-12
Proteomics 2009 Aug;9(15):3901-12
MnSOD marks cord blood late outgrowth endothelial cells and accompanies robust resistance to oxidative stress.
Cai H, Gehrig P, Scott TM, Zimmermann R, Schlapbach R, Zisch AH
Biochemical and biophysical research communications 2006 Nov 17;350(2):364-9
Biochemical and biophysical research communications 2006 Nov 17;350(2):364-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 10194-1-AP(CAPG antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using CAPG antibody 10194-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 10194-1-AP(CAPG antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue