HPA005456
antibody from Atlas Antibodies
Targeting: ARID1A
B120, BAF250, BAF250a, C10rf4, C1orf4, P270, SMARCF1
Antibody data
- Antibody Data
- Antigen structure
- References [91]
- Comments [0]
- Validations [0]
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Validation data
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- Product number
- HPA005456 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA005456, RRID:AB_1078205
- Product name
- Anti-ARID1A
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human ARID1A, Gene description: AT rich interactive domain 1A (SWI-like), Alternative Gene Names: B120, BAF250, BAF250a, C10rf4, C1orf4, P270, SMARCF1, Validated applications: WB, IHC, ICC, Uniprot ID: O14497, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.2 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references ARID1 and BRG1 Expression in Endometrial Cancer
ARID1A overexpression inhibits colorectal cancer cell migration through the regulation of epithelial‑mesenchymal transition
Proteomic insights into the regulatory function of ARID1A in colon cancer cells
ARID1A governs the silencing of sex-linked transcription during male meiosis in the mouse
Mitotic bookmarking by SWI/SNF subunits
Endothelial Arid1a deletion disrupts the balance among angiogenesis, neurogenesis and gliogenesis in the developing brain
Mixed Ovarian Neoplasms With Gastrointestinal-type Mucinous and Mullerian Epithelial Components
PPARα activator irbesartan suppresses the proliferation of endometrial carcinoma cells via SREBP1 and ARID1A
Abnormal chromatin remodeling caused by ARID1A deletion leads to malformation of the dentate gyrus
Comparison of the mutation patterns between tumor tissue and cell-free DNA in stage IV gastric cancer
Loss of ARID1A activates mTOR signaling and SOX9 in gastric adenocarcinoma—rationale for targeting ARID1A deficiency
Mullerian adenosarcoma: clinicopathologic and molecular characterization highlighting recurrent BAP1 loss and distinctive features of high-grade tumors
Treatment and outcomes in undifferentiated and dedifferentiated endometrial carcinoma
GLS1 is a Protective Factor in Patients with Ovarian Clear Cell Carcinoma and its Expression Does Not Correlate with ARID1A-mutated Tumors
Acetate supplementation restores cognitive deficits caused by ARID1A haploinsufficiency in excitatory neurons
Targeting USP9X–AMPK Axis in ARID1A-Deficient Hepatocellular Carcinoma
Multidimensional chromatin profiling of zebrafish pancreas to uncover and investigate disease-relevant enhancers
ARID1A loss induces polymorphonuclear myeloid-derived suppressor cell chemotaxis and promotes prostate cancer progression
Case report: Durable response after pembrolizumab in combination with radiation - induced abscopal effect in platinum - refractory metastatic endometrial clear cell carcinoma
Therapeutic targeting of ARID1A and PI3K/AKT pathway alterations in cholangiocarcinoma
mTORC1 Promotes ARID1A Degradation and Oncogenic Chromatin Remodeling in Hepatocellular Carcinoma
Arid1a regulates neural stem/progenitor cell proliferation and differentiation during cortical development
Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription
Endometrial Tumor Classification by Histomorphology and Biomarkers in the Nurses’ Health Study
Neo-Fs Index: A Novel Immunohistochemical Biomarker Panel Predicts Survival and Response to Anti-Angiogenetic Agents in Clear Cell Renal Cell Carcinoma
Downregulation of ARID1A is correlated with poor prognosis in non-small cell lung cancer
ARID1A alterations and their clinical significance in cholangiocarcinoma
SWI/SNF‐deficiency defines highly aggressive undifferentiated endometrial carcinoma
ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response
Atypical magnetic resonance imaging features and differential diagnosis of hepatocellular carcinoma
Endometrial Carcinomas with a “Serous” Component in Young Women Are Enriched for DNA Mismatch Repair Deficiency, Lynch Syndrome, and POLE Exonuclease Domain Mutations
Primary peritoneal clear cell carcinoma. A case report and literature review
Altered ARID1A expression in colorectal cancer
Establishment and characterization of VOA1066 cells: An undifferentiated endometrial carcinoma cell line
Loss of Arid1a Promotes Neuronal Survival Following Optic Nerve Injury
Inactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through transcriptional reprogramming
ARID1A protein expression is retained in ovarian endometriosis with ARID1A loss-of-function mutations: implication for the two-hit hypothesis
Dual ARID1A/ARID1B loss leads to rapid carcinogenesis and disruptive redistribution of BAF complexes
ARID1A upregulation predicts better survival in patients with urothelial bladder carcinoma
Iatrogenic endometriosis harbors somatic cancer-driver mutations
T cell-inflamed phenotype and increased Foxp3 expression in infiltrating T-cells of mismatch-repair deficient endometrial cancers
ARID1A prevents squamous cell carcinoma initiation and chemoresistance by antagonizing pRb/E2F1/c-Myc-mediated cancer stemness
FET family fusion oncoproteins target the SWI / SNF chromatin remodeling complex
BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design
Loss of Nuclear ARID-1A Expressions Is Associated with Hormone Receptor Status in Breast Cancers
Expression and significance of EBV, ARID1A and PIK3CA in gastric carcinoma
Alpha-oxoglutarate inhibits the proliferation of immortalized normal bladder epithelial cells via an epigenetic switch involving ARID1A
The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ
Tissue microarray is suitable for scientific biomarkers studies in endometrial cancer
Optimised ARID1A immunohistochemistry is an accurate predictor of ARID1A mutational status in gynaecological cancers
ARID1A mutation sensitizes most ovarian clear cell carcinomas to BET inhibitors
Intratumoral heterogeneity analysis reveals hidden associations between protein expression losses and patient survival in clear cell renal cell carcinoma
Systematic In Vivo Inactivation of Chromatin-Regulating Enzymes Identifies Setd2 as a Potent Tumor Suppressor in Lung Adenocarcinoma
Clear cell ovarian cancers with microsatellite instability: A unique subset of ovarian cancers with increased tumor-infiltrating lymphocytes and PD-1/PD-L1 expression
Cancer-Associated Mutations in Endometriosis without Cancer
Arid1a Has Context-Dependent Oncogenic and Tumor Suppressor Functions in Liver Cancer
Molecular-based classification algorithm for endometrial carcinoma categorizes ovarian endometrioid carcinoma into prognostically significant groups
Tracking the origin of simultaneous endometrial and ovarian cancer by next-generation sequencing – a case report
Epigenetic changes in localized gastric cancer: the role of RUNX3 in tumor progression and the immune microenvironment
ARID1A expression in early stage colorectal adenocarcinoma: an exploration of its prognostic significance
Inactivating ARID1A Tumor Suppressor Enhances TERT Transcription and Maintains Telomere Length in Cancer Cells
Concurrent ARID1A and ARID1B inactivation in endometrial and ovarian dedifferentiated carcinomas
Molecular genetic heterogeneity in undifferentiated endometrial carcinomas
Suppression of the SWI/SNF Component Arid1a Promotes Mammalian Regeneration
Immunohistochemistry Successfully Uncovers Intratumoral Heterogeneity and Widespread Co-Losses of Chromatin Regulators in Clear Cell Renal Cell Carcinoma
Altered expression of AT-rich interactive domain 1A in hepatocellular carcinoma.
Deregulation ofARID1A,CDH1,cMETandPIK3CAand target-related microRNA expression in gastric cancer
Immunohistochemical expression of ARID1A in penile squamous cell carcinomas: a tissue microarray study of 112 cases
Decreased expression of ARID1A associates with poor prognosis and promotes metastases of hepatocellular carcinoma
ARID1A expression in gastric adenocarcinoma: Clinicopathological significance and correlation with DNA mismatch repair status
Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers
Integrated Copy Number and Expression Analysis Identifies Profiles of Whole-Arm Chromosomal Alterations and Subgroups with Favorable Outcome in Ovarian Clear Cell Carcinomas
Increased proliferation in atypical hyperplasia/endometrioid intraepithelial neoplasia of the endometrium with concurrent inactivation of ARID1A and PTEN tumour suppressors
Application of ARID1A to murine formalin-fixed paraffin embedded tissue using immunohistochemistry
Loss of ARID1A expression and its relationship with PI3K-Akt pathway alterations and ZNF217 amplification in ovarian clear cell carcinoma
Frequent somatic mutations of the telomerase reverse transcriptase promoter in ovarian clear cell carcinoma but not in other major types of gynaecological malignancy
A functional proteogenomic analysis of endometrioid and clear cell carcinomas using reverse phase protein array and mutation analysis: protein expression is histotype-specific and loss of ARID1A/BAF250a is associated with AKT phosphorylation
Loss of ARID1A Expression Correlates With Stages of Tumor Progression in Uterine Endometrioid Carcinoma
Next-generation sequencing of endoscopic biopsies identifies ARID1A as a tumor-suppressor gene in Barrett’s esophagus
Loss of ARID1A/BAF250a expression in ovarian endometriosis and clear cell carcinoma.
Endocervical-type Mucinous Borderline Tumors are Related to Endometrioid Tumors Based on Mutation and Loss of Expression of ARID1A
Loss of ARID1A protein expression occurs as an early event in ovarian clear-cell carcinoma development and frequently coexists with PIK3CA mutations
Loss of ARID1A Expression Is an Early Molecular Event in Tumor Progression From Ovarian Endometriotic Cyst to Clear Cell and Endometrioid Carcinoma
Molecular Ontogeny of Donor-Derived Follicular Lymphomas Occurring after Hematopoietic Cell Transplantation
Functional Analysis of In-frame Indel ARID1A Mutations Reveals New Regulatory Mechanisms of Its Tumor Suppressor Functions
Functional analysis of in-frame indel ARID1A mutations reveals new regulatory mechanisms of its tumor suppressor functions.
PIK3CA mutations and loss of ARID1A protein expression are early events in the development of cystic ovarian clear cell adenocarcinoma
Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer
Mutation and Loss of Expression of ARID1A in Uterine Low-grade Endometrioid Carcinoma
KONTOMANOLIS E, SYMEONIDIS P, NIKOLETTOS K, PERROS P, RODY A, TSIKOURAS P, NIKOLETTOS N, GIATROMANOLAKI A
In Vivo 2024;38(3):1260-1265
In Vivo 2024;38(3):1260-1265
ARID1A overexpression inhibits colorectal cancer cell migration through the regulation of epithelial‑mesenchymal transition
Wanna‑Udom S, Aluksanasuwan S, Somsuan K, Mongkolwat W, Sakulsak N
Molecular Medicine Reports 2024;30(5)
Molecular Medicine Reports 2024;30(5)
Proteomic insights into the regulatory function of ARID1A in colon cancer cells
Aluksanasuwan S, Somsuan K, Wanna‑Udom S, Roytrakul S, Morchang A, Rongjumnong A, Sakulsak N
Oncology Letters 2024;28(2)
Oncology Letters 2024;28(2)
ARID1A governs the silencing of sex-linked transcription during male meiosis in the mouse
Menon D, Chakraborty P, Murcia N, Magnuson T
eLife 2024;12
eLife 2024;12
Mitotic bookmarking by SWI/SNF subunits
Zhu Z, Chen X, Guo A, Manzano T, Walsh P, Wills K, Halliburton R, Radko-Juettner S, Carter R, Partridge J, Green D, Zhang J, Roberts C
Nature 2023;618(7963):180-187
Nature 2023;618(7963):180-187
Endothelial Arid1a deletion disrupts the balance among angiogenesis, neurogenesis and gliogenesis in the developing brain
Wang Y, Su L, Wang W, Zhao J, Wang Y, Li S, Liu Y, Chai R, Li X, Teng Z, Liu C, Hu B, Ji F, Jiao J
Cell Proliferation 2023;56(5)
Cell Proliferation 2023;56(5)
Mixed Ovarian Neoplasms With Gastrointestinal-type Mucinous and Mullerian Epithelial Components
Chui M, Ellenson L
American Journal of Surgical Pathology 2023;47(7):756-765
American Journal of Surgical Pathology 2023;47(7):756-765
PPARα activator irbesartan suppresses the proliferation of endometrial carcinoma cells via SREBP1 and ARID1A
LU Y, MIYAMOTO T, TAKEUCHI H, TSUNODA F, TANAKA N, SHIOZAWA T
Oncology Research 2023;31(3):239-253
Oncology Research 2023;31(3):239-253
Abnormal chromatin remodeling caused by ARID1A deletion leads to malformation of the dentate gyrus
Liu P, Lu S, Li X, Tang G, Liu X, Dai S, Jiao L, Lin X, Li X, Hu B, Jiao J, Teng Z, Han C, Liu C
Cell Death & Differentiation 2023;30(9):2187-2199
Cell Death & Differentiation 2023;30(9):2187-2199
Comparison of the mutation patterns between tumor tissue and cell-free DNA in stage IV gastric cancer
Kung C, Fang W, Hung Y, Huang K, Chen M, Chao Y, Lin S, Li A, Lo S, Wu C
Aging 2023;15(3):777-790
Aging 2023;15(3):777-790
Simpkins F, Kinose Y, Xu H, Kim H, Kumar S, Shan X, Geroge E, Wang X, Medvedev S, Ferman B, Gitto S, Whicker M, D.Andrea K, Wubbenhorst B, Hallberg D, O'Connor M, Schwartz L, Hwang W, Nathanson K, Mills G, Velculescu V, Wang T, Brown E, Drapkin R
2023
2023
Loss of ARID1A activates mTOR signaling and SOX9 in gastric adenocarcinoma—rationale for targeting ARID1A deficiency
Dong X, Song S, Li Y, Fan Y, Wang L, Wang R, Huo L, Scott A, Xu Y, Pizzi M, Ma L, Wang Y, Jin J, Zhao W, Yao X, Johnson R, Wang L, Wang Z, Peng G, Ajani J
Gut 2022;71(3):467-478
Gut 2022;71(3):467-478
Mullerian adenosarcoma: clinicopathologic and molecular characterization highlighting recurrent BAP1 loss and distinctive features of high-grade tumors
Momeni Boroujeni A, Kertowidjojo E, Wu X, Soslow R, Chiang S, Da Silva E, Weigelt B, Chui M
Modern Pathology 2022;35(11):1684-1694
Modern Pathology 2022;35(11):1684-1694
Treatment and outcomes in undifferentiated and dedifferentiated endometrial carcinoma
Hamilton S, Tinker A, Kwon J, Lim P, Kong I, Sihra S, Koebel M, Lee C
Journal of Gynecologic Oncology 2022;33(3)
Journal of Gynecologic Oncology 2022;33(3)
GLS1 is a Protective Factor in Patients with Ovarian Clear Cell Carcinoma and its Expression Does Not Correlate with ARID1A-mutated Tumors
Clemente V, Hoshino A, Shetty M, Nelson A, Erickson B, Baker R, Rubin N, Khalifa M, Weroha S, Lou E, Bazzaro M
Cancer Research Communications 2022;2(8):784-794
Cancer Research Communications 2022;2(8):784-794
Acetate supplementation restores cognitive deficits caused by ARID1A haploinsufficiency in excitatory neurons
Liu P, Dai S, Mi T, Tang G, Wang Z, Wang H, Du H, Tang Y, Teng Z, Liu C
EMBO Molecular Medicine 2022;14(12)
EMBO Molecular Medicine 2022;14(12)
Targeting USP9X–AMPK Axis in ARID1A-Deficient Hepatocellular Carcinoma
Zhang F, Ni Q, Wang K, Cao H, Guan D, Zhang E, Ma N, Wang Y, Zheng Q, Xu S, Zhu B, Chen T, Xia J, Qiu X, Ding X, Jiang H, Qiu L, Wang X, Chen W, Cheng S, Xie D, Li J
Cellular and Molecular Gastroenterology and Hepatology 2022;14(1):101-127
Cellular and Molecular Gastroenterology and Hepatology 2022;14(1):101-127
Multidimensional chromatin profiling of zebrafish pancreas to uncover and investigate disease-relevant enhancers
Bordeira-Carriço R, Teixeira J, Duque M, Galhardo M, Ribeiro D, Acemel R, Firbas P, Tena J, Eufrásio A, Marques J, Ferreira F, Freitas T, Carneiro F, Goméz-Skarmeta J, Bessa J
Nature Communications 2022;13(1)
Nature Communications 2022;13(1)
ARID1A loss induces polymorphonuclear myeloid-derived suppressor cell chemotaxis and promotes prostate cancer progression
Li N, Liu Q, Han Y, Pei S, Cheng B, Xu J, Miao X, Pan Q, Wang H, Guo J, Wang X, Zhang G, Lian Y, Zhang W, Zang Y, Tan M, Li Q, Wang X, Xiao Y, Hu G, Jiang J, Huang H, Qin J
Nature Communications 2022;13(1)
Nature Communications 2022;13(1)
Case report: Durable response after pembrolizumab in combination with radiation - induced abscopal effect in platinum - refractory metastatic endometrial clear cell carcinoma
Kao C, Liu C, Lin H, Huang Y, Lan J, Ou Y, Fu H, Wu C
Frontiers in Immunology 2022;13
Frontiers in Immunology 2022;13
Therapeutic targeting of ARID1A and PI3K/AKT pathway alterations in cholangiocarcinoma
Tessiri S, Techasen A, Kongpetch S, Namjan A, Loilome W, Chan-on W, Thanan R, Jusakul A
PeerJ 2022;10
PeerJ 2022;10
mTORC1 Promotes ARID1A Degradation and Oncogenic Chromatin Remodeling in Hepatocellular Carcinoma
Zhang S, Zhou Y, Cao J, Burley S, Wang H, Zheng X
Cancer Research 2021;81(22):5652-5665
Cancer Research 2021;81(22):5652-5665
Arid1a regulates neural stem/progenitor cell proliferation and differentiation during cortical development
Liu X, Dai S, Liu P, Liu C
Cell Proliferation 2021;54(11)
Cell Proliferation 2021;54(11)
Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription
Blümli S, Wiechens N, Wu M, Singh V, Gierlinski M, Schweikert G, Gilbert N, Naughton C, Sundaramoorthy R, Varghese J, Gourlay R, Soares R, Clark D, Owen-Hughes T
Cell Reports 2021;37(5):109943
Cell Reports 2021;37(5):109943
Endometrial Tumor Classification by Histomorphology and Biomarkers in the Nurses’ Health Study
Watkins J, Downing M, Crous-Bou M, Busch E, Chen M, De Vivo I, Mutter G, Antwi S
Journal of Cancer Epidemiology 2021;2021
Journal of Cancer Epidemiology 2021;2021
Neo-Fs Index: A Novel Immunohistochemical Biomarker Panel Predicts Survival and Response to Anti-Angiogenetic Agents in Clear Cell Renal Cell Carcinoma
Kim J, Park J, Shin S, Lim B, Go H
Cancers 2021;13(6):1199
Cancers 2021;13(6):1199
Dedifferentiated Endometrioid Carcinomas with Neuroendocrine Differentiation: A Clinicopathological and Immunohistochemical Study of Three Cases
Zhou F, Zhang X, Chen H, Zheng W
Cancer Management and Research 2020;Volume 12
Cancer Management and Research 2020;Volume 12
Downregulation of ARID1A is correlated with poor prognosis in non-small cell lung cancer
Wang T, Guo J, Liu W, Guo Q, Cheng L, Zheng R, Hu X
Translational Cancer Research 2020;9(8):4896-4905
Translational Cancer Research 2020;9(8):4896-4905
ARID1A alterations and their clinical significance in cholangiocarcinoma
Namjan A, Techasen A, Loilome W, Sa-ngaimwibool P, Jusakul A
PeerJ 2020;8
PeerJ 2020;8
SWI/SNF‐deficiency defines highly aggressive undifferentiated endometrial carcinoma
Tessier‐Cloutier B, Coatham M, Carey M, Nelson G, Hamilton S, Lum A, Soslow R, Stewart C, Postovit L, Köbel M, Lee C
The Journal of Pathology: Clinical Research 2020;7(2):144-153
The Journal of Pathology: Clinical Research 2020;7(2):144-153
ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response
Nagarajan S, Rao S, Sutton J, Cheeseman D, Dunn S, Papachristou E, Prada J, Couturier D, Kumar S, Kishore K, Chilamakuri C, Glont S, Archer Goode E, Brodie C, Guppy N, Natrajan R, Bruna A, Caldas C, Russell A, Siersbæk R, Yusa K, Chernukhin I, Carroll J
Nature Genetics 2020;52(2):187-197
Nature Genetics 2020;52(2):187-197
Atypical magnetic resonance imaging features and differential diagnosis of hepatocellular carcinoma
Wang S, Yin L, Wang C, Ma M
Journal of International Medical Research 2020;48(10)
Journal of International Medical Research 2020;48(10)
Endometrial Carcinomas with a “Serous” Component in Young Women Are Enriched for DNA Mismatch Repair Deficiency, Lynch Syndrome, and POLE Exonuclease Domain Mutations
Conlon N, Da Cruz Paula A, Ashley C, Segura S, De Brot L, da Silva E, Soslow R, Weigelt B, DeLair D
American Journal of Surgical Pathology 2020;44(5):641-648
American Journal of Surgical Pathology 2020;44(5):641-648
Primary peritoneal clear cell carcinoma. A case report and literature review
Peiro G, Silva-Ortega S, Garcia-Espasa C, Sala-Ferichola M, Perez-Vicente S, Castellon-Molla E, Marcos-Sanmartin J
Gynecologic Oncology Reports 2020;32
Gynecologic Oncology Reports 2020;32
Altered ARID1A expression in colorectal cancer
Erfani M, Hosseini S, Mokhtari M, Zamani M, Tahmasebi K, Alizadeh Naini M, Taghavi A, Carethers J, Koi M, Brim H, Mokarram P, Ashktorab H
BMC Cancer 2020;20(1)
BMC Cancer 2020;20(1)
Establishment and characterization of VOA1066 cells: An undifferentiated endometrial carcinoma cell line
Christie E, Wang Y, Tao V, Shin C, Salamanca C, Chen S, Chow C, Köbel M, Ben-Neriah S, Farnell D, Steidl C, Mcalpine J, Gilks C, Huntsman D
PLOS ONE 2020;15(10):e0240412
PLOS ONE 2020;15(10):e0240412
Loss of Arid1a Promotes Neuronal Survival Following Optic Nerve Injury
Peng X, Dai S, Li C, Liu P, Wang Z, Du H, Teng Z, Yang S, Liu C
Frontiers in Cellular Neuroscience 2020;14
Frontiers in Cellular Neuroscience 2020;14
Inactivation of Arid1a in the endometrium is associated with endometrioid tumorigenesis through transcriptional reprogramming
Suryo Rahmanto Y, Shen W, Shi X, Chen X, Yu Y, Yu Z, Miyamoto T, Lee M, Singh V, Asaka R, Shimberg G, Vitolo M, Martin S, Wirtz D, Drapkin R, Xuan J, Wang T, Shih I
Nature Communications 2020;11(1)
Nature Communications 2020;11(1)
ARID1A protein expression is retained in ovarian endometriosis with ARID1A loss-of-function mutations: implication for the two-hit hypothesis
Yachida N, Yoshihara K, Suda K, Nakaoka H, Ueda H, Sugino K, Yamaguchi M, Mori Y, Yamawaki K, Tamura R, Ishiguro T, Isobe M, Motoyama T, Inoue I, Enomoto T
Scientific Reports 2020;10(1)
Scientific Reports 2020;10(1)
Dual ARID1A/ARID1B loss leads to rapid carcinogenesis and disruptive redistribution of BAF complexes
Wang Z, Chen K, Jia Y, Chuang J, Sun X, Lin Y, Celen C, Li L, Huang F, Liu X, Castrillon D, Wang T, Zhu H
Nature Cancer 2020;1(9):909-922
Nature Cancer 2020;1(9):909-922
ARID1A upregulation predicts better survival in patients with urothelial bladder carcinoma
Cao Q, Wang C, Ding Y, Xu D, Qian S, Shen H, Qi J
Journal of International Medical Research 2019;48(4)
Journal of International Medical Research 2019;48(4)
Iatrogenic endometriosis harbors somatic cancer-driver mutations
Lac V, Verhoef L, Aguirre-Hernandez R, Nazeran T, Tessier-Cloutier B, Praetorius T, Orr N, Noga H, Lum A, Khattra J, Prentice L, Co D, Köbel M, Mijatovic V, Lee A, Pasternak J, Bleeker M, Krämer B, Brucker S, Kommoss F, Kommoss S, Horlings H, Yong P, Huntsman D, Anglesio M
Human Reproduction 2019;34(1):69-78
Human Reproduction 2019;34(1):69-78
T cell-inflamed phenotype and increased Foxp3 expression in infiltrating T-cells of mismatch-repair deficient endometrial cancers
Asaka S, Yen T, Wang T, Shih I, Gaillard S
Modern Pathology 2019;32(4):576-584
Modern Pathology 2019;32(4):576-584
ARID1A prevents squamous cell carcinoma initiation and chemoresistance by antagonizing pRb/E2F1/c-Myc-mediated cancer stemness
Luo Q, Wu X, Chang W, Zhao P, Nan Y, Zhu X, Katz J, Su D, Liu Z
Cell Death & Differentiation 2019;27(6):1981-1997
Cell Death & Differentiation 2019;27(6):1981-1997
FET family fusion oncoproteins target the SWI / SNF chromatin remodeling complex
Lindén M, Thomsen C, Grundevik P, Jonasson E, Andersson D, Runnberg R, Dolatabadi S, Vannas C, Luna Santamarίa M, Fagman H, Ståhlberg A, Åman P
EMBO reports 2019;20(5)
EMBO reports 2019;20(5)
BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design
Farnaby W, Koegl M, Roy M, Whitworth C, Diers E, Trainor N, Zollman D, Steurer S, Karolyi-Oezguer J, Riedmueller C, Gmaschitz T, Wachter J, Dank C, Galant M, Sharps B, Rumpel K, Traxler E, Gerstberger T, Schnitzer R, Petermann O, Greb P, Weinstabl H, Bader G, Zoephel A, Weiss-Puxbaum A, Ehrenhöfer-Wölfer K, Wöhrle S, Boehmelt G, Rinnenthal J, Arnhof H, Wiechens N, Wu M, Owen-Hughes T, Ettmayer P, Pearson M, McConnell D, Ciulli A
Nature Chemical Biology 2019;15(7):672-680
Nature Chemical Biology 2019;15(7):672-680
Loss of Nuclear ARID-1A Expressions Is Associated with Hormone Receptor Status in Breast Cancers
Uncel M, Diniz G, Akoz G, Yildirim Ekin Z, Saydan S, Yardim S, Salimoglu S
European Journal of Breast Health 2019;15(2):125-129
European Journal of Breast Health 2019;15(2):125-129
Expression and significance of EBV, ARID1A and PIK3CA in gastric carcinoma
Zhou H, Tan S, Li H, Lin X
Molecular Medicine Reports 2019
Molecular Medicine Reports 2019
Alpha-oxoglutarate inhibits the proliferation of immortalized normal bladder epithelial cells via an epigenetic switch involving ARID1A
Shahid M, Gull N, Yeon A, Cho E, Bae J, Yoon H, You S, Yoon H, Kim M, Berman B, Kim J
Scientific Reports 2018;8(1)
Scientific Reports 2018;8(1)
The SWI/SNF complex is a mechanoregulated inhibitor of YAP and TAZ
Chang L, Azzolin L, Di Biagio D, Zanconato F, Battilana G, Lucon Xiccato R, Aragona M, Giulitti S, Panciera T, Gandin A, Sigismondo G, Krijgsveld J, Fassan M, Brusatin G, Cordenonsi M, Piccolo S
Nature 2018;563(7730):265-269
Nature 2018;563(7730):265-269
Tissue microarray is suitable for scientific biomarkers studies in endometrial cancer
Visser N, van der Wurff A, Pijnenborg J, Massuger L, Bulten J, Nagtegaal I
Virchows Archiv 2018;472(3):407-413
Virchows Archiv 2018;472(3):407-413
Optimised ARID1A immunohistochemistry is an accurate predictor of ARID1A mutational status in gynaecological cancers
Khalique S, Naidoo K, Attygalle A, Kriplani D, Daley F, Lowe A, Campbell J, Jones T, Hubank M, Fenwick K, Matthews N, Rust A, Lord C, Banerjee S, Natrajan R
The Journal of Pathology: Clinical Research 2018;4(3):154-166
The Journal of Pathology: Clinical Research 2018;4(3):154-166
ARID1A mutation sensitizes most ovarian clear cell carcinomas to BET inhibitors
Berns K, Caumanns J, Hijmans E, Gennissen A, Severson T, Evers B, Wisman G, Jan Meersma G, Lieftink C, Beijersbergen R, Itamochi H, van der Zee A, de Jong S, Bernards R
Oncogene 2018;37(33):4611-4625
Oncogene 2018;37(33):4611-4625
Intratumoral heterogeneity analysis reveals hidden associations between protein expression losses and patient survival in clear cell renal cell carcinoma
Jiang W, Dulaimi E, Devarajan K, Parsons T, Wang Q, O'Neill R, Solomides C, Peiper S, Testa J, Uzzo R, Yang H
Oncotarget 2017;8(23):37423-37434
Oncotarget 2017;8(23):37423-37434
Systematic In Vivo Inactivation of Chromatin-Regulating Enzymes Identifies Setd2 as a Potent Tumor Suppressor in Lung Adenocarcinoma
Walter D, Venancio O, Buza E, Tobias J, Deshpande C, Gudiel A, Kim-Kiselak C, Cicchini M, Yates T, Feldser D
Cancer Research 2017;77(7):1719-1729
Cancer Research 2017;77(7):1719-1729
Clear cell ovarian cancers with microsatellite instability: A unique subset of ovarian cancers with increased tumor-infiltrating lymphocytes and PD-1/PD-L1 expression
Howitt B, Strickland K, Sholl L, Rodig S, Ritterhouse L, Chowdhury D, D'Andrea A, Matulonis U, Konstantinopoulos P
OncoImmunology 2017;6(2):e1277308
OncoImmunology 2017;6(2):e1277308
Cancer-Associated Mutations in Endometriosis without Cancer
Anglesio M, Papadopoulos N, Ayhan A, Nazeran T, Noë M, Horlings H, Lum A, Jones S, Senz J, Seckin T, Ho J, Wu R, Lac V, Ogawa H, Tessier-Cloutier B, Alhassan R, Wang A, Wang Y, Cohen J, Wong F, Hasanovic A, Orr N, Zhang M, Popoli M, McMahon W, Wood L, Mattox A, Allaire C, Segars J, Williams C, Tomasetti C, Boyd N, Kinzler K, Gilks C, Diaz L, Wang T, Vogelstein B, Yong P, Huntsman D, Shih I
New England Journal of Medicine 2017;376(19):1835-1848
New England Journal of Medicine 2017;376(19):1835-1848
Arid1a Has Context-Dependent Oncogenic and Tumor Suppressor Functions in Liver Cancer
Sun X, Wang S, Wei Y, Luo X, Jia Y, Li L, Gopal P, Zhu M, Nassour I, Chuang J, Maples T, Celen C, Nguyen L, Wu L, Fu S, Li W, Hui L, Tian F, Ji Y, Zhang S, Sorouri M, Hwang T, Letzig L, James L, Wang Z, Yopp A, Singal A, Zhu H
Cancer Cell 2017;32(5):574-589.e6
Cancer Cell 2017;32(5):574-589.e6
Molecular-based classification algorithm for endometrial carcinoma categorizes ovarian endometrioid carcinoma into prognostically significant groups
Parra-Herran C, Lerner-Ellis J, Xu B, Khalouei S, Bassiouny D, Cesari M, Ismiil N, Nofech-Mozes S
Modern Pathology 2017;30(12):1748-1759
Modern Pathology 2017;30(12):1748-1759
Tracking the origin of simultaneous endometrial and ovarian cancer by next-generation sequencing – a case report
Valtcheva N, Lang F, Noske A, Samartzis E, Schmidt A, Bellini E, Fink D, Moch H, Rechsteiner M, Dedes K, Wild P
BMC Cancer 2017;17(1)
BMC Cancer 2017;17(1)
Epigenetic changes in localized gastric cancer: the role of RUNX3 in tumor progression and the immune microenvironment
Llorca-Cardeñosa M, Fleitas T, Ibarrola-Villava M, Peña-Chilet M, Mongort C, Martinez-Ciarpaglini C, Navarro L, Gambardella V, Castillo J, Roselló S, Navarro S, Ribas G, Cervantes A
Oncotarget 2016;7(39):63424-63436
Oncotarget 2016;7(39):63424-63436
ARID1A expression in early stage colorectal adenocarcinoma: an exploration of its prognostic significance
Lee L, Sadot E, Ivelja S, Vakiani E, Hechtman J, Sevinsky C, Klimstra D, Ginty F, Shia J
Human Pathology 2016;53
Human Pathology 2016;53
Inactivating ARID1A Tumor Suppressor Enhances TERT Transcription and Maintains Telomere Length in Cancer Cells
Rahmanto Y, Jung J, Wu R, Kobayashi Y, Heaphy C, Meeker A, Wang T, Shih I
Journal of Biological Chemistry 2016;291(18):9690-9699
Journal of Biological Chemistry 2016;291(18):9690-9699
Concurrent ARID1A and ARID1B inactivation in endometrial and ovarian dedifferentiated carcinomas
Coatham M, Li X, Karnezis A, Hoang L, Tessier-Cloutier B, Meng B, Soslow R, Blake Gilks C, Huntsman D, Stewart C, Postovit L, Köbel M, Lee C
Modern Pathology 2016;29(12):1586-1593
Modern Pathology 2016;29(12):1586-1593
Molecular genetic heterogeneity in undifferentiated endometrial carcinomas
Rosa-Rosa J, Leskelä S, Cristóbal-Lana E, Santón A, López-García M, Muñoz G, Pérez-Mies B, Biscuola M, Prat J, Esther O, Soslow R, Matias-Guiu X, Palacios J
Modern Pathology 2016;29(11):1390-1398
Modern Pathology 2016;29(11):1390-1398
Suppression of the SWI/SNF Component Arid1a Promotes Mammalian Regeneration
Sun X, Chuang J, Kanchwala M, Wu L, Celen C, Li L, Liang H, Zhang S, Maples T, Nguyen L, Wang S, Signer R, Sorouri M, Nassour I, Liu X, Xu J, Wu M, Zhao Y, Kuo Y, Wang Z, Xing C, Zhu H
Cell Stem Cell 2016;18(4):456-466
Cell Stem Cell 2016;18(4):456-466
Immunohistochemistry Successfully Uncovers Intratumoral Heterogeneity and Widespread Co-Losses of Chromatin Regulators in Clear Cell Renal Cell Carcinoma
Samant R, Jiang W, Dulaimi E, Devarajan K, Parsons T, Wang Q, Liao L, Cho E, O'Neill R, Solomides C, Peiper S, Testa J, Uzzo R, Yang H
PLOS ONE 2016;11(10):e0164554
PLOS ONE 2016;11(10):e0164554
Altered expression of AT-rich interactive domain 1A in hepatocellular carcinoma.
Abe H, Hayashi A, Kunita A, Sakamoto Y, Hasegawa K, Shibahara J, Kokudo N, Fukayama M
International journal of clinical and experimental pathology 2015;8(3):2763-70
International journal of clinical and experimental pathology 2015;8(3):2763-70
Deregulation ofARID1A,CDH1,cMETandPIK3CAand target-related microRNA expression in gastric cancer
Ibarrola-Villava M, Llorca-Cardeñosa M, Tarazona N, Mongort C, Fleitas T, Perez-Fidalgo J, Roselló S, Navarro S, Ribas G, Cervantes A
Oncotarget 2015;6(29):26935-26945
Oncotarget 2015;6(29):26935-26945
Immunohistochemical expression of ARID1A in penile squamous cell carcinomas: a tissue microarray study of 112 cases
Faraj S, Chaux A, Gonzalez-Roibon N, Munari E, Cubilla A, Shih I, Netto G
Human Pathology 2015;46(5):761-766
Human Pathology 2015;46(5):761-766
Decreased expression of ARID1A associates with poor prognosis and promotes metastases of hepatocellular carcinoma
He F, Li J, Xu J, Zhang S, Xu Y, Zhao W, Yin Z, Wang X
Journal of Experimental & Clinical Cancer Research 2015;34(1)
Journal of Experimental & Clinical Cancer Research 2015;34(1)
ARID1A expression in gastric adenocarcinoma: Clinicopathological significance and correlation with DNA mismatch repair status
Inada R, Sekine S, Taniguchi H, Tsuda H, Katai H, Fujiwara T, Kushima R
World Journal of Gastroenterology 2015;21(7):2159-2168
World Journal of Gastroenterology 2015;21(7):2159-2168
Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers
Bitler B, Aird K, Garipov A, Li H, Amatangelo M, Kossenkov A, Schultz D, Liu Q, Shih I, Conejo-Garcia J, Speicher D, Zhang R
Nature Medicine 2015;21(3):231-238
Nature Medicine 2015;21(3):231-238
Integrated Copy Number and Expression Analysis Identifies Profiles of Whole-Arm Chromosomal Alterations and Subgroups with Favorable Outcome in Ovarian Clear Cell Carcinomas
Müller R, Uehara Y, Oda K, Ikeda Y, Koso T, Tsuji S, Yamamoto S, Asada K, Sone K, Kurikawa R, Makii C, Hagiwara O, Tanikawa M, Maeda D, Hasegawa K, Nakagawa S, Wada-Hiraike O, Kawana K, Fukayama M, Fujiwara K, Yano T, Osuga Y, Fujii T, Aburatani H
PLOS ONE 2015;10(6):e0128066
PLOS ONE 2015;10(6):e0128066
Increased proliferation in atypical hyperplasia/endometrioid intraepithelial neoplasia of the endometrium with concurrent inactivation of ARID1A and PTEN tumour suppressors
Ayhan A, Mao T, Suryo Rahmanto Y, Zeppernick F, Ogawa H, Wu R, Wang T, Shih I
The Journal of Pathology: Clinical Research 2015;1(3):186-193
The Journal of Pathology: Clinical Research 2015;1(3):186-193
Application of ARID1A to murine formalin-fixed paraffin embedded tissue using immunohistochemistry
Howat W, Miller J, Gounaris I
F1000Research 2014;3
F1000Research 2014;3
Loss of ARID1A expression and its relationship with PI3K-Akt pathway alterations and ZNF217 amplification in ovarian clear cell carcinoma
Huang H, Lin M, Huang W, Chiang Y, Kuo K
Modern Pathology 2014;27(7):983-990
Modern Pathology 2014;27(7):983-990
Frequent somatic mutations of the telomerase reverse transcriptase promoter in ovarian clear cell carcinoma but not in other major types of gynaecological malignancy
Wu R, Ayhan A, Maeda D, Kim K, Clarke B, Shaw P, Chui M, Rosen B, Shih I, Wang T
The Journal of Pathology 2014;232(4):473-481
The Journal of Pathology 2014;232(4):473-481
A functional proteogenomic analysis of endometrioid and clear cell carcinomas using reverse phase protein array and mutation analysis: protein expression is histotype-specific and loss of ARID1A/BAF250a is associated with AKT phosphorylation
Wiegand K, Hennessy B, Leung S, Wang Y, Ju Z, McGahren M, Kalloger S, Finlayson S, Stemke-Hale K, Lu Y, Zhang F, Anglesio M, Gilks B, Mills G, Huntsman D, Carey M
BMC Cancer 2014;14(1)
BMC Cancer 2014;14(1)
Loss of ARID1A Expression Correlates With Stages of Tumor Progression in Uterine Endometrioid Carcinoma
Mao T, Ardighieri L, Ayhan A, Kuo K, Wu C, Wang T, Shih I
American Journal of Surgical Pathology 2013;37(9):1342-1348
American Journal of Surgical Pathology 2013;37(9):1342-1348
Next-generation sequencing of endoscopic biopsies identifies ARID1A as a tumor-suppressor gene in Barrett’s esophagus
Streppel M, Lata S, DelaBastide M, Montgomery E, Wang J, Canto M, Macgregor-Das A, Pai S, Morsink F, Offerhaus G, Antoniou E, Maitra A, McCombie W
Oncogene 2013;33(3):347-357
Oncogene 2013;33(3):347-357
Loss of ARID1A/BAF250a expression in ovarian endometriosis and clear cell carcinoma.
Xiao W, Awadallah A, Xin W
International journal of clinical and experimental pathology 2012;5(7):642-50
International journal of clinical and experimental pathology 2012;5(7):642-50
Endocervical-type Mucinous Borderline Tumors are Related to Endometrioid Tumors Based on Mutation and Loss of Expression of ARID1A
Wu C, Mao T, Vang R, Ayhan A, Wang T, Kurman R, Shih I
International Journal of Gynecological Pathology 2012;31(4):297-303
International Journal of Gynecological Pathology 2012;31(4):297-303
Loss of ARID1A protein expression occurs as an early event in ovarian clear-cell carcinoma development and frequently coexists with PIK3CA mutations
Yamamoto S, Tsuda H, Takano M, Tamai S, Matsubara O
Modern Pathology 2012;25(4):615-624
Modern Pathology 2012;25(4):615-624
Loss of ARID1A Expression Is an Early Molecular Event in Tumor Progression From Ovarian Endometriotic Cyst to Clear Cell and Endometrioid Carcinoma
Ayhan A, Mao T, Seckin T, Wu C, Guan B, Ogawa H, Futagami M, Mizukami H, Yokoyama Y, Kurman R, Shih I
International Journal of Gynecological Cancer 2012;22(8):1310-1315
International Journal of Gynecological Cancer 2012;22(8):1310-1315
Molecular Ontogeny of Donor-Derived Follicular Lymphomas Occurring after Hematopoietic Cell Transplantation
Weigert O, Kopp N, Lane A, Yoda A, Dahlberg S, Neuberg D, Bahar A, Chapuy B, Kutok J, Longtine J, Kuo F, Haley T, Salois M, Sullivan T, Fisher D, Fox E, Rodig S, Antin J, Weinstock D
Cancer Discovery 2012;2(1):47-55
Cancer Discovery 2012;2(1):47-55
Functional Analysis of In-frame Indel ARID1A Mutations Reveals New Regulatory Mechanisms of Its Tumor Suppressor Functions
Guan B, Gao M, Wu C, Wang T, Shih I
Neoplasia 2012;14(10):986-993
Neoplasia 2012;14(10):986-993
Functional analysis of in-frame indel ARID1A mutations reveals new regulatory mechanisms of its tumor suppressor functions.
Guan B, Gao M, Wu CH, Wang TL, Shih IeM
Neoplasia (New York, N.Y.) 2012 Oct;14(10):986-93
Neoplasia (New York, N.Y.) 2012 Oct;14(10):986-93
PIK3CA mutations and loss of ARID1A protein expression are early events in the development of cystic ovarian clear cell adenocarcinoma
Yamamoto S, Tsuda H, Takano M, Tamai S, Matsubara O
Virchows Archiv 2011;460(1):77-87
Virchows Archiv 2011;460(1):77-87
Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer
Wang K, Kan J, Yuen S, Shi S, Chu K, Law S, Chan T, Kan Z, Chan A, Tsui W, Lee S, Ho S, Chan A, Cheng G, Roberts P, Rejto P, Gibson N, Pocalyko D, Mao M, Xu J, Leung S
Nature Genetics 2011;43(12):1219-1223
Nature Genetics 2011;43(12):1219-1223
Mutation and Loss of Expression of ARID1A in Uterine Low-grade Endometrioid Carcinoma
Guan B, Mao T, Panuganti P, Kuhn E, Kurman R, Maeda D, Chen E, Jeng Y, Wang T, Shih I
American Journal of Surgical Pathology 2011;35(5):625-632
American Journal of Surgical Pathology 2011;35(5):625-632
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