HPA005457

antibody from Atlas Antibodies

Targeting: SEC31A ABP125, ABP130, KIAA0905, SEC31L1

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA005457

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA005457, RRID:AB_1079896

Product name

Anti-SEC31A

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human SEC31A, Gene description: SEC31 homolog A (S. cerevisiae), Alternative Gene Names: ABP125, ABP130, KIAA0905, SEC31L1, Validated applications: IHC, ICC, Uniprot ID: O94979, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.2 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

C9orf72-Associated Dipeptide Repeat Expansions Perturb ER-Golgi Vesicular Trafficking, Inducing Golgi Fragmentation and ER Stress, in ALS/FTD

Sultana J, Ragagnin A, Parakh S, Saravanabavan S, Soo K, Vidal M, Jagaraj C, Ding K, Wu S, Shadfar S, Don E, Deva A, Nicholson G, Rowe D, Blair I, Yang S, Atkin J
Molecular Neurobiology 2024;61(12):10318-10338

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Amyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress

Halloran M, Ragagnin A, Vidal M, Parakh S, Yang S, Heng B, Grima N, Shahheydari H, Soo K, Blair I, Guillemin G, Sundaramoorthy V, Atkin J
Cellular and Molecular Life Sciences 2019;77(19):3859-3873

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The TRAPP complex mediates secretion arrest induced by stress granule assembly

Zappa F, Wilson C, Di Tullio G, Santoro M, Pucci P, Monti M, D'Amico D, Pisonero‐Vaquero S, De Cegli R, Romano A, Saleem M, Polishchuk E, Failli M, Giaquinto L, De Matteis M
The EMBO Journal 2019;38(19)

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The role of the two splice variants and extranuclear pathway on Ki-67 regulation in non-cancer and cancer cells

Pal S, Chierico L, Rizzello L, Guan L, Joseph A, Lewis A, Battaglia G
PLOS ONE 2017;12(2):e0171815

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TMEM199 Deficiency Is a Disorder of Golgi Homeostasis Characterized by Elevated Aminotransferases, Alkaline Phosphatase, and Cholesterol and Abnormal Glycosylation

Jansen J, Timal S, van Scherpenzeel M, Michelakakis H, Vicogne D, Ashikov A, Moraitou M, Hoischen A, Huijben K, Steenbergen G, van den Boogert M, Porta F, Calvo P, Mavrikou M, Cenacchi G, van den Bogaart G, Salomon J, Holleboom A, Rodenburg R, Drenth J, Huynen M, Wevers R, Morava E, Foulquier F, Veltman J, Lefeber D
The American Journal of Human Genetics 2016;98(2):322-330

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CCDC115 Deficiency Causes a Disorder of Golgi Homeostasis with Abnormal Protein Glycosylation

Jansen J, Cirak S, van Scherpenzeel M, Timal S, Reunert J, Rust S, Pérez B, Vicogne D, Krawitz P, Wada Y, Ashikov A, Pérez-Cerdá C, Medrano C, Arnoldy A, Hoischen A, Huijben K, Steenbergen G, Quelhas D, Diogo L, Rymen D, Jaeken J, Guffon N, Cheillan D, van den Heuvel L, Maeda Y, Kaiser O, Schara U, Gerner P, van den Boogert M, Holleboom A, Nassogne M, Sokal E, Salomon J, van den Bogaart G, Drenth J, Huynen M, Veltman J, Wevers R, Morava E, Matthijs G, Foulquier F, Marquardt T, Lefeber D
The American Journal of Human Genetics 2016;98(2):310-321

Immunocytochemistry

Supportive validation

Submitted by

Atlas Antibodies (provider)

Main image

Experimental details

Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol & vesicles.

Sample type

Human