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Protein structure
DNTT
DNA nucleotidylexotransferaseTDT
This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| LSBio |  LS-C334595 |
Polyclonal |
WB
IHC
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| Invitrogen Antibodies | 17382-1-AP |
Polyclonal |
IP
IHC
FC
OA
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| Antibodies.com | A53047 |
Polyclonal |
WB
EL
ICC
IP
IHC
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| Proteintech Group | 17382-1-AP |
Polyclonal |
EL
IP
IHC
FC
|
||
| antibodies-online | ABIN5682922 |
Monoclonal |
WB
EL
IHC
FC
|
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