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- References [17]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 12716-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12716-1-AP, RRID:AB_2237551
- Product name
- PPID antibody
- Antibody type
- Polyclonal
- Description
- PPID antibody (Cat. #12716-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Hyaluronic Acid-Functionalized Bismuth Vanadate/Molybdenum Disulfide Nanoheterojunctions Achieve Efficient Phototherapy of Hypoxic Tumor.
Detection of PPID-interacting proteins in migraine rats by IP-MS and validation by bioinformatics analysis and experiments.
GPR43 regulates mitochondrial apoptosis through the cyclophilin D pathway in Alzheimer's disease.
Chaperone-mediated insertion of mitochondrial import receptor TOM70 protects against diet-induced obesity.
Porphyromonas gingivalis Induces Endothelial Dysfunction Through Sirt3-Dependent CypD Acetylation.
Extracellular vesicle-mediated delivery of circp53 suppresses the progression of multiple cancers by activating the CypD/TRAP/HSP90 pathway.
NR3C1/GLMN-Mediated FKBP12.6 Ubiquitination Disrupts Calcium Homeostasis and Impairs Mitochondrial Quality Control in Stress-Induced Myocardial Damage.
The Mechanism of a Novel Mitochondrial-Targeted Icaritin Derivative in Regulating Apoptosis of BEL-7402 Cells Based on the SIRT3 and CypD-Mediated ROS/p38 MAPK Signaling Pathway.
T-2 toxin induces mitochondrial dysfunction in chondrocytes via the p53-cyclophilin D pathway.
Bongkrekic acid alleviates airway inflammation via breaking the mPTP/mtDAMPs/RAGE feedback loop in a steroid-insensitive asthma model.
Reactive Oxygen Species Damage Bovine Endometrial Epithelial Cells via the Cytochrome C-mPTP Pathway.
Sensory nerves directly promote osteoclastogenesis by secreting peptidyl-prolyl cis-trans isomerase D (Cyp40).
Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome.
PM2.5-Induced Programmed Myocardial Cell Death via mPTP Opening Results in Deteriorated Cardiac Function in HFpEF Mice.
Downregulation of microRNA‑199a‑5p attenuates hypoxia/reoxygenation‑induced cytotoxicity in cardiomyocytes by targeting the HIF‑1α‑GSK3β‑mPTP axis.
A novel ent-kaurane diterpenoid analog, DN3, selectively kills human gastric cancer cells via acting directly on mitochondria.
Endothelial Monocyte-Activating Polypeptide-II Induces BNIP3-Mediated Mitophagy to Enhance Temozolomide Cytotoxicity of Glioma Stem Cells via Down-Regulating MiR-24-3p.
Pang Y, Guo J, Ma Q, Qi J, Liu L, Bu Y, Wang J
Biomaterials research 2025;29:0228
Biomaterials research 2025;29:0228
Detection of PPID-interacting proteins in migraine rats by IP-MS and validation by bioinformatics analysis and experiments.
Wang Y, Fu H, Zhao Y
Brain research 2025 Oct 15;1865:149854
Brain research 2025 Oct 15;1865:149854
GPR43 regulates mitochondrial apoptosis through the cyclophilin D pathway in Alzheimer's disease.
Wang X, Wu S, Deng Z, Yan M, Wang D, Yang M, Zhong F, Song J, Chen L, Chen Y, Tian Q, Yu W, Lü Y
Molecular medicine (Cambridge, Mass.) 2025 Jun 4;31(1):219
Molecular medicine (Cambridge, Mass.) 2025 Jun 4;31(1):219
Chaperone-mediated insertion of mitochondrial import receptor TOM70 protects against diet-induced obesity.
Latorre-Muro P, Vitale T, Ravichandran M, Zhang K, Palozzi JM, Bennett CF, Lamas-Paz A, Sohn JH, Jackson TD, Jedrychowski M, Gygi SP, Kajimura S, Schmoker A, Jeon H, Eck MJ, Puigserver P
Nature cell biology 2025 Jan;27(1):130-140
Nature cell biology 2025 Jan;27(1):130-140
Porphyromonas gingivalis Induces Endothelial Dysfunction Through Sirt3-Dependent CypD Acetylation.
Xu S, Zheng C, Huang J, Lu B, Que H, Xu L, Hou Y, He L, Fan X, Deng K, Hu R, Deng H, Wang Y
Journal of periodontal research 2025 Dec;60(12):1296-1307
Journal of periodontal research 2025 Dec;60(12):1296-1307
Extracellular vesicle-mediated delivery of circp53 suppresses the progression of multiple cancers by activating the CypD/TRAP/HSP90 pathway.
Yu X, Ding P, Guo M, Tang X, Wang Z, Zhang Y, Zhou L, Lv X, Shi H, Huang H, Mao J, Gu Z, Gu C, Yang Y
Experimental & molecular medicine 2025 Aug;57(8):1711-1726
Experimental & molecular medicine 2025 Aug;57(8):1711-1726
NR3C1/GLMN-Mediated FKBP12.6 Ubiquitination Disrupts Calcium Homeostasis and Impairs Mitochondrial Quality Control in Stress-Induced Myocardial Damage.
Cong J, Liu L, Shi R, He M, An Y, Feng X, Yin X, Li Y, Cong B, Shi W
International journal of molecular sciences 2025 Aug 25;26(17)
International journal of molecular sciences 2025 Aug 25;26(17)
The Mechanism of a Novel Mitochondrial-Targeted Icaritin Derivative in Regulating Apoptosis of BEL-7402 Cells Based on the SIRT3 and CypD-Mediated ROS/p38 MAPK Signaling Pathway.
Chen Z, Li W, Zhao Y, Liu D, Han J, Cai E
Molecules (Basel, Switzerland) 2025 Apr 8;30(8)
Molecules (Basel, Switzerland) 2025 Apr 8;30(8)
T-2 toxin induces mitochondrial dysfunction in chondrocytes via the p53-cyclophilin D pathway.
Yu FF, Yu SY, Sun L, Zuo J, Luo KT, Wang M, Fu XL, Zhang F, Huang H, Zhou GY, Wang YJ, Ba Y
Journal of hazardous materials 2024 Mar 5;465:133090
Journal of hazardous materials 2024 Mar 5;465:133090
Bongkrekic acid alleviates airway inflammation via breaking the mPTP/mtDAMPs/RAGE feedback loop in a steroid-insensitive asthma model.
Chen Y, Huang J, Li Y, Chen Y, Gong Z, Xu M, Ma Y, Hu D, Peng X, Xu G, Cai S, Liu L, Zhao W, Zhao H
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117111
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2024 Aug;177:117111
Reactive Oxygen Species Damage Bovine Endometrial Epithelial Cells via the Cytochrome C-mPTP Pathway.
Song P, Sun M, Liu C, Liu J, Lin P, Chen H, Zhou D, Tang K, Wang A, Jin Y
Antioxidants (Basel, Switzerland) 2023 Dec 16;12(12)
Antioxidants (Basel, Switzerland) 2023 Dec 16;12(12)
Sensory nerves directly promote osteoclastogenesis by secreting peptidyl-prolyl cis-trans isomerase D (Cyp40).
Li J, Liu B, Wu H, Zhang S, Liang Z, Guo S, Jiang H, Song Y, Lei X, Gao Y, Cheng P, Li D, Wang J, Liu Y, Wang D, Zhan N, Xu J, Wang L, Xiao G, Yang L, Pei G
Bone research 2023 Dec 14;11(1):64
Bone research 2023 Dec 14;11(1):64
Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome.
Geng J, Khaket TP, Pan J, Li W, Zhang Y, Ping Y, Cobos Sillero MI, Lu B
Developmental cell 2023 Apr 10;58(7):597-615.e10
Developmental cell 2023 Apr 10;58(7):597-615.e10
PM2.5-Induced Programmed Myocardial Cell Death via mPTP Opening Results in Deteriorated Cardiac Function in HFpEF Mice.
Wu T, Tong M, Chu A, Wu K, Niu X, Zhang Z
Cardiovascular toxicology 2022 Aug;22(8):746-762
Cardiovascular toxicology 2022 Aug;22(8):746-762
Downregulation of microRNA‑199a‑5p attenuates hypoxia/reoxygenation‑induced cytotoxicity in cardiomyocytes by targeting the HIF‑1α‑GSK3β‑mPTP axis.
Liu DW, Zhang YN, Hu HJ, Zhang PQ, Cui W
Molecular medicine reports 2019 Jun;19(6):5335-5344
Molecular medicine reports 2019 Jun;19(6):5335-5344
A novel ent-kaurane diterpenoid analog, DN3, selectively kills human gastric cancer cells via acting directly on mitochondria.
Ma YC, Zhu YL, Su N, Ke Y, Fan XX, Shi XJ, Liu HM, Wang AF
European journal of pharmacology 2019 Apr 5;848:11-22
European journal of pharmacology 2019 Apr 5;848:11-22
Endothelial Monocyte-Activating Polypeptide-II Induces BNIP3-Mediated Mitophagy to Enhance Temozolomide Cytotoxicity of Glioma Stem Cells via Down-Regulating MiR-24-3p.
Zhang J, Liu L, Xue Y, Ma Y, Liu X, Li Z, Li Z, Liu Y
Frontiers in molecular neuroscience 2018;11:92
Frontiers in molecular neuroscience 2018;11:92
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 12716-1-AP(PPID antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human cervical cancer using 12716-1-AP(PPID antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PPID antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PPID. This antibody recognizes human, mouse, rat antigen. The PPID antibody has been validated for the following applications: ELISA, WB, IHC analysis.
