67488-1-Ig

antibody from Proteintech Group

Targeting: SYVN1 DER3, HRD1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

67488-1-Ig

Provider

Proteintech Group

Product name

HRD1/SYVN1 antibody

Antibody type

Monoclonal

Description

HRD1/SYVN1 antibody (Cat. #67488-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, Mouse, Rat and has been validated for the following applications: IF, IHC, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

2C8A7

Vial size

20ul, 150ul

References

Submitted references

Stigmasterol upregulates Akt/mTOR/p70S6K signaling through SYVN1 to alleviate osteoporosis in ovariectomized rats.

Zhu F, Li W, Cao Y, Dai B, Wu H, Zhu Y, Liu H
European journal of nutrition 2026 Mar 26;65(3)

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p22(phox) prevents the oxidation of SERCA2a and stabilizes it in the heart.

Nakada Y, Titus AS, Mizushima W, Yang Y, Zhai P, Tian Y, Oka S, Kashihara T, Fefelova N, Pamarthi SH, Liu T, Li H, Xie LH, Takayama K, Ikeda S, Matsushita M, Huang CY, Hsu CP, Onoue K, Saito Y, Sadoshima J
Nature cardiovascular research 2025 Sep;4(9):1187-1205

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The Syvn1 inhibits neuronal cell ferroptosis by activating Stat3/Gpx4 axis in rat with spinal cord injury.

Xiao S, Zhang Y, Wang S, Liu J, Dan F, Yang F, Hong S, Liu N, Zeng Y, Huang K, Xie X, Zhong Y, Liu Z
Cell proliferation 2024 Oct;57(10):e13658

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Attenuation of renal fibrosis in mice due to lack of bombesin receptor-activated protein homologue.

Peng Z, Wang H, Zheng J, Chen H, Wang J, Weber HC, Yuan L, Qin X, Xiang Y, Liu C, Ji M, Liu H, Qu X
Clinical and experimental pharmacology & physiology 2024 Oct;51(10):e13916

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Quantitative proteomics reveals the mechanism of endoplasmic reticulum stress-mediated pulmonary fibrosis in mice.

Li H, Wang J, Li Z, Wu Z, Zhang Y, Kong L, Yang Q, Wang D, Shi H, Shen G, Zou S, Zhu W, Fan K, Xu Z
Heliyon 2024 Oct 30;10(20):e39150

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Circular RNA circARPC1B functions as a stabilisation enhancer of Vimentin to prevent high cholesterol-induced articular cartilage degeneration.

Li J, Li X, Zhou S, Wang Y, Ying T, Wang Q, Wu Y, Zhao F
Clinical and translational medicine 2023 Sep;13(9):e1415

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Down-regulation of Hrd1 protects against myocardial ischemia-reperfusion injury by regulating PPARα to prevent oxidative stress, endoplasmic reticulum stress, and cellular apoptosis.

Xia B, Li Q, Zheng K, Wu J, Huang C, Liu K, You Q, Yuan X
European journal of pharmacology 2023 Sep 5;954:175864

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UFMylation of HRD1 regulates endoplasmic reticulum homeostasis.

Luo H, Jiao QB, Shen CB, Gong WY, Yuan JH, Liu YY, Chen Z, Liu J, Xu XL, Cong YS, Zhang XW
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23221

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Integrative Proteomics and Transcriptomics Profiles of the Oviduct Reveal the Prolificacy-Related Candidate Biomarkers of Goats (Capra hircus) in Estrous Periods.

Sun Z, Liu Y, He X, Di R, Wang X, Ren C, Zhang Z, Chu M
International journal of molecular sciences 2022 Nov 28;23(23)

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S100A16 promotes acute kidney injury by activating HRD1-induced ubiquitination and degradation of GSK3β and CK1α.

Sun Y, Fan Y, Wang Z, Li M, Su D, Liu Y, Liang X
Cellular and molecular life sciences : CMLS 2022 Mar 12;79(3):184