Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 16209-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16209-1-AP, RRID:AB_2110874
- Product name
- GGCX antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GGCX antibody (Cat. #16209-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Molecular basis of vitamin-K-driven γ-carboxylation at the membrane interface.
Low phylloquinone intake deteriorates endothelial function in normolipidemic and dyslipidaemic mice.
GGCX promotes Eurasian avian-like H1N1 swine influenza virus adaption to interspecies receptor binding.
Assessment of gamma-glutamyl carboxylase activity in its native milieu.
The Ggcx(K325Q) Mutation Does Not Affect the Calcium Homeostasis of the Epididymis and Male Fertility in Mice.
Modification of Gas6 Protein in the Brain by a Functional Endogenous Tissue Vitamin K Cycle.
Vitamin K-dependent carboxylation regulates Ca(2+) flux and adaptation to metabolic stress in β cells.
Divergent effects of vitamins K1 and K2 on triple negative breast cancer cells.
VKOR paralog VKORC1L1 supports vitamin K-dependent protein carboxylation in vivo.
Functional Study of the Vitamin K Cycle Enzymes in Live Cells.
Characterization of vitamin K-dependent carboxylase mutations that cause bleeding and nonbleeding disorders.
GGCX and VKORC1 inhibit osteocalcin endocrine functions.
Cao Q, Ammerman A, Saimi M, Lin Z, Shen G, Chen H, Sun J, Chai M, Liu S, Hsu FF, Krezel AM, Gross ML, Xu J, Garcia BA, Liu B, Li W
Nature 2025 Mar;639(8055):816-824
Nature 2025 Mar;639(8055):816-824
Low phylloquinone intake deteriorates endothelial function in normolipidemic and dyslipidaemic mice.
Kij A, Kieronska-Rudek A, Bar A, Czyzynska-Cichon I, Strus M, Kozien L, Wiecek G, Zeber-Lubecka N, Kulecka M, Kwiatkowski G, Przyborowski K, Mohaissen T, Sternak M, Buczek E, Zakrzewska A, Proniewski B, Kus K, Franczyk-Zarow M, Kostogrys RB, Pieterman EJ, Princen HMG, Chlopicki S
The Journal of nutritional biochemistry 2025 Jun;140:109867
The Journal of nutritional biochemistry 2025 Jun;140:109867
GGCX promotes Eurasian avian-like H1N1 swine influenza virus adaption to interspecies receptor binding.
Zou J, Jiang M, Xiao R, Sun H, Liu H, Peacock T, Tu S, Chen T, Guo J, Zhao Y, Barclay W, Xie S, Zhou H
Nature communications 2025 Jan 15;16(1):670
Nature communications 2025 Jan 15;16(1):670
Assessment of gamma-glutamyl carboxylase activity in its native milieu.
Chen X, Stafford DW, Tie JK
Methods in enzymology 2024;708:207-236
Methods in enzymology 2024;708:207-236
The Ggcx(K325Q) Mutation Does Not Affect the Calcium Homeostasis of the Epididymis and Male Fertility in Mice.
Xiong M, Cheng P, Liu B, Zhao Y, Gao T, Li Z
Current issues in molecular biology 2024 May 22;46(6):5052-5065
Current issues in molecular biology 2024 May 22;46(6):5052-5065
Modification of Gas6 Protein in the Brain by a Functional Endogenous Tissue Vitamin K Cycle.
Aydin N, Ouliass B, Ferland G, Hafizi S
Cells 2024 May 18;13(10)
Cells 2024 May 18;13(10)
Vitamin K-dependent carboxylation regulates Ca(2+) flux and adaptation to metabolic stress in β cells.
Lacombe J, Guo K, Bonneau J, Faubert D, Gioanni F, Vivoli A, Muir SM, Hezzaz S, Poitout V, Ferron M
Cell reports 2023 May 30;42(5):112500
Cell reports 2023 May 30;42(5):112500
Divergent effects of vitamins K1 and K2 on triple negative breast cancer cells.
Beaudin S, Kokabee L, Welsh J
Oncotarget 2019 Mar 19;10(23):2292-2305
Oncotarget 2019 Mar 19;10(23):2292-2305
VKOR paralog VKORC1L1 supports vitamin K-dependent protein carboxylation in vivo.
Lacombe J, Rishavy MA, Berkner KL, Ferron M
JCI insight 2018 Jan 11;3(1)
JCI insight 2018 Jan 11;3(1)
Functional Study of the Vitamin K Cycle Enzymes in Live Cells.
Tie JK, Stafford DW
Methods in enzymology 2017;584:349-394
Methods in enzymology 2017;584:349-394
Characterization of vitamin K-dependent carboxylase mutations that cause bleeding and nonbleeding disorders.
Tie JK, Carneiro JD, Jin DY, Martinhago CD, Vermeer C, Stafford DW
Blood 2016 Apr 14;127(15):1847-55
Blood 2016 Apr 14;127(15):1847-55
GGCX and VKORC1 inhibit osteocalcin endocrine functions.
Ferron M, Lacombe J, Germain A, Oury F, Karsenty G
The Journal of cell biology 2015 Mar 16;208(6):761-76
The Journal of cell biology 2015 Mar 16;208(6):761-76
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 16209-1-AP(GGCX antibody) at dilution of 1:2000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 16209-1-AP(GGCX antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GGCX antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GGCX. This antibody recognizes human,mouse,rat antigen. The GGCX antibody has been validated for the following applications: ELISA, WB, IHC analysis.
