Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
Comment
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- Product number
- 16209-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16209-1-AP, RRID:AB_2110874
- Product name
- GGCX antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated GGCX antibody (Cat. #16209-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Vitamin K-dependent carboxylation regulates Ca(2+) flux and adaptation to metabolic stress in β cells.
Divergent effects of vitamins K1 and K2 on triple negative breast cancer cells.
VKOR paralog VKORC1L1 supports vitamin K-dependent protein carboxylation in vivo.
Functional Study of the Vitamin K Cycle Enzymes in Live Cells.
Characterization of vitamin K-dependent carboxylase mutations that cause bleeding and nonbleeding disorders.
GGCX and VKORC1 inhibit osteocalcin endocrine functions.
Lacombe J, Guo K, Bonneau J, Faubert D, Gioanni F, Vivoli A, Muir SM, Hezzaz S, Poitout V, Ferron M
Cell reports 2023 May 30;42(5):112500
Cell reports 2023 May 30;42(5):112500
Divergent effects of vitamins K1 and K2 on triple negative breast cancer cells.
Beaudin S, Kokabee L, Welsh J
Oncotarget 2019 Mar 19;10(23):2292-2305
Oncotarget 2019 Mar 19;10(23):2292-2305
VKOR paralog VKORC1L1 supports vitamin K-dependent protein carboxylation in vivo.
Lacombe J, Rishavy MA, Berkner KL, Ferron M
JCI insight 2018 Jan 11;3(1)
JCI insight 2018 Jan 11;3(1)
Functional Study of the Vitamin K Cycle Enzymes in Live Cells.
Tie JK, Stafford DW
Methods in enzymology 2017;584:349-394
Methods in enzymology 2017;584:349-394
Characterization of vitamin K-dependent carboxylase mutations that cause bleeding and nonbleeding disorders.
Tie JK, Carneiro JD, Jin DY, Martinhago CD, Vermeer C, Stafford DW
Blood 2016 Apr 14;127(15):1847-55
Blood 2016 Apr 14;127(15):1847-55
GGCX and VKORC1 inhibit osteocalcin endocrine functions.
Ferron M, Lacombe J, Germain A, Oury F, Karsenty G
The Journal of cell biology 2015 Mar 16;208(6):761-76
The Journal of cell biology 2015 Mar 16;208(6):761-76
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 16209-1-AP(GGCX antibody) at dilution of 1:2000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 16209-1-AP(GGCX antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The GGCX antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GGCX. This antibody recognizes human,mouse,rat antigen. The GGCX antibody has been validated for the following applications: ELISA, WB, IHC analysis.