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- References [17]
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- Product number
- 23865-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- USP39 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated USP39 antibody (Cat. #23865-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Histone lactylation promotes malignant progression by facilitating USP39 expression to target PI3K/AKT/HIF-1α signal pathway in endometrial carcinoma.
Lactate modulates RNA splicing to promote CTLA-4 expression in tumor-infiltrating regulatory T cells.
USP39-Mediated Non-Proteolytic Control of ETS2 Suppresses Nuclear Localization and Activity.
Lysine 2-hydroxyisobutyrylation of NAT10 promotes cancer metastasis in an ac4C-dependent manner.
USP39 facilitates breast cancer cell proliferation through stabilization of FOXM1.
DNAAF5 promotes hepatocellular carcinoma malignant progression by recruiting USP39 to improve PFKL protein stability.
The Deubiquitinase USP39 Promotes Esophageal Squamous Cell Carcinoma Malignancy as a Splicing Factor.
Ubiquitin-specific peptidase 39 promotes human glioma cells migration and invasion by facilitating ADAM9 mRNA maturation.
The LINC00623/NAT10 signaling axis promotes pancreatic cancer progression by remodeling ac4C modification of mRNA.
MiR-1281, a p53-responsive microRNA, impairs the survival of human osteosarcoma cells upon ER stress via targeting USP39.
Identification of a 35S U4/U6.U5 tri-small nuclear ribonucleoprotein (tri-snRNP) complex intermediate in spliceosome assembly.
Knockdown of ubiquitin-specific peptidase 39 inhibited the growth of osteosarcoma cells and induced apoptosis in vitro.
Knockdown of USP39 by lentivirus-mediated RNA interference suppresses the growth of oral squamous cell carcinoma.
Ubiquitin-specific protease 39 is overexpressed in human lung cancer and promotes tumor cell proliferation in vitro.
Lentivirus-mediated inhibition of USP39 suppresses the growth of gastric cancer cells via PARP activation.
Overexpression of USP39 predicts poor prognosis and promotes tumorigenesis of prostate cancer via promoting EGFR mRNA maturation and transcription elongation.
Reduced USP39 expression inhibits malignant proliferation of medullary thyroid carcinoma in vitro.
Wei S, Zhang J, Zhao R, Shi R, An L, Yu Z, Zhang Q, Zhang J, Yao Y, Li H, Wang H
Cell death discovery 2024 Mar 8;10(1):121
Cell death discovery 2024 Mar 8;10(1):121
Lactate modulates RNA splicing to promote CTLA-4 expression in tumor-infiltrating regulatory T cells.
Ding R, Yu X, Hu Z, Dong Y, Huang H, Zhang Y, Han Q, Ni ZY, Zhao R, Ye Y, Zou Q
Immunity 2024 Mar 12;57(3):528-540.e6
Immunity 2024 Mar 12;57(3):528-540.e6
USP39-Mediated Non-Proteolytic Control of ETS2 Suppresses Nuclear Localization and Activity.
Choi Y, Lee Y, Kim JS, Zhang P, Kim J
Biomolecules 2023 Oct 1;13(10)
Biomolecules 2023 Oct 1;13(10)
Lysine 2-hydroxyisobutyrylation of NAT10 promotes cancer metastasis in an ac4C-dependent manner.
Liao L, He Y, Li SJ, Yu XM, Liu ZC, Liang YY, Yang H, Yang J, Zhang GG, Deng CM, Wei X, Zhu YD, Xu TY, Zheng CC, Cheng C, Li A, Li ZG, Liu JB, Li B
Cell research 2023 May;33(5):355-371
Cell research 2023 May;33(5):355-371
USP39 facilitates breast cancer cell proliferation through stabilization of FOXM1.
Zhang Z, Liu W, Bao X, Sun T, Wang J, Li M, Liu C
American journal of cancer research 2022;12(8):3644-3661
American journal of cancer research 2022;12(8):3644-3661
DNAAF5 promotes hepatocellular carcinoma malignant progression by recruiting USP39 to improve PFKL protein stability.
Liu Y, Wu Q, Sun T, Huang J, Han G, Han H
Frontiers in oncology 2022;12:1032579
Frontiers in oncology 2022;12:1032579
The Deubiquitinase USP39 Promotes Esophageal Squamous Cell Carcinoma Malignancy as a Splicing Factor.
Zhu X, Ma J, Lu M, Liu Z, Sun Y, Chen H
Genes 2022 May 3;13(5)
Genes 2022 May 3;13(5)
Ubiquitin-specific peptidase 39 promotes human glioma cells migration and invasion by facilitating ADAM9 mRNA maturation.
Xiao Y, Ma W, Hu W, Di Q, Zhao X, Ma X, Chen X, Sun P, Wu H, Wu Z, Chen W
Molecular oncology 2022 Jan;16(2):388-404
Molecular oncology 2022 Jan;16(2):388-404
The LINC00623/NAT10 signaling axis promotes pancreatic cancer progression by remodeling ac4C modification of mRNA.
Feng Z, Li K, Qin K, Liang J, Shi M, Ma Y, Zhao S, Liang H, Han D, Shen B, Peng C, Chen H, Jiang L
Journal of hematology & oncology 2022 Aug 17;15(1):112
Journal of hematology & oncology 2022 Aug 17;15(1):112
MiR-1281, a p53-responsive microRNA, impairs the survival of human osteosarcoma cells upon ER stress via targeting USP39.
Jiang J, Ma B, Li X, Jin W, Han C, Wang L, Wang H
American journal of cancer research 2018;8(9):1764-1774
American journal of cancer research 2018;8(9):1764-1774
Identification of a 35S U4/U6.U5 tri-small nuclear ribonucleoprotein (tri-snRNP) complex intermediate in spliceosome assembly.
Chen Z, Gui B, Zhang Y, Xie G, Li W, Liu S, Xu B, Wu C, He L, Yang J, Yi X, Yang X, Sun L, Liang J, Shang Y
The Journal of biological chemistry 2017 Nov 3;292(44):18113-18128
The Journal of biological chemistry 2017 Nov 3;292(44):18113-18128
Knockdown of ubiquitin-specific peptidase 39 inhibited the growth of osteosarcoma cells and induced apoptosis in vitro.
Gan Z, Han K, Lin S, Hu H, Shen Z, Min D
Biological research 2017 Apr 12;50(1):15
Biological research 2017 Apr 12;50(1):15
Knockdown of USP39 by lentivirus-mediated RNA interference suppresses the growth of oral squamous cell carcinoma.
Li KY, Zhang J, Jiang LC, Zhang B, Xia CP, Xu K, Chen HY, Yang QZ, Liu SW, Zhu H
Cancer biomarkers : section A of Disease markers 2016;16(1):137-144
Cancer biomarkers : section A of Disease markers 2016;16(1):137-144
Ubiquitin-specific protease 39 is overexpressed in human lung cancer and promotes tumor cell proliferation in vitro.
Lin Z, Xiong L, Lin Q
Molecular and cellular biochemistry 2016 Nov;422(1-2):97-107
Molecular and cellular biochemistry 2016 Nov;422(1-2):97-107
Lentivirus-mediated inhibition of USP39 suppresses the growth of gastric cancer cells via PARP activation.
Wang X, Yu Q, Huang L, Yu P
Molecular medicine reports 2016 Jul;14(1):301-6
Molecular medicine reports 2016 Jul;14(1):301-6
Overexpression of USP39 predicts poor prognosis and promotes tumorigenesis of prostate cancer via promoting EGFR mRNA maturation and transcription elongation.
Huang Y, Pan XW, Li L, Chen L, Liu X, Lu JL, Zhu XM, Huang H, Yang QW, Ye JQ, Gan SS, Wang LH, Hong Y, Xu DF, Cui XG
Oncotarget 2016 Apr 19;7(16):22016-30
Oncotarget 2016 Apr 19;7(16):22016-30
Reduced USP39 expression inhibits malignant proliferation of medullary thyroid carcinoma in vitro.
An Y, Yang S, Guo K, Ma B, Wang Y
World journal of surgical oncology 2015 Aug 25;13(1):255
World journal of surgical oncology 2015 Aug 25;13(1):255
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- K-562 cells were subjected to SDS PAGE followed by western blot with 23865-1-AP(USP39 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The USP39 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human USP39. This antibody recognizes human antigen. The USP39 antibody has been validated for the following applications: ELISA, WB, IF analysis.
