Tissue expression
Cell line expression
Protein structure
OSGIN1
Oxidative stress induced growth inhibitor 1BDGI, OKL38
This gene encodes an oxidative stress response protein that regulates cell death. Expression of the gene is regulated by p53 and is induced by DNA damage. The protein regulates apoptosis by inducing cytochrome c release from mitochondria. It also appears to be a key regulator of both inflammatory and anti-inflammatory molecules. The loss of this protein correlates with uncontrolled cell growth and tumor formation. Naturally occurring read-through transcription exists between this gene and the neighboring upstream malonyl-CoA decarboxylase (MLYCD) gene, but the read-through transcripts are unlikely to produce a protein product. [provided by RefSeq, Aug 2011]
Top validated antibodies |
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NSJ Bioreagents | RQ7922 | Polyclonal |
WB
EL
ICC
IHC |
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Proteintech Group | 15248-1-AP | 5 references | Polyclonal |
WB
EL |
|
Biorbyt | orb1676247 | Polyclonal |
WB
EL
ICC
IHC |
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antibodies-online | ABIN2492115 | Polyclonal |
WB
IHC |
||
GeneTex | GTX45178 | 1 references | Polyclonal |
WB
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