Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 13710-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13710-1-AP, RRID:AB_2083913
- Product name
- Carboxypeptidase E antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Carboxypeptidase E antibody (Cat. #13710-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CPE correlates with poor prognosis in gastric cancer by promoting tumourigenesis.
Loss of the Golgi-localized v-ATPase subunit does not alter insulin granule formation or pancreatic islet β-cell function.
Agomirs upregulating carboxypeptidase E expression rescue hippocampal neurogenesis and memory deficits in Alzheimer's disease.
Synchronized proinsulin trafficking reveals delayed Golgi export accompanies β-cell secretory dysfunction in rodent models of hyperglycemia.
ER Redox Homeostasis Regulates Proinsulin Trafficking and Insulin Granule Formation in the Pancreatic Islet β-Cell.
Liquid-liquid phase separation facilitates the biogenesis of secretory storage granules.
Development and Validation of a Novel Gene Signature for Predicting the Prognosis by Identifying m5C Modification Subtypes of Cervical Cancer.
Translational Factor eIF4G1 Regulates Glucose Homeostasis and Pancreatic β-Cell Function.
Reductive TCA cycle metabolism fuels glutamine- and glucose-stimulated insulin secretion.
Proteomic analysis of insulin secretory granules in INS-1 cells by protein correlation profiling.
Secretory sorting receptors carboxypeptidase E and secretogranin III in amyloid β-associated neural degeneration in Alzheimer's disease.
Lin J, Huang C, Diao W, Liu H, Lu H, Huang S, Wang J
Heliyon 2024 May 15;10(9):e29901
Heliyon 2024 May 15;10(9):e29901
Loss of the Golgi-localized v-ATPase subunit does not alter insulin granule formation or pancreatic islet β-cell function.
Boyer CK, Blom SE, Machado AE, Rohli KE, Maxson ME, Stephens SB
American journal of physiology. Endocrinology and metabolism 2024 Mar 1;326(3):E245-E257
American journal of physiology. Endocrinology and metabolism 2024 Mar 1;326(3):E245-E257
Agomirs upregulating carboxypeptidase E expression rescue hippocampal neurogenesis and memory deficits in Alzheimer's disease.
Jiang D, Liu H, Li T, Zhao S, Yang K, Yao F, Zhou B, Feng H, Wang S, Shen J, Tang J, Zhang YX, Wang Y, Guo C, Tang TS
Translational neurodegeneration 2024 Apr 26;13(1):24
Translational neurodegeneration 2024 Apr 26;13(1):24
Synchronized proinsulin trafficking reveals delayed Golgi export accompanies β-cell secretory dysfunction in rodent models of hyperglycemia.
Boyer CK, Bauchle CJ, Zhang J, Wang Y, Stephens SB
Scientific reports 2023 Mar 30;13(1):5218
Scientific reports 2023 Mar 30;13(1):5218
ER Redox Homeostasis Regulates Proinsulin Trafficking and Insulin Granule Formation in the Pancreatic Islet β-Cell.
Rohli KE, Boyer CK, Bearrows SC, Moyer MR, Elison WS, Bauchle CJ, Blom SE, Zhang J, Wang Y, Stephens SB
Function (Oxford, England) 2022;3(6):zqac051
Function (Oxford, England) 2022;3(6):zqac051
Liquid-liquid phase separation facilitates the biogenesis of secretory storage granules.
Parchure A, Tian M, Stalder D, Boyer CK, Bearrows SC, Rohli KE, Zhang J, Rivera-Molina F, Ramazanov BR, Mahata SK, Wang Y, Stephens SB, Gershlick DC, von Blume J
The Journal of cell biology 2022 Dec 5;221(12)
The Journal of cell biology 2022 Dec 5;221(12)
Development and Validation of a Novel Gene Signature for Predicting the Prognosis by Identifying m5C Modification Subtypes of Cervical Cancer.
Yu J, Liang LL, Liu J, Liu TT, Li J, Xiu L, Zeng J, Wang TT, Wang D, Liang LJ, Xie DW, Chen DX, An JS, Wu LY
Frontiers in genetics 2021;12:733715
Frontiers in genetics 2021;12:733715
Translational Factor eIF4G1 Regulates Glucose Homeostasis and Pancreatic β-Cell Function.
Jo S, Lockridge A, Mohan R, Esch N, Schlichting R, Panigrahy N, Essawy A, Gustafson E, Alejandro EU
Diabetes 2021 Jan;70(1):155-170
Diabetes 2021 Jan;70(1):155-170
Reductive TCA cycle metabolism fuels glutamine- and glucose-stimulated insulin secretion.
Zhang GF, Jensen MV, Gray SM, El K, Wang Y, Lu D, Becker TC, Campbell JE, Newgard CB
Cell metabolism 2021 Apr 6;33(4):804-817.e5
Cell metabolism 2021 Apr 6;33(4):804-817.e5
Proteomic analysis of insulin secretory granules in INS-1 cells by protein correlation profiling.
Li M, Du W, Zhou M, Zheng L, Song E, Hou J
Biophysics reports 2018;4(6):329-338
Biophysics reports 2018;4(6):329-338
Secretory sorting receptors carboxypeptidase E and secretogranin III in amyloid β-associated neural degeneration in Alzheimer's disease.
Plá V, Paco S, Ghezali G, Ciria V, Pozas E, Ferrer I, Aguado F
Brain pathology (Zurich, Switzerland) 2013 May;23(3):274-84
Brain pathology (Zurich, Switzerland) 2013 May;23(3):274-84
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 13710-1-AP(CPE antibody) at dilution of 1:600
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pituitary using 13710-1-AP(CPE antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Carboxypeptidase E antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Carboxypeptidase E. This antibody recognizes human, mouse, rat antigen. The Carboxypeptidase E antibody has been validated for the following applications: ELISA, WB, IHC analysis.