ABIN1001994

antibody from antibodies-online

Targeting: CASP10 FLICE-2, MCH4

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Antibody Data

Product number

ABIN1001994

Provider

antibodies-online

Product name

anti-Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (C-Term) antibody

Antibody type

Polyclonal

Antigen

Rabbit polyclol caspase-10 antibody was raised against a peptide corresponding to amino acids 505 to 521 of human FLICE21.

Description

Antibody is purified via DEAE-column chromatography.

Reactivity

Human

Host

Rabbit

Epitope

C-Term

Isotype

IgG

Vial size

100 μg

Storage

4°C

Handling

Antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 myl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container?s cap.

References

Submitted references

Fas-associated death domain protein interleukin-1beta-converting enzyme 2 (FLICE2), an ICE/Ced-3 homologue, is proximally involved in CD95- and p55-mediated death signaling.

Vincenz C, Dixit VM
The Journal of biological chemistry 1997 Mar 7;272(10):6578-83

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Caspases: the executioners of apoptosis.

Cohen GM
The Biochemical journal 1997 Aug 15;326 ( Pt 1):1-16

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In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains.

Fernandes-Alnemri T, Armstrong RC, Krebs J, Srinivasula SM, Wang L, Bullrich F, Fritz LC, Trapani JA, Tomaselli KJ, Litwack G, Alnemri ES
Proceedings of the National Academy of Sciences of the United States of America 1996 Jul 23;93(15):7464-9