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Cell line expression
CNOT2
gene productCDC36, NOT2, NOT2H
This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]
- Description
- CCR4-NOT transcription complex subunit 2
- Tissue specificity
- Low tissue specificity
- Subcell location
- Nucleoplasm, Cytosol
- Predicted location
- Intracellular
- Protein family
- Disease related genes
Human disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
- Chromosome
- 12:q15 (70243002 - 70354993)
- Ensembl ID
- ENSG00000111596 (ver. 103.38)
- Orthologs
- Mouse Cnot2: ENSMUSG00000020166
- UniProt
- Q9NZN8
- neXtProt
- NX_Q9NZN8
Human splice variants
Mouse splice variants
| Ensembl | UniProt | RefSeq | Entrez |
|---|---|---|---|
|
ENST00000229195 ENSP00000229195 |
Q9NZN8.174 Q9NZN8 | NP_055330.1 NP_055330 NP_001186232.1 NP_001186232 | CNOT2 4848 |
|
ENST00000418359 ENSP00000412091 |
Q9NZN8.174 Q9NZN8 | NP_001186231.1 NP_001186231 | CNOT2 4848 |
|
ENST00000547780 ENSP00000450283 |
CNOT2 4848 | ||
|
ENST00000547867 ENSP00000448660 |
CNOT2 4848 | ||
|
ENST00000548159 ENSP00000449659 |
CNOT2 4848 | ||
|
ENST00000548338 ENSP00000448808 |
CNOT2 4848 | ||
|
ENST00000549750 ENSP00000449577 |
CNOT2 4848 | ||
|
ENST00000550160 ENSP00000448490 |
CNOT2 4848 | ||
|
ENST00000550194 ENSP00000449446 |
CNOT2 4848 | ||
|
ENST00000550641 ENSP00000448024 |
CNOT2 4848 | ||
|
ENST00000551043 ENSP00000449260 |
Q9NZN8.174 Q9NZN8 | CNOT2 4848 | |
|
ENST00000551132 ENSP00000449801 |
CNOT2 4848 | ||
|
ENST00000551483 ENSP00000448883 |
Q9NZN8.174 Q9NZN8 | CNOT2 4848 | |
|
ENST00000551710 ENSP00000447808 |
CNOT2 4848 | ||
|
ENST00000551873 ENSP00000450090 |
CNOT2 4848 | ||
|
ENST00000552151 ENSP00000483096 |
CNOT2 4848 | ||
|
ENST00000552483 ENSP00000450077 |
CNOT2 4848 | ||
|
ENST00000552599 ENSP00000446507 |
CNOT2 4848 | ||
|
ENST00000552915 ENSP00000447497 |
CNOT2 4848 |
| Ensembl | UniProt | RefSeq | Entrez |
|---|---|---|---|
|
ENSMUST00000020374 ENSMUSP00000020374 |
NP_001032937.1 NP_001032937 | Cnot2 72068 | |
|
ENSMUST00000105265 ENSMUSP00000100900 |
Q8C5L3.142 Q8C5L3 | NP_001346492.1 NP_001346492 NP_001346182.1 NP_001346182 | Cnot2 72068 |
|
ENSMUST00000105267 ENSMUSP00000100902 |
Q8C5L3.142 Q8C5L3 | NP_001032935.2 NP_001032935 NP_001346177.1 NP_001346177 NP_001346180.1 NP_001346180 NP_001346178.1 NP_001346178 NP_001346181.1 NP_001346181 NP_001346179.1 NP_001346179 | Cnot2 72068 |
|
ENSMUST00000164088 ENSMUSP00000127830 |
Cnot2 72068 | ||
|
ENSMUST00000167706 ENSMUSP00000128837 |
Cnot2 72068 | ||
|
ENSMUST00000168036 ENSMUSP00000132315 |
NP_082358.2 NP_082358 | Cnot2 72068 | |
|
ENSMUST00000169507 ENSMUSP00000128720 |
Cnot2 72068 | ||
|
ENSMUST00000169576 ENSMUSP00000130192 |
Cnot2 72068 | ||
|
ENSMUST00000169921 ENSMUSP00000132152 |
Q8C5L3.142 Q8C5L3 | NP_001346176.1 NP_001346176 NP_001032936.2 NP_001032936 | Cnot2 72068 |
|
ENSMUST00000218490 ENSMUSP00000151847 |
Cnot2 72068 | ||
|
ENSMUST00000218744 ENSMUSP00000151501 |
Cnot2 72068 |
* nTPM: Normalized TPM levels represent consensus gene expression calculated using two data sets. Read more
RNA data sourced from Human Protein Atlas.
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