Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Western blot [3]
- Immunocytochemistry [1]
- Immunohistochemistry [4]
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Validation data
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- Product number
- PA5-52722 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- CLPP Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Description
- Immunogen sequence: MGSLLLAAGT PGMRHSLPNS RIMIHQPSGG ARGQATDIAI QAEEIMKLKK QLYNIYAKHT KQSLQVIESA MERDRYMSPM EAQEFGILDK VLVHPPQDGE DEPTLVQKEP VEAAPAAEPV PA Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 92%.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.1 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references CHCHD2 harboring Parkinson's disease-linked T61I mutation precipitates inside mitochondria and induces precipitation of wild-type CHCHD2.
Cornelissen T, Spinazzi M, Martin S, Imberechts D, Vangheluwe P, Bird M, De Strooper B, Vandenberghe W
Human molecular genetics 2020 May 8;29(7):1096-1106
Human molecular genetics 2020 May 8;29(7):1096-1106
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of CLPP in HEK293 cells transfected with control siRNA, target specific siRNA probe #1, using a CLPP Polyclonal Antibody (Product # PA5-52722). Remaining relative intensity is presented. Loading control: Anti-PPIB.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of CLPP in human cell line HEK 293 using a CLPP Polyclonal Antibody (Product # PA5-52722).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of CLPP in mouse cell line NIH-3T3 and rat cell line NBT-II using a CLPP Polyclonal Antibody (Product # PA5-52722).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of CLPP in human cell line U-251 MG shows positivity in mitochondria. Samples were probed using a CLPP Polyclonal Antibody (Product # PA5-52722).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of CLPP in human small intestine using CLPP Polyclonal Antibody (Product # PA5-52722) shows strong granular cytoplasmic positivity in glandular cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of CLPP in human kidney using CLPP Polyclonal Antibody (Product # PA5-52722) shows moderate granular cytoplasmic positivity in cells in tubules.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of CLPP in human liver using CLPP Polyclonal Antibody (Product # PA5-52722) shows moderate granular cytoplasmic positivity in hepatocytes.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of CLPP in human pancreas using CLPP Polyclonal Antibody (Product # PA5-52722) shows moderate granular cytoplasmic positivity in exocrine glandular cells.