BS6491

antibody from Bioworld Technology, Inc
Targeting: CAPNS1 30K, CANP, CANPS, CAPN4, CDPS
Provider product page for BS6491
Western blot
Immunohistochemistry

Antibody data

Product number
BS6491 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CAPNS1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human CAPNS1.
Description
Calpain 1 is an intracellular calcium-dependent protease that cleaves cyto-skeletal and submembranous proteins. Calpains are nonlysosomal, calcium-activated intracellular cysteine proteases. Calpains mediate specific Ca2+-dependent processes including cell fusion, mitosis and meiosis. Calpains are heterodimers of a small regulatory subunit, designated Calpain reg, and one of three large catalytic subunits, designated Calpain 1, Calpain 2 and Calpain p94. Calpastatin regulates Calpain by inhibiting both the proteolytic activity of Calpain and its binding to membranes. Calpastatin exists in two types, tissue type and erythrocyte type, resulting from both alternative splicing and proteolytic processing. Calpain 1 co-localizes with human leukocyte antigen-DR (HLA-DR) on activated microglia in the aging brain. Calpain influences the process of spermatogenesis and the events preceding fertilization, such as the acrosome reaction.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CAPNS1 protein structure - BS6491 shown in red.