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- Antibody Data
- Antigen structure
- References [7]
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- Product number
- ABIN351077 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN351077, RRID:AB_10804062
- Product name
- anti-Neurotrophic Tyrosine Kinase, Receptor, Type 2 (NTRK2) (Extracellular Domain) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide from the extracellular domain of rat, mouse TrkB (BDNF/NT-3 growth factors receptor, TrkB tyrosine kinase, Trk-B) conjugated to an immunogenic carrier protein was used as the immunogen.
- Reactivity
- Human, Mouse, Rat
- Host
- Sheep
- Epitope
- Extracellular Domain
- Isotype
- IgG
- Vial size
- 500 μg
- Storage
- Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability.
- Handling
- Avoid freeze and thaw cycles.
Submitted references Patterns of somatic mutation in human cancer genomes.
Analysis of the human TrkB gene genomic organization reveals novel TrkB isoforms, unusual gene length, and splicing mechanism.
Crystal structures of the neurotrophin-binding domain of TrkA, TrkB and TrkC.
Extracellular domain of neurotrophin receptor trkB: disulfide structure, N-glycosylation sites, and ligand binding.
Human trks: molecular cloning, tissue distribution, and expression of extracellular domain immunoadhesins.
Cloning and chromosomal localization of the human TRK-B tyrosine kinase receptor gene (NTRK2).
Cloning of a non-catalytic form of human trkB and distribution of messenger RNA for trkB in human brain.
Greenman C, Stephens P, Smith R, Dalgliesh GL, Hunter C, Bignell G, Davies H, Teague J, Butler A, Stevens C, Edkins S, O'Meara S, Vastrik I, Schmidt EE, Avis T, Barthorpe S, Bhamra G, Buck G, Choudhury B, Clements J, Cole J, Dicks E, Forbes S, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jenkinson A, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Tofts C, Varian J, Webb T, West S, Widaa S, Yates A, Cahill DP, Louis DN, Goldstraw P, Nicholson AG, Brasseur F, Looijenga L, Weber BL, Chiew YE, DeFazio A, Greaves MF, Green AR, Campbell P, Birney E, Easton DF, Chenevix-Trench G, Tan MH, Khoo SK, Teh BT, Yuen ST, Leung SY, Wooster R, Futreal PA, Stratton MR
Nature 2007 Mar 8;446(7132):153-8
Nature 2007 Mar 8;446(7132):153-8
Analysis of the human TrkB gene genomic organization reveals novel TrkB isoforms, unusual gene length, and splicing mechanism.
Stoilov P, Castren E, Stamm S
Biochemical and biophysical research communications 2002 Jan 25;290(3):1054-65
Biochemical and biophysical research communications 2002 Jan 25;290(3):1054-65
Crystal structures of the neurotrophin-binding domain of TrkA, TrkB and TrkC.
Ultsch MH, Wiesmann C, Simmons LC, Henrich J, Yang M, Reilly D, Bass SH, de Vos AM
Journal of molecular biology 1999 Jul 2;290(1):149-59
Journal of molecular biology 1999 Jul 2;290(1):149-59
Extracellular domain of neurotrophin receptor trkB: disulfide structure, N-glycosylation sites, and ligand binding.
Haniu M, Talvenheimo J, Le J, Katta V, Welcher A, Rohde MF
Archives of biochemistry and biophysics 1995 Sep 10;322(1):256-64
Archives of biochemistry and biophysics 1995 Sep 10;322(1):256-64
Human trks: molecular cloning, tissue distribution, and expression of extracellular domain immunoadhesins.
Shelton DL, Sutherland J, Gripp J, Camerato T, Armanini MP, Phillips HS, Carroll K, Spencer SD, Levinson AD
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995 Jan;15(1 Pt 2):477-91
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995 Jan;15(1 Pt 2):477-91
Cloning and chromosomal localization of the human TRK-B tyrosine kinase receptor gene (NTRK2).
Nakagawara A, Liu XG, Ikegaki N, White PS, Yamashiro DJ, Nycum LM, Biegel JA, Brodeur GM
Genomics 1995 Jan 20;25(2):538-46
Genomics 1995 Jan 20;25(2):538-46
Cloning of a non-catalytic form of human trkB and distribution of messenger RNA for trkB in human brain.
Allen SJ, Dawbarn D, Eckford SD, Wilcock GK, Ashcroft M, Colebrook SM, Feeney R, MacGowan SH
Neuroscience 1994 Jun;60(3):825-34
Neuroscience 1994 Jun;60(3):825-34
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