Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 12296-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12296-1-AP, RRID:AB_2185814
- Product name
- SFXN1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SFXN1 antibody (Cat. #12296-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references SFXN1-mediated immune cell infiltration and tumorigenesis in lung adenocarcinoma: A potential therapeutic target.
Ferritinophagy activation and sideroflexin1-dependent mitochondrial iron overload contribute to patulin-induced cardiac inflammation and fibrosis.
Loss of SFXN1 mitigates lipotoxicity and predicts poor outcome in non-viral hepatocellular carcinoma.
YAP1 alleviates sepsis-induced acute lung injury via inhibiting ferritinophagy-mediated ferroptosis.
The mitochondrial carrier SFXN1 is critical for complex III integrity and cellular metabolism.
Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers.
The liver connexin32 interactome is a novel plasma membrane-mitochondrial signaling nexus.
Li Y, Yang W, Liu C, Zhou S, Liu X, Zhang T, Wu L, Li X, Zhang J, Chang E
International immunopharmacology 2024 May 10;132:111918
International immunopharmacology 2024 May 10;132:111918
Ferritinophagy activation and sideroflexin1-dependent mitochondrial iron overload contribute to patulin-induced cardiac inflammation and fibrosis.
Sun WC, Wang NN, Li R, Sun XC, Liao JW, Yang G, Liu S
The Science of the total environment 2023 Sep 20;892:164472
The Science of the total environment 2023 Sep 20;892:164472
Loss of SFXN1 mitigates lipotoxicity and predicts poor outcome in non-viral hepatocellular carcinoma.
Yagi K, Shimada S, Akiyama Y, Hatano M, Asano D, Ishikawa Y, Ueda H, Watanabe S, Akahoshi K, Ono H, Tanabe M, Tanaka S
Scientific reports 2023 Jun 9;13(1):9449
Scientific reports 2023 Jun 9;13(1):9449
YAP1 alleviates sepsis-induced acute lung injury via inhibiting ferritinophagy-mediated ferroptosis.
Zhang J, Zheng Y, Wang Y, Wang J, Sang A, Song X, Li X
Frontiers in immunology 2022;13:884362
Frontiers in immunology 2022;13:884362
The mitochondrial carrier SFXN1 is critical for complex III integrity and cellular metabolism.
Acoba MG, Alpergin ESS, Renuse S, Fernández-Del-Río L, Lu YW, Khalimonchuk O, Clarke CF, Pandey A, Wolfgang MJ, Claypool SM
Cell reports 2021 Mar 16;34(11):108869
Cell reports 2021 Mar 16;34(11):108869
Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers.
Soula M, Weber RA, Zilka O, Alwaseem H, La K, Yen F, Molina H, Garcia-Bermudez J, Pratt DA, Birsoy K
Nature chemical biology 2020 Dec;16(12):1351-1360
Nature chemical biology 2020 Dec;16(12):1351-1360
The liver connexin32 interactome is a novel plasma membrane-mitochondrial signaling nexus.
Fowler SL, Akins M, Zhou H, Figeys D, Bennett SA
Journal of proteome research 2013 Jun 7;12(6):2597-610
Journal of proteome research 2013 Jun 7;12(6):2597-610
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 12296-1-AP(SFXN1 antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SFXN1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SFXN1. This antibody recognizes human,mouse,rat antigen. The SFXN1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.