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- References [15]
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- Product number
- 14783-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14783-1-AP, RRID:AB_2213357
- Product name
- USP36 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated USP36 antibody (Cat. #14783-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references USP36 stabilizes nucleolar Snail1 to promote ribosome biogenesis and cancer cell survival upon ribotoxic stress.
The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.
USP36 promotes tumorigenesis and drug sensitivity of glioblastoma by deubiquitinating and stabilizing ALKBH5.
The Ubiquitin-specific Protease USP36 Associates with the Microprocessor Complex and Regulates miRNA Biogenesis by SUMOylating DGCR8.
Imbalance in ALR ubiquitination accelerates the progression of nonalcoholic steatohepatitis to hepatocellular carcinoma.
Prostate-specific oncogene OTUD6A promotes prostatic tumorigenesis via deubiquitinating and stabilizing c-Myc.
Intracellular energy controls dynamics of stress-induced ribonucleoprotein granules.
USP36 facilitates esophageal squamous carcinoma progression via stabilizing YAP.
USP36-Mediated Deubiquitination of DOCK4 Contributes to the Diabetic Renal Tubular Epithelial Cell Injury via Wnt/β-Catenin Signaling Pathway.
Anakinra Activates Superoxide Dismutase 2 to Mitigate Inflammasome Activity.
The deubiquitinase USP36 Regulates DNA replication stress and confers therapeutic resistance through PrimPol stabilization.
USP36 protects proximal tubule cells from ischemic injury by stabilizing c-Myc and SOD2.
PME-1 is regulated by USP36 in ERK and Akt signaling pathways.
Loss of the deubiquitinase USP36 destabilizes the RNA helicase DHX33 and causes preimplantation lethality in mice.
Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis.
Qin K, Yu S, Liu Y, Guo R, Guo S, Fei J, Wang Y, Jia K, Xu Z, Chen H, Li F, Niu M, Dai MS, Dai L, Cao Y, Zhang Y, Xiao ZJ, Yi Y
Nature communications 2023 Oct 13;14(1):6473
Nature communications 2023 Oct 13;14(1):6473
The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing.
Chen Y, Li Y, Dai RS, Savage JC, Shinde U, Klimek J, David LL, Young EA, Hafner M, Sears RC, Sun XX, Dai MS
Nucleic acids research 2023 May 8;51(8):3934-3949
Nucleic acids research 2023 May 8;51(8):3934-3949
USP36 promotes tumorigenesis and drug sensitivity of glioblastoma by deubiquitinating and stabilizing ALKBH5.
Chang G, Xie GS, Ma L, Li P, Li L, Richard HT
Neuro-oncology 2023 May 4;25(5):841-853
Neuro-oncology 2023 May 4;25(5):841-853
The Ubiquitin-specific Protease USP36 Associates with the Microprocessor Complex and Regulates miRNA Biogenesis by SUMOylating DGCR8.
Li Y, Carey TS, Feng CH, Zhu HM, Sun XX, Dai MS
Cancer research communications 2023 Mar;3(3):459-470
Cancer research communications 2023 Mar;3(3):459-470
Imbalance in ALR ubiquitination accelerates the progression of nonalcoholic steatohepatitis to hepatocellular carcinoma.
Zheng M, Ai Z, Guo Y, Chen Y, Xie P, An W
Oncogene 2023 Jan;42(4):308-321
Oncogene 2023 Jan;42(4):308-321
Prostate-specific oncogene OTUD6A promotes prostatic tumorigenesis via deubiquitinating and stabilizing c-Myc.
Peng Y, Liu J, Wang Z, Cui C, Zhang T, Zhang S, Gao P, Hou Z, Liu H, Guo J, Zhang J, Wen Y, Wei W, Zhang L, Liu J, Long J
Cell death and differentiation 2022 Sep;29(9):1730-1743
Cell death and differentiation 2022 Sep;29(9):1730-1743
Intracellular energy controls dynamics of stress-induced ribonucleoprotein granules.
Wang T, Tian X, Kim HB, Jang Y, Huang Z, Na CH, Wang J
Nature communications 2022 Sep 23;13(1):5584
Nature communications 2022 Sep 23;13(1):5584
USP36 facilitates esophageal squamous carcinoma progression via stabilizing YAP.
Zhang W, Luo J, Xiao Z, Zang Y, Li X, Zhou Y, Zhou J, Tian Z, Zhu J, Zhao X
Cell death & disease 2022 Dec 5;13(12):1021
Cell death & disease 2022 Dec 5;13(12):1021
USP36-Mediated Deubiquitination of DOCK4 Contributes to the Diabetic Renal Tubular Epithelial Cell Injury via Wnt/β-Catenin Signaling Pathway.
Zhu S, Hou S, Lu Y, Sheng W, Cui Z, Dong T, Feng H, Wan Q
Frontiers in cell and developmental biology 2021;9:638477
Frontiers in cell and developmental biology 2021;9:638477
Anakinra Activates Superoxide Dismutase 2 to Mitigate Inflammasome Activity.
Pariano M, Pieroni S, De Luca A, Iannitti RG, Borghi M, Puccetti M, Giovagnoli S, Renga G, D'Onofrio F, Bellet MM, Stincardini C, Della-Fazia MA, Servillo G, van de Veerdonk FL, Costantini C, Romani L
International journal of molecular sciences 2021 Jun 18;22(12)
International journal of molecular sciences 2021 Jun 18;22(12)
The deubiquitinase USP36 Regulates DNA replication stress and confers therapeutic resistance through PrimPol stabilization.
Yan Y, Xu Z, Huang J, Guo G, Gao M, Kim W, Zeng X, Kloeber JA, Zhu Q, Zhao F, Luo K, Lou Z
Nucleic acids research 2020 Dec 16;48(22):12711-12726
Nucleic acids research 2020 Dec 16;48(22):12711-12726
USP36 protects proximal tubule cells from ischemic injury by stabilizing c-Myc and SOD2.
Liu Q, Sheng W, Ma Y, Zhen J, Roy S, Alvira Jafar C, Xin W, Wan Q
Biochemical and biophysical research communications 2019 May 28;513(2):502-508
Biochemical and biophysical research communications 2019 May 28;513(2):502-508
PME-1 is regulated by USP36 in ERK and Akt signaling pathways.
Kim SY, Choi J, Lee DH, Park JH, Hwang YJ, Baek KH
FEBS letters 2018 May;592(9):1575-1588
FEBS letters 2018 May;592(9):1575-1588
Loss of the deubiquitinase USP36 destabilizes the RNA helicase DHX33 and causes preimplantation lethality in mice.
Fraile JM, Campos-Iglesias D, Rodríguez F, Astudillo A, Vilarrasa-Blasi R, Verdaguer-Dot N, Prado MA, Paulo JA, Gygi SP, Martín-Subero JI, Freije JMP, López-Otín C
The Journal of biological chemistry 2018 Feb 9;293(6):2183-2194
The Journal of biological chemistry 2018 Feb 9;293(6):2183-2194
Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis.
Romani L, Oikonomou V, Moretti S, Iannitti RG, D'Adamo MC, Villella VR, Pariano M, Sforna L, Borghi M, Bellet MM, Fallarino F, Pallotta MT, Servillo G, Ferrari E, Puccetti P, Kroemer G, Pessia M, Maiuri L, Goldstein AL, Garaci E
Nature medicine 2017 May;23(5):590-600
Nature medicine 2017 May;23(5):590-600
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The USP36 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human USP36. This antibody recognizes human, mouse antigen. The USP36 antibody has been validated for the following applications: ELISA, WB analysis.
