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- References [14]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 25349-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- SENP1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SENP1 antibody (Cat. #25349-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Sentrin-specific protease 1 maintains mitochondrial homeostasis through targeting the deSUMOylation of sirtuin-3 to alleviate oxidative damage induced by hepatic ischemia/reperfusion.
Nicotinamide mononucleotide attenuates airway epithelial barrier dysfunction via inhibiting SIRT3 SUMOylation in asthma.
SENP1 inhibits ferroptosis and promotes head and neck squamous cell carcinoma by regulating ACSL4 protein stability via SUMO1.
Astragaloside IV combined with ligustrazine ameliorates abnormal mitochondrial dynamics via Drp1 SUMO/deSUMOylation in cerebral ischemia-reperfusion injury.
miR‑122/SENP1 axis confers stemness and chemoresistance to liver cancer through Wnt/β‑catenin signaling.
LncRNA FRMD6-AS1 promotes hepatocellular carcinoma cell migration and stemness by regulating SENP1/HIF-1α axis.
Mitochondrial SENP2 regulates the assembly of SDH complex under metabolic stress.
Lactate regulates cell cycle by remodelling the anaphase promoting complex.
Multiple-Site SUMOylation of FMDV 3C Protease and Its Negative Role in Viral Replication.
Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway.
SCARF1 promotes M2 polarization of Kupffer cells via calcium-dependent PI3K-AKT-STAT3 signalling to improve liver transplantation.
Long noncoding RNA MCM3AP-AS1 enhances cell proliferation and metastasis in colorectal cancer by regulating miR-193a-5p/SENP1.
A fine-tuning mechanism underlying self-control for autophagy: deSUMOylation of BECN1 by SENP3.
SENP1 Interacts with HIF1α to Regulate Glycolysis of Prostatic Carcinoma Cells.
Xia K, Guo J, Yu B, Wang T, Qiu Q, Chen Q, Qiu T, Zhou J, Zheng S
Free radical biology & medicine 2024 Jan;210:378-389
Free radical biology & medicine 2024 Jan;210:378-389
Nicotinamide mononucleotide attenuates airway epithelial barrier dysfunction via inhibiting SIRT3 SUMOylation in asthma.
Liang J, Zhou C, Zhang C, Liang S, Zhou Z, Zhou Z, Wu C, Zhao H, Meng X, Zou F, Yu C, Cai S
International immunopharmacology 2024 Jan 25;127:111328
International immunopharmacology 2024 Jan 25;127:111328
SENP1 inhibits ferroptosis and promotes head and neck squamous cell carcinoma by regulating ACSL4 protein stability via SUMO1.
Xu X, Mao Y, Feng Z, Dai F, Gu T, Zheng J
Oncology reports 2024 Feb;51(2)
Oncology reports 2024 Feb;51(2)
Astragaloside IV combined with ligustrazine ameliorates abnormal mitochondrial dynamics via Drp1 SUMO/deSUMOylation in cerebral ischemia-reperfusion injury.
Chen X, Yang T, Zhou Y, Mei Z, Zhang W
CNS neuroscience & therapeutics 2024 Apr;30(4):e14725
CNS neuroscience & therapeutics 2024 Apr;30(4):e14725
miR‑122/SENP1 axis confers stemness and chemoresistance to liver cancer through Wnt/β‑catenin signaling.
Dai J, Hao Y, Chen X, Yu Q, Wang B
Oncology letters 2023 Sep;26(3):390
Oncology letters 2023 Sep;26(3):390
LncRNA FRMD6-AS1 promotes hepatocellular carcinoma cell migration and stemness by regulating SENP1/HIF-1α axis.
Sun W, Lei X, Lu Q, Wu Q, Ma Q, Huang D, Zhang Y
Pathology, research and practice 2023 Mar;243:154377
Pathology, research and practice 2023 Mar;243:154377
Mitochondrial SENP2 regulates the assembly of SDH complex under metabolic stress.
Liu Y, Liu K, Thorne RF, Shi R, Zhang Q, Wu M, Liu L
Cell reports 2023 Feb 28;42(2):112041
Cell reports 2023 Feb 28;42(2):112041
Lactate regulates cell cycle by remodelling the anaphase promoting complex.
Liu W, Wang Y, Bozi LHM, Fischer PD, Jedrychowski MP, Xiao H, Wu T, Darabedian N, He X, Mills EL, Burger N, Shin S, Reddy A, Sprenger HG, Tran N, Winther S, Hinshaw SM, Shen J, Seo HS, Song K, Xu AZ, Sebastian L, Zhao JJ, Dhe-Paganon S, Che J, Gygi SP, Arthanari H, Chouchani ET
Nature 2023 Apr;616(7958):790-797
Nature 2023 Apr;616(7958):790-797
Multiple-Site SUMOylation of FMDV 3C Protease and Its Negative Role in Viral Replication.
Wu X, Hu Y, Sui C, Pan L, Yoo D, Miller LC, Lee C, Cong X, Li J, Du Y, Qi J
Journal of virology 2022 Sep 14;96(17):e0061222
Journal of virology 2022 Sep 14;96(17):e0061222
Momordin Ic induces G0/1 phase arrest and apoptosis in colon cancer cells by suppressing SENP1/c-MYC signaling pathway.
Xianjun F, Xirui X, Jie T, Huiwen M, Shaojun Z, Qiaoyun L, Yunxin L, Xuqun S
Journal of pharmacological sciences 2021 Aug;146(4):249-258
Journal of pharmacological sciences 2021 Aug;146(4):249-258
SCARF1 promotes M2 polarization of Kupffer cells via calcium-dependent PI3K-AKT-STAT3 signalling to improve liver transplantation.
Xu XS, Feng ZH, Cao D, Wu H, Wang MH, Li JZ, Gong JP
Cell proliferation 2021 Apr;54(4):e13022
Cell proliferation 2021 Apr;54(4):e13022
Long noncoding RNA MCM3AP-AS1 enhances cell proliferation and metastasis in colorectal cancer by regulating miR-193a-5p/SENP1.
Zhou M, Bian Z, Liu B, Zhang Y, Cao Y, Cui K, Sun S, Li J, Zhang J, Wang X, Li C, Yao S, Yin Y, Fei B, Huang Z
Cancer medicine 2021 Apr;10(7):2470-2481
Cancer medicine 2021 Apr;10(7):2470-2481
A fine-tuning mechanism underlying self-control for autophagy: deSUMOylation of BECN1 by SENP3.
Liu K, Guo C, Lao Y, Yang J, Chen F, Zhao Y, Yang Y, Yang J, Yi J
Autophagy 2020 Jun;16(6):975-990
Autophagy 2020 Jun;16(6):975-990
SENP1 Interacts with HIF1α to Regulate Glycolysis of Prostatic Carcinoma Cells.
Wang C, Tao W, Ni S, Chen Q
International journal of biological sciences 2019;15(2):395-403
International journal of biological sciences 2019;15(2):395-403
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 25349-1-AP( SENP1 Antibody) at dilution of 1:1000
- Other comments
- WB
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemistry of paraffin-embedded human liver tissue slide using 25349-1-AP( SENP1 Antibody) at dilution of 1:50 (under 40x lens)
- Other comments
- IHC
