13082-1-AP

antibody from Proteintech Group

Targeting: IL17A CTLA8, IL-17, IL-17A, IL17

Provider product page for 13082-1-AP

Western blot

ELISA

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [72]
Comments [0]
Validations
Western blot [1]
Immunoprecipitation [1]
Immunohistochemistry [1]

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Product number: 13082-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#13082-1-AP, RRID:AB_10644322
Product name: IL-17 antibody
Antibody type: Polyclonal
Description: IL-17 antibody (Cat. #13082-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, ELISA.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

IL17A protein structure - 13082-1-AP shown in red.

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PARP1 promoter hypermethylation promotes arsenic-induced skin damage by driving telomere dysfunction-mediated keratinocyte senescence.

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Astilbin Alleviates IL-17-Induced Hyperproliferation and Inflammation in HaCaT Cells via Inhibiting Ferroptosis Through the cGAS-STING Pathway.

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IL-17 enhanced the susceptibility to fluoxetine resistance in depression via the JAK1-STAT6 signaling pathway.

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Drug-loaded microneedle patches containing regulatory T cell-derived exosomes for psoriasis treatment.

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Rubia cordifolia L. extract ameliorates vitiligo by inhibiting the CXCL10/CXCL9/STAT1 signaling pathway.

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Schisandrol B inhibits calcification of aortic valve by targeting p53 related inflammatory and senescence.

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Luo M, Yang X, Zhou M, Zhang J, Yu B, Lian H, Ye J
iScience 2024 Oct 18;27(10):111028

Successful treatment with guselkumab of anti-p200 pemphigoid associated with plaque psoriasis.

Kitayama S, Makino T, Kataoka K, Mori S, Takemoto K, Furukawa F, Torai R, Hayashi M, Mizawa M, Ishii N, Hashimoto T, Shimizu T
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Identification of a novel oligopeptide from defatted walnut meal hydrolysate as a potential neuroprotective agent.

Gao F, Zhang Z, Xue N, Ma Y, Jiao J, Wang C, Zhang K, Lin Y, Li S, Guo Z, An J, Wang P, Xu B, Lei H
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Yao C, Lu L, Lan D, Zhu X, Li X, Gao Y, Zhou Y, Wang Y, Xu Y, Qi S
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SLAMF3 promotes Th17 differentiation and is reversed by iguratimod through JAK1/STAT3 pathway in primary Sjögren's syndrome.

Hu P, Cai J, Yang C, Xu L, Ma S, Song H, Yang P
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L.acidophilus participates in intestinal inflammation induced by PM(2.5) through affecting the Treg/Th17 balance.

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NPSR1 promotes chronic colitis through regulating CD4(+) T cell effector function in inflammatory bowel disease.

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Liver metastasis affects progression pattern during immune checkpoint inhibitors monotherapy in gastric cancer.

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PCSK9 inhibition ameliorates experimental autoimmune myocarditis by reducing Th17 cell differentiation through LDLR/STAT-3/ROR-γt pathway.

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Rat tight junction proteins are disrupted after subchronic exposure to okadaic acid.

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SMURF1 inhibits the Th17 and Th17.1 polarization and improves the Treg/Th17 imbalance in systemic lupus erythematosus through the ubiquitination of RORγt.

Zhong W, Feng L, Tian W, Qu H, Xu H, Ning K, Liu L, Liu W, Gong X, Chen H
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Heparanase Contributes to Psoriatic Lesions Through Crosstalk with IL-17 Pathway.

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Porphyromonas gingivalis is a risk factor for the development of nonalcoholic fatty liver disease via ferroptosis.

Yao C, Lan D, Li X, Wang Y, Qi S, Liu Y
Microbes and infection 2023 Jan-Feb;25(1-2):105040

Loganin reduces neuroinflammation and promotes functional recovery after spinal cord injury through inhibiting NF-κB/NLRP3 signalling.

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Coprophagy Prevention Affects the Reproductive Performance in New Zealand White Rabbits Is Mediated through Nox4-ROS-NFκB Pathway.

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Identification of a novel immune gene panel in tongue squamous cell carcinoma.

Sun J, Guo F, Tang Q, Chen G, Peng J, Shen Y, Zhang J, Hu J, Yang C
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Gut Microbiota Protected Against pseudomonas aeruginosa Pneumonia via Restoring Treg/Th17 Balance and Metabolism.

Wen L, Shi L, Kong XL, Li KY, Li H, Jiang DX, Zhang F, Zhou ZG
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SGLT2 inhibitor, canagliflozin, ameliorates cardiac inflammation in experimental autoimmune myocarditis.

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International immunopharmacology 2022 Sep;110:109024

The role of proteoglycan form of DMP1 in cranial repair.

Liu Y, Niu P, Zhou M, Xue H
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Human breast milk-derived exosomes through inhibiting AT II cell apoptosis to prevent bronchopulmonary dysplasia in rat lung.

Zhou Y, Liu Y, Xu G, Liu L, Li H, Li Y, Yin J, Wang X, Yu Z
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SPRC Suppresses Experimental Periodontitis by Modulating Th17/Treg Imbalance.

Peng Q, Zhao B, Lin J, Liu H, Zhou R, Lan D, Yao C, Cong S, Tao S, Zhu Y, Wang R, Qi S
Frontiers in bioengineering and biotechnology 2021;9:737334

Autoimmune Hepatitis with Elevated Serum IgG4 Levels Have a High Prevalence of Cirrhosis at Diagnosis.

Xue M, Shen Y, Fan X, Shen M, Yang L
Canadian journal of gastroenterology & hepatology 2021;2021:6692511

IL-17 is expressed on beta and alpha cells of donors with type 1 and type 2 diabetes.

Rajendran S, Quesada-Masachs E, Zilberman S, Graef M, Kiosses WB, Chu T, Benkahla MA, Lee JM, von Herrath M
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Maiwei Yangfei decoction prevents bleomycin-induced pulmonary fibrosis in mice.

Xu Y, Peng W, Han D, Feng F, Wang Z, Gu C, Zhou X, Wu Q
Experimental and therapeutic medicine 2021 Nov;22(5):1306

Effects of Qing Chang Suppository Powder and its Ingredients on IL-17 Signal Pathway in HT-29 Cells and DSS-induced Mice.

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Phytomedicine : international journal of phytotherapy and phytopharmacology 2021 Jul;87:153573

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Shimizu Y, Suzuki S, Ukai M, Hattori S, Yoshikawa N, Kajiyama H
Anticancer research 2021 Jan;41(1):249-258

The role of IP-10 and its receptor CXCR3 in early pregnancy.

Jiang Y, Huang F, Chai X, Yuan W, Ding H, Wu X
Molecular immunology 2021 Dec;140:59-69

Interleukin-17 is a potential player and treatment target in severe chronic spontaneous urticaria.

Sabag DA, Matanes L, Bejar J, Sheffer H, Barzilai A, Church MK, Toubi E, Maurer M, Vadasz Z
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2020 Jul;50(7):799-804

IL-17A increases MHC class I expression and promotes T cell activation in papillary thyroid cancer patients with coexistent Hashimoto's thyroiditis.

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Histone Acetyltransferase Mof Affects the Progression of DSS-Induced Colitis.

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IL-17 Promotes Scar Formation by Inducing Macrophage Infiltration.

Zhang J, Qiao Q, Liu M, He T, Shi J, Bai X, Zhang Y, Li Y, Cai W, Han S, Guan H, Hu D
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MBD2 Regulates Th17 Cell Differentiation and Experimental Severe Asthma by Affecting IRF4 Expression.

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Experimental and therapeutic medicine 2017 Sep;14(3):2126-2134

Interleukin-17A Plays the Same Role on Mice Acute Lung Injury Respectively Induced by Lipopolysaccharide and Paraquat.

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Wu YH, Liu W, Xue B, Zhang L, Liu XY, Liu B, Wang Y, Cai Y, Duan R
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Activated human valvular interstitial cells sustain interleukin-17 production to recruit neutrophils in infective endocarditis.

Yeh CY, Shun CT, Kuo YM, Jung CJ, Hsieh SC, Chiu YL, Chen JW, Hsu RB, Yang CJ, Chia JS
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Interleukin-17 retinotoxicity is prevented by gene transfer of a soluble interleukin-17 receptor acting as a cytokine blocker: implications for age-related macular degeneration.

Ardeljan D, Wang Y, Park S, Shen D, Chu XK, Yu CR, Abu-Asab M, Tuo J, Eberhart CG, Olsen TW, Mullins RF, White G, Wadsworth S, Scaria A, Chan CC
PloS one 2014;9(4):e95900

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Li Q, Li Q, Chen J, Liu Y, Zhao X, Tan B, Ai J, Zhang Z, Song J, Shan B
Oncology reports 2013 Sep;30(3):1215-22

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Rodero MP, Hodgson SS, Hollier B, Combadiere C, Khosrotehrani K
The Journal of investigative dermatology 2013 Mar;133(3):783-792

Implications of Th1 and Th17 cells in pathogenesis of oral lichen planus.

Xie S, Ding L, Xiong Z, Zhu S
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2012 Jun;32(3):451-457

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: U-937 cells were subjected to SDS PAGE followed by western blot with 13082-1-AP(IL17A antibody) at dilution of 1:500
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: IP Result of anti-IL17A (IP:13082-1-AP, 3ug; Detection:13082-1-AP 1:300) with U-937 cells lysate 6500ug.
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The IL-17 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human IL-17. This antibody recognizes human, mouse antigen. The IL-17 antibody has been validated for the following applications: ELISA, IHC, IP, WB analysis.
Appendix: 13082-1-AP.pdf

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