PSMD8

gene product
HIP6, HYPF, Nin1p, p31, Rpn12, S14
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1. [provided by RefSeq, Jul 2008]
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148 antibodies from 22 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Atlas Antibodies
1 antibody
Biorbyt
11 antibodies
Novus Biologicals
4 antibodies
antibodies-online
61 antibodies
LifeSpan BioSciences, Inc.
13 antibodies
Invitrogen Antibodies
3 antibodies
GeneTex
3 antibodies
Bioworld Technology, Inc
1 antibody
St John's Laboratory
1 antibody
Enzo Life Sciences
7 antibodies
Abnova Corporation
4 antibodies
OriGene
3 antibodies
Creative Biolabs
10 antibodies
Aviva Systems Biology
1 antibody
ProSci
2 antibodies
Sigma-Aldrich
3 antibodies
United States Biological
3 antibodies
MyBioSource
2 antibodies
Abgent
1 antibody
Creative Diagnostics
1 antibody
EMD Millipore
1 antibody