Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 11746-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11746-1-AP, RRID:AB_2247970
- Product name
- HBP1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated HBP1 antibody (Cat. #11746-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Overexpression of macrophage migration inhibitory factor protects against pressure overload-induced cardiac hypertrophy through regulating the miR-29b-3p/HBP1 axis.
The transcription factor HBP1 promotes ferroptosis in tumor cells by regulating the UHRF1-CDO1 axis.
Targeting of HBP1/TIMP3 axis as a novel strategy against breast cancer.
HBP1 inhibits the development of type 2 diabetes mellitus through transcriptional activation of the IGFBP1 gene.
CRISPR interference and activation of the microRNA-3662-HBP1 axis control progression of triple-negative breast cancer.
The human GID complex engages two independent modules for substrate recruitment.
miR-29c&b2 encourage extramedullary infiltration resulting in the poor prognosis of acute myeloid leukemia.
HBP1-mediated transcriptional repression of AFP inhibits hepatoma progression.
MDM2 promotes genome instability by ubiquitinating the transcription factor HBP1.
Transcription factor HMG box-containing protein 1 (HBP1) modulates mitotic clonal expansion (MCE) during adipocyte differentiation.
A positive feedback loop between Pim-1 kinase and HBP1 transcription factor contributes to hydrogen peroxide-induced premature senescence and apoptosis.
HBP1-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/EZH2 Pathways and Its Impact on Cell Senescence and Tumorigenesis.
MYC through miR-17-92 suppresses specific target genes to maintain survival, autonomous proliferation, and a neoplastic state.
HBP1-mediated transcriptional regulation of DNA methyltransferase 1 and its impact on cell senescence.
Wen L, Chen W, Zhu C, Li J, Zhou J, Zhang M, Zhang W, Xue Q
Physiological reports 2024 Jun;12(12):e16022
Physiological reports 2024 Jun;12(12):e16022
The transcription factor HBP1 promotes ferroptosis in tumor cells by regulating the UHRF1-CDO1 axis.
Yang R, Zhou Y, Zhang T, Wang S, Wang J, Cheng Y, Li H, Jiang W, Yang Z, Zhang X
PLoS biology 2023 Jul;21(7):e3001862
PLoS biology 2023 Jul;21(7):e3001862
Targeting of HBP1/TIMP3 axis as a novel strategy against breast cancer.
Zhou Y, Zhang T, Wang S, Yang R, Jiao Z, Lu K, Li H, Jiang W, Zhang X
Pharmacological research 2023 Aug;194:106846
Pharmacological research 2023 Aug;194:106846
HBP1 inhibits the development of type 2 diabetes mellitus through transcriptional activation of the IGFBP1 gene.
Cheng Y, Yang R, Zhou Y, Wang J, Zhang T, Wang S, Li H, Jiang W, Zhang X
Aging 2022 Nov 2;14(21):8763-8782
Aging 2022 Nov 2;14(21):8763-8782
CRISPR interference and activation of the microRNA-3662-HBP1 axis control progression of triple-negative breast cancer.
Yi B, Wang S, Wang X, Liu Z, Zhang C, Li M, Gao S, Wei S, Bae S, Stringer-Reasor E, Wang L, Liu R
Oncogene 2022 Jan;41(2):268-279
Oncogene 2022 Jan;41(2):268-279
The human GID complex engages two independent modules for substrate recruitment.
Mohamed WI, Park SL, Rabl J, Leitner A, Boehringer D, Peter M
EMBO reports 2021 Nov 4;22(11):e52981
EMBO reports 2021 Nov 4;22(11):e52981
miR-29c&b2 encourage extramedullary infiltration resulting in the poor prognosis of acute myeloid leukemia.
Wei Y, Lu W, Yu Y, Zhai Y, Guo H, Yang S, Zhao C, Zhang Y, Liu J, Liu Y, Fei J, Shi J
Oncogene 2021 May;40(19):3434-3448
Oncogene 2021 May;40(19):3434-3448
HBP1-mediated transcriptional repression of AFP inhibits hepatoma progression.
Cao Z, Cheng Y, Wang J, Liu Y, Yang R, Jiang W, Li H, Zhang X
Journal of experimental & clinical cancer research : CR 2021 Apr 1;40(1):118
Journal of experimental & clinical cancer research : CR 2021 Apr 1;40(1):118
MDM2 promotes genome instability by ubiquitinating the transcription factor HBP1.
Cao Z, Xue J, Cheng Y, Wang J, Liu Y, Li H, Jiang W, Li G, Gui Y, Zhang X
Oncogene 2019 Jun;38(24):4835-4855
Oncogene 2019 Jun;38(24):4835-4855
Transcription factor HMG box-containing protein 1 (HBP1) modulates mitotic clonal expansion (MCE) during adipocyte differentiation.
Chan CY, Yu P, Chang FT, Chen ZH, Lee MF, Huang CY
Journal of cellular physiology 2018 May;233(5):4205-4215
Journal of cellular physiology 2018 May;233(5):4205-4215
A positive feedback loop between Pim-1 kinase and HBP1 transcription factor contributes to hydrogen peroxide-induced premature senescence and apoptosis.
Wang S, Cao Z, Xue J, Li H, Jiang W, Cheng Y, Li G, Zhang X
The Journal of biological chemistry 2017 May 19;292(20):8207-8222
The Journal of biological chemistry 2017 May 19;292(20):8207-8222
HBP1-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/EZH2 Pathways and Its Impact on Cell Senescence and Tumorigenesis.
Chen Y, Pan K, Wang P, Cao Z, Wang W, Wang S, Hu N, Xue J, Li H, Jiang W, Li G, Zhang X
The Journal of biological chemistry 2016 Jun 10;291(24):12688-12705
The Journal of biological chemistry 2016 Jun 10;291(24):12688-12705
MYC through miR-17-92 suppresses specific target genes to maintain survival, autonomous proliferation, and a neoplastic state.
Li Y, Choi PS, Casey SC, Dill DL, Felsher DW
Cancer cell 2014 Aug 11;26(2):262-72
Cancer cell 2014 Aug 11;26(2):262-72
HBP1-mediated transcriptional regulation of DNA methyltransferase 1 and its impact on cell senescence.
Pan K, Chen Y, Roth M, Wang W, Wang S, Yee AS, Zhang X
Molecular and cellular biology 2013 Mar;33(5):887-903
Molecular and cellular biology 2013 Mar;33(5):887-903
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The HBP1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human HBP1. This antibody recognizes human antigen. The HBP1 antibody has been validated for the following applications: ELISA, WB analysis.