Antibody data
- Antibody Data
- Antigen structure
- References [1]
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- Validations
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- Product number
- PA5-50485 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- SLC7A5 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- The antibody detects endogenous levels of total CD98 / SLC3A2 protein.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.4 mg/mL
- Storage
- -20°C
Submitted references A novel therapeutic approach for anaplastic thyroid cancer through inhibition of LAT1.
Enomoto K, Sato F, Tamagawa S, Gunduz M, Onoda N, Uchino S, Muragaki Y, Hotomi M
Scientific reports 2019 Oct 10;9(1):14616
Scientific reports 2019 Oct 10;9(1):14616
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Supportive validation
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- Invitrogen Antibodies (provider)
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- Experimental details
- Figure 2 Detection of LAT1 and 4F2hc by western blotting and immunofluorescence analyses in 8505C, OCUT-2, and OCUT-6 human ATC cells. ( A ) Expression of LAT1 and 4F2hc levels in the indicated cells detected by western blotting. ( B ) The densitometry value of LAT1 was normalized alpha-tubulin. ( C ) The densitometry value of 4F2hc was normalized alpha-tubulin. ( D ) DAPI (4,6-diamidino-2-phenylindole is a blue fluorescent stain specific for DNA) nuclear staining was shown in blue. Both LAT1 (green) and 4F2hc immunoreactivities (red) were detected on the plasma membrane of 8505C, OCUT-2, or OCUT-6 cells. LAT1 (green) and 4F2hc immunostaining (red), and DAPI (blue) were merged and shown in 2D, indicating the coexistence of LAT1 with 4F2hc in the plasma membrane of 8505C, OCUT-2, or OCUT-6 cells, respectively.