28670-1-AP

antibody from Proteintech Group

Targeting: SLC7A5 CD98, D16S469E, E16, LAT1, MPE16

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

28670-1-AP

Provider

Proteintech Group

Product name

SLC7A5 antibody

Antibody type

Polyclonal

Description

KD/KO validated SLC7A5 antibody (Cat. #28670-1-AP) is a rabbit polyclonal antibody that shows reactivity with Human and has been validated for the following applications: IHC, WB, ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

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Nature communications 2026 Mar 6;17(1)

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SLC7A5-ERBB2 axis drives olaparib resistance via de novo lipid synthesis in ovarian cancer.

Liu S, He Y, Ning X, Xu W, Hu X, Qin L, Yang Y, Chen X, Ma R
Oncogene 2026 Jan;45(2):140-263

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HHLA2 promotes immune evasion in EGFR-mutant lung cancer by inhibiting CD8(+) T cell glutamine metabolism via KIR3DL3 interaction.

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Cancer letters 2026 Feb 28;639:218219

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The lncRNA DAMER selectively guides m(6)A-dependent regulation of ATF4 and asparagine metabolism under nutrient stress in cancer.

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Identification of differentially expressed genes associated with ferroptosis in ulcerative colitis.

Zhang F, Jiang X, Chen X, Wang Z, Xia J, Wang B, Wang M, Ding Y
PloS one 2025;20(7):e0327990

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KRAS mutation promotes immune escape of lung adenocarcinoma via ZNF24/SLC7A5/PD-L1 axis.

Li L, Feng Q, Jiang Y, Yang L, Fang H, Xu W, Wang Y, Pan X, Yang J
BMC cancer 2025 Sep 2;25(1):1417

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Micropeptide hSPAR regulates glutamine levels and suppresses mammary tumor growth via a TRIM21-P27KIP1-mTOR axis.

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The EMBO journal 2025 Mar;44(5):1414-1441

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SLC7A5 regulates tryptophan uptake and PD‑L1 expression levels via the kynurenine pathway in ovarian cancer.

Jiang R, Jin B, Sun Y, Chen Z, Wan D, Feng J, Ying L, Peng C, Gu L
Oncology letters 2025 Jan;29(1):26

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Microenvironmental β-TrCP negates amino acid transport to trigger CD8(+) T cell exhaustion in human non-small cell lung cancer.

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DRAM1 enhances the proliferation and metastasis of gastric cancer through the PI3K/AKT/mTOR signaling pathway and energy metabolism.

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Scientific reports 2025 Jan 28;15(1):3542

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European journal of nuclear medicine and molecular imaging 2025 Feb;52(3):864-875

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N-acetyltransferase 10 Promotes Cervical Cancer Progression Via N4-acetylation of SLC7A5 mRNA.

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Frontiers in bioscience (Landmark edition) 2025 Feb 20;30(2):26756

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Sestrin 2 Regulates Milk Protein Synthesis through a LAT1/mTOR Pathway.

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FBW7/GSK3β mediated degradation of IGF2BP2 inhibits IGF2BP2-SLC7A5 positive feedback loop and radioresistance in lung cancer.

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Journal of experimental & clinical cancer research : CR 2024 Jan 29;43(1):34

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RNA-binding protein YBX3 promotes PPARγ-SLC3A2 mediated BCAA metabolism fueling brown adipogenesis and thermogenesis.

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Science advances 2023 Jan 6;9(1):eade9120

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ZNF24 regulates the progression of KRAS mutant lung adenocarcinoma by promoting SLC7A5 translation.

Jia D, Li L, Wang P, Feng Q, Pan X, Lin P, Song S, Yang L, Yang J
Frontiers in oncology 2022;12:1043177

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CircARID1A binds to IGF2BP3 in gastric cancer and promotes cancer proliferation by forming a circARID1A-IGF2BP3-SLC7A5 RNA-protein ternary complex.

Ma Q, Yang F, Huang B, Pan X, Li W, Yu T, Wang X, Ran L, Qian K, Li H, Li H, Liu Y, Liang C, Ren J, Zhang Y, Wang S, Xiao B
Journal of experimental & clinical cancer research : CR 2022 Aug 19;41(1):251