Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 11560-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11560-1-AP, RRID:AB_2127771
- Product name
- ING2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ING2 antibody (Cat. #11560-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ING2 Controls Mitochondrial Respiration via Modulating MRPL12 Ubiquitination in Renal Tubular Epithelial Cells.
Histone H3 N-terminal mimicry drives a novel network of methyl-effector interactions.
Antithetic hTERT Regulation by Androgens in Prostate Cancer Cells: hTERT Inhibition Is Mediated by the ING1 and ING2 Tumor Suppressors.
Expression pattern and level of ING5 protein in normal and cancer tissues.
A novel crosstalk between the tumor suppressors ING1 and ING2 regulates androgen receptor signaling.
Expression profiles of inhibitor of growth protein 2 in normal and cancer tissues: An immunohistochemical screening analysis.
Knockdown of inhibitor of growth protein 2 inhibits cell invasion and enhances chemosensitivity to 5-FU in human gastric cancer cells.
Identification of a novel function for the chromatin remodeling protein ING2 in muscle differentiation.
Human family with sequence similarity 60 member A (FAM60A) protein: a new subunit of the Sin3 deacetylase complex.
Deacetylase inhibitors dissociate the histone-targeting ING2 subunit from the Sin3 complex.
Decreased expression of ING2 gene and its clinicopathological significance in hepatocellular carcinoma.
Yang Y, Li C, Gu X, Zhen J, Zhu S, Lv T, Wan Q, Liu Y
Frontiers in cell and developmental biology 2021;9:700195
Frontiers in cell and developmental biology 2021;9:700195
Histone H3 N-terminal mimicry drives a novel network of methyl-effector interactions.
Chen J, Horton J, Sagum C, Zhou J, Cheng X, Bedford MT
The Biochemical journal 2021 May 28;478(10):1943-1958
The Biochemical journal 2021 May 28;478(10):1943-1958
Antithetic hTERT Regulation by Androgens in Prostate Cancer Cells: hTERT Inhibition Is Mediated by the ING1 and ING2 Tumor Suppressors.
Bartsch S, Mirzakhani K, Neubert L, Stenzel A, Ehsani M, Esmaeili M, Pungsrinont T, Kacal M, Rasa SMM, Kallenbach J, Damodaran D, Ribaudo F, Grimm MO, Neri F, Baniahmad A
Cancers 2021 Aug 10;13(16)
Cancers 2021 Aug 10;13(16)
Expression pattern and level of ING5 protein in normal and cancer tissues.
Yang XF, Shen DF, Zhao S, Ren TR, Gao Y, Shi S, Wu JC, Sun HZ, Zheng HC
Oncology letters 2019 Jan;17(1):63-68
Oncology letters 2019 Jan;17(1):63-68
A novel crosstalk between the tumor suppressors ING1 and ING2 regulates androgen receptor signaling.
Esmaeili M, Pungsrinont T, Schaefer A, Baniahmad A
Journal of molecular medicine (Berlin, Germany) 2016 Oct;94(10):1167-1179
Journal of molecular medicine (Berlin, Germany) 2016 Oct;94(10):1167-1179
Expression profiles of inhibitor of growth protein 2 in normal and cancer tissues: An immunohistochemical screening analysis.
Zhao S, Yang XF, Gou WF, Lu H, Li H, Zhu ZT, Sun HZ, Zheng HC
Molecular medicine reports 2016 Feb;13(2):1881-7
Molecular medicine reports 2016 Feb;13(2):1881-7
Knockdown of inhibitor of growth protein 2 inhibits cell invasion and enhances chemosensitivity to 5-FU in human gastric cancer cells.
Zhong J, Yang L, Liu N, Zheng J, Lin CY
Digestive diseases and sciences 2013 Nov;58(11):3189-97
Digestive diseases and sciences 2013 Nov;58(11):3189-97
Identification of a novel function for the chromatin remodeling protein ING2 in muscle differentiation.
Eapen SA, Netherton SJ, Sarker KP, Deng L, Chan A, Riabowol K, Bonni S
PloS one 2012;7(7):e40684
PloS one 2012;7(7):e40684
Human family with sequence similarity 60 member A (FAM60A) protein: a new subunit of the Sin3 deacetylase complex.
Smith KT, Sardiu ME, Martin-Brown SA, Seidel C, Mushegian A, Egidy R, Florens L, Washburn MP, Workman JL
Molecular & cellular proteomics : MCP 2012 Dec;11(12):1815-28
Molecular & cellular proteomics : MCP 2012 Dec;11(12):1815-28
Deacetylase inhibitors dissociate the histone-targeting ING2 subunit from the Sin3 complex.
Smith KT, Martin-Brown SA, Florens L, Washburn MP, Workman JL
Chemistry & biology 2010 Jan 29;17(1):65-74
Chemistry & biology 2010 Jan 29;17(1):65-74
Decreased expression of ING2 gene and its clinicopathological significance in hepatocellular carcinoma.
Zhang HK, Pan K, Wang H, Weng DS, Song HF, Zhou J, Huang W, Li JJ, Chen MS, Xia JC
Cancer letters 2008 Mar 18;261(2):183-92
Cancer letters 2008 Mar 18;261(2):183-92
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 11560-1-AP(ING2 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 11560-1-AP(ING2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ING2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ING2. This antibody recognizes human, mouse, rat antigen. The ING2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.