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- References [21]
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- Product number
- 11283-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11283-1-AP, RRID:AB_2203508
- Product name
- TMPRSS4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TMPRSS4 antibody (Cat. #11283-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Effects of transmembrane serine protease 4 on the survival in patients with pancreatic ductal adenocarcinoma undergoing surgery followed by adjuvant chemotherapy.
Utility of TMPRSS4 as a Prognostic Biomarker and Potential Therapeutic Target in Patients with Gastric Cancer.
TSPAN1, TMPRSS4, SDR16C5, and CTSE as Novel Panel for Pancreatic Cancer: A Bioinformatics Analysis and Experiments Validation.
TMPRSS4 Promotes Cell Proliferation and Inhibits Apoptosis in Pancreatic Ductal Adenocarcinoma by Activating ERK1/2 Signaling Pathway.
TMPRSS4 overexpression promotes the metastasis of colorectal cancer and predicts poor prognosis of stage III-IV colorectal cancer.
Cardiac and Renal SARS-CoV-2 Viral Entry Protein Regulation by Androgens and Diet: Implications for Polycystic Ovary Syndrome and COVID-19.
Transmembrane Protease TMPRSS4 Promotes the Formation and Development of Mismatch Repair Deficient Colon Cancer Liver Metastasis.
Angiotensin-converting Enzyme 2-containing Small Extracellular Vesicles and Exomeres Bind the Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein.
TMPRSS4 Expression as a Marker of Recurrence in Patients with Lung Cancer.
TMPRSS4 induces cancer stem cell-like properties in lung cancer cells and correlates with ALDH expression in NSCLC patients.
TWIST1-Induced miR-424 Reversibly Drives Mesenchymal Programming while Inhibiting Tumor Initiation.
Methylation-induced downregulation of TFPI-2 causes TMPRSS4 overexpression and contributes to oncogenesis in a subset of non-small-cell lung carcinoma.
TMPRSS4 upregulates uPA gene expression through JNK signaling activation to induce cancer cell invasion.
The expression of TMPRSS4 and Erk1 correlates with metastasis and poor prognosis in Chinese patients with gastric cancer.
Prognostic value of TMPRSS4 expression in patients with breast cancer.
TMPRSS4 as a poor prognostic factor for triple-negative breast cancer.
High TMPRSS4 expression is a predictor of poor prognosis in cervical squamous cell carcinoma.
Expression of TMPRSS4 in patients with salivary adenoid cystic carcinoma: correlation with clinicopathological features and prognosis.
Radiation enhances long-term metastasis potential of residual hepatocellular carcinoma in nude mice through TMPRSS4-induced epithelial-mesenchymal transition.
A novel tripeptide, tyroserleutide, inhibits irradiation-induced invasiveness and metastasis of hepatocellular carcinoma in nude mice.
TMPRSS4 induces invasion and epithelial-mesenchymal transition through upregulation of integrin alpha5 and its signaling pathways.
Tazuma S, Sudo T, Ishikawa A, Yamaguchi A, Shibata Y, Ishida Y, Kuraoka K, Uemura K, Takahashi S, Tashiro H
Surgery today 2024 Oct;54(10):1208-1219
Surgery today 2024 Oct;54(10):1208-1219
Utility of TMPRSS4 as a Prognostic Biomarker and Potential Therapeutic Target in Patients with Gastric Cancer.
Tazawa H, Suzuki T, Saito A, Ishikawa A, Komo T, Sada H, Shimada N, Hadano N, Onoe T, Sudo T, Shimizu Y, Kuraoka K, Tashiro H
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2022 Feb;26(2):305-313
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2022 Feb;26(2):305-313
TSPAN1, TMPRSS4, SDR16C5, and CTSE as Novel Panel for Pancreatic Cancer: A Bioinformatics Analysis and Experiments Validation.
Ye H, Li T, Wang H, Wu J, Yi C, Shi J, Wang P, Song C, Dai L, Jiang G, Huang Y, Yu Y, Li J
Frontiers in immunology 2021;12:649551
Frontiers in immunology 2021;12:649551
TMPRSS4 Promotes Cell Proliferation and Inhibits Apoptosis in Pancreatic Ductal Adenocarcinoma by Activating ERK1/2 Signaling Pathway.
Gu J, Huang W, Zhang J, Wang X, Tao T, Yang L, Zheng Y, Liu S, Yang J, Zhu L, Wang H, Fan Y
Frontiers in oncology 2021;11:628353
Frontiers in oncology 2021;11:628353
TMPRSS4 overexpression promotes the metastasis of colorectal cancer and predicts poor prognosis of stage III-IV colorectal cancer.
Zhao XF, Yang YS, Gao DZ, Park YK
The International journal of biological markers 2021 Sep;36(3):23-32
The International journal of biological markers 2021 Sep;36(3):23-32
Cardiac and Renal SARS-CoV-2 Viral Entry Protein Regulation by Androgens and Diet: Implications for Polycystic Ovary Syndrome and COVID-19.
Rezq S, Huffman AM, Basnet J, Yanes Cardozo LL, Romero DG
International journal of molecular sciences 2021 Sep 9;22(18)
International journal of molecular sciences 2021 Sep 9;22(18)
Transmembrane Protease TMPRSS4 Promotes the Formation and Development of Mismatch Repair Deficient Colon Cancer Liver Metastasis.
Yang YS, Wen D, Zhao XF
Bulletin of experimental biology and medicine 2021 May;171(2):242-246
Bulletin of experimental biology and medicine 2021 May;171(2):242-246
Angiotensin-converting Enzyme 2-containing Small Extracellular Vesicles and Exomeres Bind the Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein.
Zhang Q, Jeppesen DK, Higginbotham JN, Franklin JL, Crowe JE Jr, Coffey RJ
Gastroenterology 2021 Feb;160(3):958-961.e3
Gastroenterology 2021 Feb;160(3):958-961.e3
TMPRSS4 Expression as a Marker of Recurrence in Patients with Lung Cancer.
Chikaishi Y, Uramoto H, Koyanagi Y, Yamada S, Yano S, Tanaka F
Anticancer research 2016 Jan;36(1):121-7
Anticancer research 2016 Jan;36(1):121-7
TMPRSS4 induces cancer stem cell-like properties in lung cancer cells and correlates with ALDH expression in NSCLC patients.
de Aberasturi AL, Redrado M, Villalba M, Larzabal L, Pajares MJ, Garcia J, Evans SR, Garcia-Ros D, Bodegas ME, Lopez L, Montuenga L, Calvo A
Cancer letters 2016 Jan 28;370(2):165-76
Cancer letters 2016 Jan 28;370(2):165-76
TWIST1-Induced miR-424 Reversibly Drives Mesenchymal Programming while Inhibiting Tumor Initiation.
Drasin DJ, Guarnieri AL, Neelakantan D, Kim J, Cabrera JH, Wang CA, Zaberezhnyy V, Gasparini P, Cascione L, Huebner K, Tan AC, Ford HL
Cancer research 2015 May 1;75(9):1908-21
Cancer research 2015 May 1;75(9):1908-21
Methylation-induced downregulation of TFPI-2 causes TMPRSS4 overexpression and contributes to oncogenesis in a subset of non-small-cell lung carcinoma.
Hamamoto J, Soejima K, Naoki K, Yasuda H, Hayashi Y, Yoda S, Nakayama S, Satomi R, Terai H, Ikemura S, Sato T, Arai D, Ishioka K, Ohgino K, Betsuyaku T
Cancer science 2015 Jan;106(1):34-42
Cancer science 2015 Jan;106(1):34-42
TMPRSS4 upregulates uPA gene expression through JNK signaling activation to induce cancer cell invasion.
Min HJ, Lee Y, Zhao XF, Park YK, Lee MK, Lee JW, Kim S
Cellular signalling 2014 Feb;26(2):398-408
Cellular signalling 2014 Feb;26(2):398-408
The expression of TMPRSS4 and Erk1 correlates with metastasis and poor prognosis in Chinese patients with gastric cancer.
Luo ZY, Wang YY, Zhao ZS, Li B, Chen JF
PloS one 2013;8(7):e70311
PloS one 2013;8(7):e70311
Prognostic value of TMPRSS4 expression in patients with breast cancer.
Liang B, Wu M, Bu Y, Zhao A, Xie F
Medical oncology (Northwood, London, England) 2013 Jun;30(2):497
Medical oncology (Northwood, London, England) 2013 Jun;30(2):497
TMPRSS4 as a poor prognostic factor for triple-negative breast cancer.
Cheng D, Kong H, Li Y
International journal of molecular sciences 2013 Jul 12;14(7):14659-68
International journal of molecular sciences 2013 Jul 12;14(7):14659-68
High TMPRSS4 expression is a predictor of poor prognosis in cervical squamous cell carcinoma.
Cheng D, Liang B, Li Y
Cancer epidemiology 2013 Dec;37(6):993-7
Cancer epidemiology 2013 Dec;37(6):993-7
Expression of TMPRSS4 in patients with salivary adenoid cystic carcinoma: correlation with clinicopathological features and prognosis.
Dai W, Zhou Q, Xu Z, Zhang E
Medical oncology (Northwood, London, England) 2013 Dec;30(4):749
Medical oncology (Northwood, London, England) 2013 Dec;30(4):749
Radiation enhances long-term metastasis potential of residual hepatocellular carcinoma in nude mice through TMPRSS4-induced epithelial-mesenchymal transition.
Li T, Zeng ZC, Wang L, Qiu SJ, Zhou JW, Zhi XT, Yu HH, Tang ZY
Cancer gene therapy 2011 Sep;18(9):617-26
Cancer gene therapy 2011 Sep;18(9):617-26
A novel tripeptide, tyroserleutide, inhibits irradiation-induced invasiveness and metastasis of hepatocellular carcinoma in nude mice.
Jia JB, Wang WQ, Sun HC, Liu L, Zhu XD, Kong LQ, Chai ZT, Zhang W, Zhang JB, Xu HX, Zeng ZC, Wu WZ, Wang L, Tang ZY
Investigational new drugs 2011 Oct;29(5):861-72
Investigational new drugs 2011 Oct;29(5):861-72
TMPRSS4 induces invasion and epithelial-mesenchymal transition through upregulation of integrin alpha5 and its signaling pathways.
Kim S, Kang HY, Nam EH, Choi MS, Zhao XF, Hong CS, Lee JW, Lee JH, Park YK
Carcinogenesis 2010 Apr;31(4):597-606
Carcinogenesis 2010 Apr;31(4):597-606
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- BxPC-3 cells were subjected to SDS PAGE followed by western blot with 11283-1-AP(TMPRSS4 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 11283-1-AP(TMPRSS4 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TMPRSS4 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TMPRSS4. This antibody recognizes human,mouse,rat antigen. The TMPRSS4 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
