Explore
Validate
Learn
Western blotAntibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- PAB0244 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB0244, RRID:AB_1019046
- Product name
- CASP6 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against full length recombinant CASP6.
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Early processing of Bid and caspase-6, -8, -10, -14 in the canine brain during cardiac arrest and resuscitation.
Krajewska M, Rosenthal RE, Mikolajczyk J, Stennicke HR, Wiesenthal T, Mai J, Naito M, Salvesen GS, Reed JC, Fiskum G, Krajewski S
Experimental neurology 2004 Oct;189(2):261-79
Experimental neurology 2004 Oct;189(2):261-79
No comments: Submit comment
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of Caspase-6. Recombinant catalytically active CASP6 was western blotted with Active/Cleaved CASP6 polyclonal antibody (Cat # PAB0244) . The antisera detected both the large and small subunits of Active/Cleaved CASP6.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed paraffin-embedded tissue section of dog cerebellum stained for Active/Cleaved CASP6 expression. Using Active/Cleaved CASP6 polyclonal antibody (Cat # PAB0244) at 1 : 2000. Hematoxylin-eosin counterstain.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed paraffin-embedded tissue sections of human glioma stained for Active/Cleaved CASP6 expression. Using Active/Cleaved CASP6 polyclonal antibody (Cat # PAB0244) at 1 : 2000. Gemistocytoma (low grade tumor) at low (A) and high (B) magnification. Two examples of anaplastic, high grade (III) infiltrating gliomas (C and D) . Increased active/cleaved Caspase-6 may be seen in high grade, compared to low grade tumors. Hematoxylin-eosin counterstain.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
