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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB0423 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB0423, RRID:AB_982389
- Product name
- CASP6 (phospho S257) polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic phosphopeptide of CASP6.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Breaking the connection: caspase 6 disconnects intermediate filament-binding domain of periplakin from its actin-binding N-terminal region.
Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease.
Regulation of caspase-6 and FLIP by the AMPK family member ARK5.
Kalinin AE, Kalinin AE, Aho M, Uitto J, Aho S
The Journal of investigative dermatology 2005 Jan;124(1):46-55
The Journal of investigative dermatology 2005 Jan;124(1):46-55
Early N-terminal changes and caspase-6 cleavage of tau in Alzheimer's disease.
Horowitz PM, Patterson KR, Guillozet-Bongaarts AL, Reynolds MR, Carroll CA, Weintraub ST, Bennett DA, Cryns VL, Berry RW, Binder LI
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 Sep 8;24(36):7895-902
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004 Sep 8;24(36):7895-902
Regulation of caspase-6 and FLIP by the AMPK family member ARK5.
Suzuki A, Kusakai G, Kishimoto A, Shimojo Y, Miyamoto S, Ogura T, Ochiai A, Esumi H
Oncogene 2004 Sep 16;23(42):7067-75
Oncogene 2004 Sep 16;23(42):7067-75
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of CASP6 (phospho S257) polyclonal antibody (Cat # PAB0423) in mouse liver lysates (35 ug/lane). CASP6-pS257 (arrow) was detected using the purified Pab.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human cancer tissue reacted with CASP6 (phospho S257) polyclonal antibody (Cat # PAB0423) which was peroxidase-conjugated to the secondary antibody followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
