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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB2445 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2445, RRID:AB_1572140
- Product name
- CASP6 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of CASP6.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Streptococcus pneumoniae-induced caspase 6-dependent apoptosis in lung epithelium.
Caspases mediate processing of the capsid precursor and cell release of human astroviruses.
Apoptotic threshold is lowered by p53 transactivation of caspase-6.
Schmeck B, Gross R, N'Guessan PD, Hocke AC, Hammerschmidt S, Mitchell TJ, Rosseau S, Suttorp N, Hippenstiel S
Infection and immunity 2004 Sep;72(9):4940-7
Infection and immunity 2004 Sep;72(9):4940-7
Caspases mediate processing of the capsid precursor and cell release of human astroviruses.
Méndez E, Salas-Ocampo E, Arias CF
Journal of virology 2004 Aug;78(16):8601-8
Journal of virology 2004 Aug;78(16):8601-8
Apoptotic threshold is lowered by p53 transactivation of caspase-6.
MacLachlan TK, El-Deiry WS
Proceedings of the National Academy of Sciences of the United States of America 2002 Jul 9;99(14):9492-7
Proceedings of the National Academy of Sciences of the United States of America 2002 Jul 9;99(14):9492-7
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of CASP6 polyclonal antibody (Cat # PAB2445) in mouse liver tissue lysates (35 ug/lane). CASP6 (arrow) was detected using the purified polyclonal antibody.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma reacted with CASP6 polyclonal antibody (Cat # PAB2445) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
