ABIN264405

antibody from antibodies-online

Targeting: CASP6 MCH2

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN264405

Provider

antibodies-online

Product name

anti-Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) antibody

Antibody type

Monoclonal

Description

Purified

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

MCH2 14 1-190

Vial size

0.1 mg

Storage

Store the antibody at -20°C. Avoid repeated freezing and thawing.Shelf life: One year from despatch

References

Submitted references

Proteolytic activities that mediate apoptosis.

Kidd VJ
Annual review of physiology 1998;60:533-73

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Caspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosis.

Hirata H, Takahashi A, Kobayashi S, Yonehara S, Sawai H, Okazaki T, Yamamoto K, Sasada M
The Journal of experimental medicine 1998 Feb 16;187(4):587-600

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The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A.

Orth K, Chinnaiyan AM, Garg M, Froelich CJ, Dixit VM
The Journal of biological chemistry 1996 Jul 12;271(28):16443-6

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Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family.

Fernandes-Alnemri T, Litwack G, Alnemri ES
Cancer research 1995 Jul 1;55(13):2737-42

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB