ABIN356823

antibody from antibodies-online

Targeting: CASP6 MCH2

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN356823

Provider

antibodies-online

Product name

anti-Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6) (C-Term) antibody

Antibody type

Polyclonal

Antigen

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CASP6.

Description

Protein A Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Reactivity

Human, Mouse

Host

Rabbit

Epitope

C-Term

Vial size

0.4 mL

Concentration

0.25 mg/mL

Storage

Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Streptococcus pneumoniae-induced caspase 6-dependent apoptosis in lung epithelium.

Schmeck B, Gross R, N'Guessan PD, Hocke AC, Hammerschmidt S, Mitchell TJ, Rosseau S, Suttorp N, Hippenstiel S
Infection and immunity 2004 Sep;72(9):4940-7

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Caspases mediate processing of the capsid precursor and cell release of human astroviruses.

Méndez E, Salas-Ocampo E, Arias CF
Journal of virology 2004 Aug;78(16):8601-8

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Apoptotic threshold is lowered by p53 transactivation of caspase-6.

MacLachlan TK, El-Deiry WS
Proceedings of the National Academy of Sciences of the United States of America 2002 Jul 9;99(14):9492-7

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Intracellular redistribution of procaspases during TPA-induced differentiation of U937 human leukemic cells.

Sordet O, Rébé C, Dubrez-Daloz L, Boudard D, Solary E
Leukemia 2002 Aug;16(8):1569-70

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Caspase-6 role in apoptosis of human neurons, amyloidogenesis, and Alzheimer's disease.

LeBlanc A, Liu H, Goodyer C, Bergeron C, Hammond J
The Journal of biological chemistry 1999 Aug 13;274(33):23426-36