FNab01775

antibody from FineTest Biotech

Targeting: CLSPN

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Antibody data

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Validation data

Product number: FNab01775 - Provider product page
Provider: FineTest Biotech
Product name: CLSPN antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Required for checkpoint mediated cell cycle arrest in response to inhibition of DNA replication or to DNA damage induced by both ionizing and UV irradiation. Adapter protein which binds to BRCA1 and the checkpoint kinase CHEK1 and facilitates the ATR-dependent phosphorylation of both proteins. Can also bind specifically to branched DNA structures and may associate with S-phase chromatin following formation of the pre-replication complex(pre-RC). This may indicate a role for this protein as a sensor which monitors the integrity of DNA replication forks.
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: claspin homolog(Xenopus laevis)
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

CLSPN protein structure - FNab01775 shown in red.