Antibody data
- Antibody Data
- Antigen structure
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- Comments [0]
- Validations
- Blocking/Neutralizing [1]
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Validation data
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- Product number
- MAB7151 - Provider product page
- Provider
- R&D Systems
- Product name
- Human BMP-5 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human BMP-5 in direct ELISAs and Western blots. In direct ELISAs, 50% cross-reactivity with recombinant human (rh) BMP-6 is observed and no cross-reactivity with rhBMP-2, -3, -4, or -7 is observed.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
P22003
- Isotype
- IgG
- Antibody clone number
- 149107
- Vial size
- 500 ug
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
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Supportive validation
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- R&D Systems (provider)
- Main image
- Experimental details
- Alkaline Phosphatase Production Induced by BMP-5 and Neutralization by Human BMP-5 Antibody. Recombinant Human BMP-5 (Catalog # 615-BMC) induces alkaline phosphatase production in the ATDC5 mouse chondrogenic cell line in a dose-dependent manner (orange line). Alkaline phosphatase production elicited by Recombinant Human BMP-5 (1.5 µg/mL) is neutralized (green line) by increasing concen-trations of Mouse Anti-Human BMP-5 Monoclonal Antibody (Catalog # MAB7151). The ND50 is typically 2-10 µg/mL.